Structure and Classification of Viruses

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Questions and Answers

What is the main function of a virus particle?

  • To deliver its DNA or RNA into the host cell (correct)
  • To replicate its own genome
  • To generate energy for the host cell
  • To form a protective coat around the host cell

What is the role of the nucleoprotein in a virus?

  • To protect the host cell from viral infection
  • To form the protective coat of the virus
  • To deliver energy to the virus
  • To assist in the replication of the virus (correct)

What is the significance of viruses being unable to generate energy?

  • It allows them to become inert outside the host cell
  • It enables them to crystallize easily
  • It prevents them from replicating
  • It makes them dependent on host cell machinery for replication (correct)

What is the term used for a complete virus particle?

<p>Virion (C)</p> Signup and view all the answers

How are viruses classified based on their genome?

<p>By their RNA or DNA genome (C)</p> Signup and view all the answers

What does it mean for viruses to be viewed as mobile genetic elements?

<p>They can insert their DNA into host genome (A)</p> Signup and view all the answers

Which basic patterns does self-assembly of virus capsids follow?

<p>Helical and icosahedral symmetry (D)</p> Signup and view all the answers

What type of viruses exhibit a fringe of glycoprotein spikes or knobs, also called peplomers?

<p>Enveloped viruses (C)</p> Signup and view all the answers

Which morphology is characteristic of the nucleocapsids of many 'spherical' viruses?

<p>Icosahedral (B)</p> Signup and view all the answers

What does the genome of a virus consist of?

<p>DNA or RNA (C)</p> Signup and view all the answers

What is the genomic RNA strand called in orientation if it can serve as mRNA?

<p>Sense (positive sense, plus sense) (B)</p> Signup and view all the answers

What are the parameters for classification of viruses?

<p>Pathogenicity, ecological, physicochemical, genome composition (D)</p> Signup and view all the answers

Based on pathogenicity, how are viruses affecting the same tissue grouped together?

<p>Respiratory tract, gastrointestinal tract, nervous system, genitourinary system (C)</p> Signup and view all the answers

"Arboviruses" are viruses transmitted by:

<p>Blood sucking arthropods and vertebrate hosts (D)</p> Signup and view all the answers

"Roboviruses" are defined in the text as viruses with:

<p>&quot;Rodent reservoirs&quot; (B)</p> Signup and view all the answers

"Nucleocapsids" consist of a helical array of capsid proteins wrapped around a helical filament of:

<p>&quot;Nucleic acid&quot; (D)</p> Signup and view all the answers

"Monopartite genome" refers to a genome that occupies:

<p>&quot;One nucleic acid molecule&quot; (C)</p> Signup and view all the answers

"Families" and "genera" are terms used for classifying viruses based on:

<p>Morphology, genome structure, and replication (D)</p> Signup and view all the answers

Which virus family does not have an envelope?

<p>Adenoviridae (D)</p> Signup and view all the answers

Which virus family has a complex capsid symmetry?

<p>Herpesviridae (A)</p> Signup and view all the answers

Which virus family has a single-stranded DNA genome?

<p>Papoviridae (B)</p> Signup and view all the answers

Which RNA virus family has an icosahedral capsid symmetry?

<p>Togaviridae (B)</p> Signup and view all the answers

Which DNA virus family has an enveloped capsid?

<p>Papoviridae (B)</p> Signup and view all the answers

Which DNA virus family has a complex capsid symmetry?

<p>Herpesviridae (A)</p> Signup and view all the answers

Which RNA virus family has a single-stranded positive-sense genome?

<p>Astroviridae (C)</p> Signup and view all the answers

Which viruses are designated by a number for subspecies?

<p>Parvoviruses (A)</p> Signup and view all the answers

What is the nucleic acid type of Picornaviruses?

<p>SS(+) RNA (A)</p> Signup and view all the answers

What is the capsid symmetry of Caliciviruses?

<p>Icosahedral (C)</p> Signup and view all the answers

Which statement accurately describes the role of the viral genome in a complete virus particle?

<p>It is enclosed within the capsid and interacts with the host cell machinery for replication. (C)</p> Signup and view all the answers

What distinguishes viruses from other microorganisms in terms of energy generation?

<p>Viruses rely solely on the host cell's biochemical machinery for energy generation. (B)</p> Signup and view all the answers

What is the primary function of the nucleocapsid in a virus?

<p>Delivers the viral genome into the host cell. (C)</p> Signup and view all the answers

Why are viruses considered as mobile genetic elements?

<p>Viruses can integrate their genetic material into a host cell's genome. (A)</p> Signup and view all the answers

What characteristic distinguishes virions from host cell organelles?

<p>The presence of a RNA or DNA genome (B)</p> Signup and view all the answers

Which virus family is characterized by a simplex dsDNA and an icosahedral capsid symmetry?

<p>Papoviridae (C)</p> Signup and view all the answers

What is the family name for a virus with a single-stranded negative-sense RNA and a helical capsid symmetry?

<p>Rhabdoviridae (C)</p> Signup and view all the answers

Which virus family has a genome consisting of single-stranded positive-sense RNA and is enveloped with an icosahedral capsid symmetry?

<p>Coronaviridae (A)</p> Signup and view all the answers

Which virus family is characterized by a single-stranded positive-sense RNA and a capsid symmetry of unknown type?

<p>Flaviviridae (C)</p> Signup and view all the answers

What is the family name for a virus with a double-stranded DNA genome and an icosahedral capsid symmetry?

<p>Herpesviridae (A)</p> Signup and view all the answers

What is the term used for the nucleocapsids of many filamentous and pleomorphic viruses?

<p>Nucleicapsids (A)</p> Signup and view all the answers

Which criteria are NOT used for the classification and nomenclature of viruses as mentioned in the text?

<p>Pathogenicity (D)</p> Signup and view all the answers

Which type of genome necessitates different replication strategies for a virus?

<p>Multipartite genome (B)</p> Signup and view all the answers

What is the term for the genomic RNA strand of single-stranded RNA viruses in orientation if it can serve as mRNA?

<p>Positive sense (B)</p> Signup and view all the answers

Which feature is NOT used for the classification of viruses?

<p>Genetic origin (A)</p> Signup and view all the answers

Flashcards

Virus function

To infect a host cell and replicate itself

Nucleoprotein role

Protects genetic material and aids replication

Virus classification

Based on genome type (RNA, DNA)

Virus classification parameters

Morphology, replication strategy, and genome type

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Icosahedral symmetry

Common in RNA viruses (shape)

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Helical symmetry

Common in filamentous/pleomorphic viruses (shape)

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Nucleocapsid morphology

Characteristic 'spherical' shape

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Viral genome

DNA or RNA genetic material

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Positive-sense RNA

Can be directly used as mRNA

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Viral energy dependency

Rely on host cell's energy

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Virion

Complete virus particle

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Arbovirus

Virus transmitted by arthropods

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Monopartite genome

Single segment of genetic material

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Virus families/genera

Classification based on evolutionary relationships

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Herpesvirus envelope

No envelope

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Adenovirus symmetry

Complex capsid symmetry

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Parvovirus genome

Single-stranded DNA

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Picornavirus symmetry

Icosahedral capsid symmetry

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Picornavirus genome

Single-stranded positive-sense RNA

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Herpesvirus genome

Double-stranded DNA

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Mobile genetic elements

Can move genetic material between hosts

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Nucleocapsid function

Protect genetic material and facilitate replication

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Virus vs. other microorganisms

Viruses are unable to generate their own energy

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Study Notes

Virus Structure and Function

  • The main function of a virus particle is to infect a host cell and replicate itself.
  • The nucleoprotein plays a crucial role in a virus, as it protects the genetic material and helps in the replication process.

Virus Classification

  • Viruses are classified based on their genome, which can be single-stranded RNA, double-stranded DNA, or single-stranded DNA.
  • The parameters for classification of viruses include morphology, replication strategy, and genome type.

Virus Morphology

  • Icosahedral capsid symmetry is characteristic of many RNA viruses.
  • Helical symmetry is characteristic of many filamentous and pleomorphic viruses.
  • The nucleocapsids of many 'spherical' viruses have a characteristic "spherical" morphology.

Genome and Replication

  • The genome of a virus consists of genetic material, which can be DNA or RNA.
  • The genomic RNA strand of single-stranded RNA viruses is called "positive-sense" if it can serve as mRNA.
  • Viruses are unable to generate energy and rely on the host cell's energy sources.

Terms and Definitions

  • A complete virus particle is called a "virion".
  • "Arboviruses" are viruses transmitted by arthropods.
  • "Roboviruses" are viruses with a robot-like capsid structure.
  • "Nucleocapsids" consist of a helical array of capsid proteins wrapped around a helical filament of genetic material.
  • "Monopartite genome" refers to a genome that occupies a single segment of genetic material.
  • "Families" and "genera" are terms used for classifying viruses based on their evolutionary relationships.

Virus Families

  • The herpesvirus family does not have an envelope.
  • The adenovirus family has a complex capsid symmetry.
  • The parvovirus family has a single-stranded DNA genome.
  • The picornavirus family has an icosahedral capsid symmetry and a single-stranded positive-sense RNA genome.
  • The herpesvirus family has an enveloped capsid and a double-stranded DNA genome.

Other

  • Viruses are considered "mobile genetic elements" because they can move genetic material between hosts.
  • The primary function of the nucleocapsid is to protect the genetic material and facilitate replication.
  • Viruses are distinguished from other microorganisms by their inability to generate energy.

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