Podcast
Questions and Answers
Which of the following physiological responses to stress are directly targeted by beta blockers?
Which of the following physiological responses to stress are directly targeted by beta blockers?
- Heightened alertness and cognitive function
- Increased negative thinking and irritability
- Decreased appetite and insomnia
- Elevated heart rate and blood pressure (correct)
Beta blockers directly address the psychological symptoms of stress, such as restlessness and negative thinking.
Beta blockers directly address the psychological symptoms of stress, such as restlessness and negative thinking.
False (B)
What is the main action of beta blockers on the nervous system in response to stress?
What is the main action of beta blockers on the nervous system in response to stress?
antagonistic action
Selective beta blockers target cardiac output by blocking ______ receptors.
Selective beta blockers target cardiac output by blocking ______ receptors.
Match the type of beta blocker with its receptor target:
Match the type of beta blocker with its receptor target:
According to Lockwood's (1989) study on musicians, what percentage of symphony orchestra musicians used beta blockers to manage performance anxiety?
According to Lockwood's (1989) study on musicians, what percentage of symphony orchestra musicians used beta blockers to manage performance anxiety?
The World Anti-Doping Agency permits the use of beta blockers in sports to improve performance under pressure.
The World Anti-Doping Agency permits the use of beta blockers in sports to improve performance under pressure.
In the study by Neftel et al. (1982) on musicians, which specific beta blocker was used to reduce physiological signs of stress?
In the study by Neftel et al. (1982) on musicians, which specific beta blocker was used to reduce physiological signs of stress?
Beta blockers may reduce the physiological response to stress, but research by Schweizer et al. (1991) indicates that they may not significantly affect an individual’s ______ ratings of stress.
Beta blockers may reduce the physiological response to stress, but research by Schweizer et al. (1991) indicates that they may not significantly affect an individual’s ______ ratings of stress.
According to Schwabe et al. (1990), how did beta blockers affect the goal orientation of stressed individuals compared to those given a placebo?
According to Schwabe et al. (1990), how did beta blockers affect the goal orientation of stressed individuals compared to those given a placebo?
The primary benefit of beta blockers is that they address the root causes of stress, such as personality traits or significant life events.
The primary benefit of beta blockers is that they address the root causes of stress, such as personality traits or significant life events.
What common side effect is associated with beta blockers due to their action of slowing down the heart rate?
What common side effect is associated with beta blockers due to their action of slowing down the heart rate?
What ethical concern is raised by the use of beta blockers in competitive sports?
What ethical concern is raised by the use of beta blockers in competitive sports?
When beta blockers are prescribed for stress, it is considered '______' use, because they were originally developed to treat cardiovascular problems.
When beta blockers are prescribed for stress, it is considered '______' use, because they were originally developed to treat cardiovascular problems.
Statistics indicate that prescriptions for beta blockers decreased significantly between 2012 and 2013.
Statistics indicate that prescriptions for beta blockers decreased significantly between 2012 and 2013.
Flashcards
Beta Blockers
Beta Blockers
Drugs that reduce physical stress symptoms (increased heart rate, blood pressure) by blocking adrenaline and noradrenaline receptor sites, leading to calmness.
Selective Beta Blockers
Selective Beta Blockers
Beta blockers that target cardiac output by blocking beta 1 receptors, slowing heart rate.
Non-Selective Beta Blockers
Non-Selective Beta Blockers
Beta blockers that target adrenaline and noradrenaline in the heart, liver, and kidneys by blocking both beta1 and beta2 receptors.
Beta Blockers & Performance Anxiety
Beta Blockers & Performance Anxiety
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Subjective Experience of Anxiety
Subjective Experience of Anxiety
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Beta Blockers & Goal Orientation
Beta Blockers & Goal Orientation
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The 'Plaster Effect'
The 'Plaster Effect'
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Beta Blockers - Common Side Effects
Beta Blockers - Common Side Effects
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Ethical Issue: Performance Enhancement
Ethical Issue: Performance Enhancement
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Prescribed 'Off Label'
Prescribed 'Off Label'
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Over-prescription Risks
Over-prescription Risks
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Overall Beta Blocker Impact
Overall Beta Blocker Impact
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Study Notes
Biological Explanations of Stress
- Biological approaches to modifying stress target the physiological response, particularly the sympathetic nervous system.
- Beta blockers are drugs prescribed to reduce the physical symptoms of stress, like increased heart rate and blood pressure.
- They have an antagonistic action, reducing nervous system activity by blocking receptor sites for adrenaline and noradrenaline.
- Beta blockers lower heart rate, blood pressure, and breathing rate, inducing a calmer state.
- They are commonly prescribed for both acute and chronic stress, and treat stress-related conditions like angina and hypertension.
- While they don't directly affect psychological symptoms, they can reduce palpitations and sweating, helping individuals feel calmer.
Types of Beta Blockers
- Selective beta blockers (e.g., atenolol) target cardiac output by blocking beta 1 receptors: slowing heart rate.
- Non-selective beta blockers (e.g., propranolol) target adrenaline and noradrenaline in the heart, liver, and kidneys by blocking beta1 and beta2 receptors.
- Lack of clinical trials for stress-related use due to original development for heart conditions leads to unsubstantiated safety and effectiveness claims.
Examples of Beta Blocker Use
- Lockwood's (1989) study showed that 27% of musicians used beta blockers to reduce performance anxiety, suggesting a calming effect and improved performance.
- The World Anti-Doping Agency has banned beta blockers due to their performance-enhancing effects.
Effectiveness
- Beta blockers improve performance by reducing performance anxieties.
- Neftel et al. (1982) found that musicians taking atenolol experienced fewer physiological signs of stress, lower heart rates and blood pressure, and played more accurately.
- Beta blockers reduce the physiological response to stress, but its effectiveness in reducing an individual’s perception of stress is questionable.
- Schweizer et al. (1991) found that beta blockers inhibited the physiological response to stress during exams but did not significantly affect students' subjective ratings of stress.
- Stressed individuals often develop coping habits like alcoholism, smoking, or changes in eating/sleeping habits.
- Schwabe et al. (1990) found that stressed individuals given beta blockers remained goal-oriented, unlike those given placebos, suggesting beta blockers help focus on problems rather than distractions.
- Beta blockers provide a 'plaster effect' by reducing physiological symptoms without addressing underlying psychological causes like personality traits, life events, or lack of support.
- Critics argue that approaches like stress inoculation training, which address the root cause, are more effective in the long term.
Ethical Implications
- Side effects such as fatigue, dizziness, poor circulation, gastrointestinal symptoms, sexual dysfunction, and weight gain must be considered.
- Less common side effects include difficulty breathing, high blood sugar, depression, insomnia, and nightmares.
- There are risks associated with addiction and over-reliance, with people feeling unable to cope without beta blockers.
- Sudden cessation of beta blockers can cause palpitations and increased blood pressure.
- Beta blockers can enhance performance in music and sports.
- The World Anti-Doping Agency prohibits beta blocker use in many sports due to the unfair advantage they provide.
- Beta blocker use removes responsibility for managing one’s own stress and promotes a deterministic view, assuming behavior is controlled by physiology.
Social Implications
- Beta blockers are prescribed 'off label' for stress, without the same rigorous testing.
- Increased demand for beta blockers provides a quick solution for GPs but creates dependency.
- Repeat prescriptions are common since beta blockers do not address the root cause.
- "Off-label" drugs can cause harm.
- Prescriptions for beta blockers increased by 7% between 2012 and 2013.
- The Scottish Medical Council (2017) raised concerns about propranolol prescriptions for under-18s after deaths due to toxicity.
- "Talking therapies" are preferable for building resilience and long-term coping strategies.
Conclusion
- Beta blockers effectively reduce performance anxiety and destructive coping habits.
- They do not reduce the subjective experience of anxiety or address the root causes of stress.
- Safety testing is "off-label".
- There are problems with side effects, dependency, and disempowerment.
- Should be used as an addition to talking therapies for a long-term solution.
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