Stroke Awareness Quiz
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Questions and Answers

What are the two types of stroke mentioned in the text?

  • Ischemic and hemorrhagic (correct)
  • Hemorrhagic and embolic
  • Ischemic and transient ischemic attack
  • Thrombotic and embolic
  • Which risk factor for stroke is considered nonmodifiable?

  • Hypertension
  • Age (correct)
  • Physical inactivity
  • Smoking
  • What contributes to the pathophysiology of ischemic stroke?

  • Reversible ischemic changes in the brain
  • Irreversible cell death
  • Ischemia-induced edema formation and inflammatory cascades (correct)
  • Dysfunction of the blood-brain barrier
  • What is the brief episode of neurological dysfunction without acute infarction referred to as?

    <p>Transient ischemic attack (TIA)</p> Signup and view all the answers

    Which condition increases the risk of stroke due to the ineffective function of the left atrium?

    <p>Atrial fibrillation</p> Signup and view all the answers

    What is the primary prevention of stroke focused on?

    <p>Controlling blood pressure, smoking cessation, anticoagulation, aspirin and statin therapy, and other lifestyle modifications</p> Signup and view all the answers

    What are the two subtypes of ischemic stroke?

    <p>Thrombotic and embolic</p> Signup and view all the answers

    What refers to reversible ischemic changes in the brain?

    <p>Ischemic penumbra</p> Signup and view all the answers

    What contributes to the pathophysiology of hemorrhagic stroke?

    <p>Dysfunction of the blood-brain barrier (BBB)</p> Signup and view all the answers

    What can hemorrhagic stroke be intracerebral or?

    <p>Subarachnoid</p> Signup and view all the answers

    What are the complications of subarachnoid hemorrhage (SAH)?

    <p>Rebleeding, cerebral vasospasm, seizures, and non-neurologic complications such as cardiac ischemia and hyponatremia</p> Signup and view all the answers

    What are the modifiable risk factors for stroke?

    <p>Hypertension, hyperlipidemia, diabetes, smoking, alcohol consumption, and physical inactivity</p> Signup and view all the answers

    What is the term for the reversible ischemic changes in the brain?

    <p>Ischemic penumbra</p> Signup and view all the answers

    What is the primary cause of mortality after tissue plasminogen activator (tPA) treatment for hemorrhagic stroke?

    <p>Rebleeding</p> Signup and view all the answers

    What is the leading cause of disability?

    <p>Stroke</p> Signup and view all the answers

    What contributes to the pathophysiology of ischemic stroke?

    <p>Inflammatory cascades</p> Signup and view all the answers

    What is the term for the ineffective function of the left atrium, leading to clot formation and embolization?

    <p>Atrial fibrillation</p> Signup and view all the answers

    What are the two subtypes of ischemic stroke?

    <p>Thrombotic and embolic</p> Signup and view all the answers

    What are the complications of subarachnoid hemorrhage (SAH)?

    <p>Cerebral vasospasm and seizures</p> Signup and view all the answers

    What is the brief episode of neurological dysfunction without acute infarction referred to as?

    <p>Transient ischemic attack (TIA)</p> Signup and view all the answers

    What are the nonmodifiable risk factors for stroke?

    <p>Age, gender, and race</p> Signup and view all the answers

    What is the term for the irreversible cell death in ischemic stroke?

    <p>Ischemic infarction</p> Signup and view all the answers

    What are the modifiable risk factors for stroke?

    <p>Smoking, alcohol consumption, and physical inactivity</p> Signup and view all the answers

    What is the term for the reversible ischemic changes in the brain?

    <p>Ischemic penumbra</p> Signup and view all the answers

    What are the three structures found in the Brain Micro-Vessel Endothelium?

    <p>Tight intercellular junctions, limited pinocytic intracellular vesicles, abundant mitochondria</p> Signup and view all the answers

    What are the four functions of the BBB?

    <p>Paracellular barrier, transcellular barrier, enzymatic barrier, cerebral endothelium</p> Signup and view all the answers

    What is the primary function of the paracellular barrier of the BBB?

    <p>Restricts the free movement of water-soluble compounds</p> Signup and view all the answers

    Which structure surrounds the brain micro-vessel endothelium?

    <p>Basement membrane</p> Signup and view all the answers

    What is the composition of the basement membrane surrounding the brain micro-vessel endothelium?

    <p>40-50nm thick</p> Signup and view all the answers

    What is the role of pericytes in the BBB?

    <p>Contain smooth muscle</p> Signup and view all the answers

    Which enzymes are part of the enzymatic barrier of the BBB?

    <p>Acetylcholinesterase, alkaline phosphatase, gamma-glutamyl transpeptidase, monoamine oxidases</p> Signup and view all the answers

    What is the function of the transcellular barrier of the BBB?

    <p>Inhibits transport of substances to the cytoplasm</p> Signup and view all the answers

    What is the role of astrocyte envelope in the BBB?

    <p>Abluminal vessel surface</p> Signup and view all the answers

    What is the primary function of the cerebral endothelium of the BBB?

    <p>Expresses a large number of efflux transporters</p> Signup and view all the answers

    What is the role of mitochondria in the Brain Micro-Vessel Endothelium?

    <p>Abundant mitochondria</p> Signup and view all the answers

    What is the term for the fully differentiated neurovascular system in the brain?

    <p>Highly specialized brain endothelial structure</p> Signup and view all the answers

    Study Notes

    Stroke and its Types, Risk Factors, and Complications

    • Stroke is the leading cause of disability.
    • Two types of stroke are ischemic and hemorrhagic.
    • Nonmodifiable risk factors for stroke include age, gender, race, ethnicity, and history of stroke.
    • Modifiable risk factors for stroke include medical conditions and behaviors such as hypertension, hyperlipidemia, diabetes, smoking, alcohol consumption, and physical inactivity.
    • Ischemic stroke occurs when oxygenated blood to the brain is blocked, with thrombotic and embolic being the two subtypes.
    • Ischemia-induced edema formation and inflammatory cascades contribute to the pathophysiology of ischemic stroke.
    • Hemorrhagic stroke occurs due to the dysfunction of the blood-brain barrier (BBB), leading to mortality after tissue plasminogen activator (tPA) treatment.
    • Transient ischemic attack (TIA) is a brief episode of neurological dysfunction without acute infarction, with clinical manifestations linked to specific cerebral arteries.
    • Ischemic penumbra refers to reversible ischemic changes in the brain, while the ischemic core involves irreversible cell death.
    • Atrial fibrillation increases the risk of stroke due to the ineffective function of the left atrium, leading to clot formation and embolization.
    • Primary prevention of stroke involves controlling blood pressure, smoking cessation, anticoagulation, aspirin and statin therapy, and other lifestyle modifications.
    • Hemorrhagic stroke can be intracerebral or subarachnoid, with risk factors including hypertension, smoking, alcohol abuse, and certain medical conditions.
    • Complications of subarachnoid hemorrhage (SAH) include rebleeding, cerebral vasospasm, seizures, and non-neurologic complications such as cardiac ischemia and hyponatremia.

    Stroke and its Types, Risk Factors, and Complications

    • Stroke is the leading cause of disability.
    • Two types of stroke are ischemic and hemorrhagic.
    • Nonmodifiable risk factors for stroke include age, gender, race, ethnicity, and history of stroke.
    • Modifiable risk factors for stroke include medical conditions and behaviors such as hypertension, hyperlipidemia, diabetes, smoking, alcohol consumption, and physical inactivity.
    • Ischemic stroke occurs when oxygenated blood to the brain is blocked, with thrombotic and embolic being the two subtypes.
    • Ischemia-induced edema formation and inflammatory cascades contribute to the pathophysiology of ischemic stroke.
    • Hemorrhagic stroke occurs due to the dysfunction of the blood-brain barrier (BBB), leading to mortality after tissue plasminogen activator (tPA) treatment.
    • Transient ischemic attack (TIA) is a brief episode of neurological dysfunction without acute infarction, with clinical manifestations linked to specific cerebral arteries.
    • Ischemic penumbra refers to reversible ischemic changes in the brain, while the ischemic core involves irreversible cell death.
    • Atrial fibrillation increases the risk of stroke due to the ineffective function of the left atrium, leading to clot formation and embolization.
    • Primary prevention of stroke involves controlling blood pressure, smoking cessation, anticoagulation, aspirin and statin therapy, and other lifestyle modifications.
    • Hemorrhagic stroke can be intracerebral or subarachnoid, with risk factors including hypertension, smoking, alcohol abuse, and certain medical conditions.
    • Complications of subarachnoid hemorrhage (SAH) include rebleeding, cerebral vasospasm, seizures, and non-neurologic complications such as cardiac ischemia and hyponatremia.

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    Description

    Test your knowledge about stroke and its types, risk factors, and complications with this informative quiz. Explore the differences between ischemic and hemorrhagic strokes, learn about modifiable and nonmodifiable risk factors, and understand the potential complications associated with this leading cause of disability.

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