Storage of Crude Drugs Quiz
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Questions and Answers

How should opium be stored to prevent loss of morphine?

Opium should be stored in well-closed containers and not kept in the open.

What precautions should be taken when storing digitalis?

Digitalis should be stored with a dehydrating agent like silica gel or calcium chloride.

Why should squill be stored in a tightly closed container?

Squill should be stored in a tightly closed container to prevent the mucilage from absorbing moisture.

What is the recommended storage condition for biological preparations?

<p>Biological preparations should be stored at low temperatures.</p> Signup and view all the answers

List three characteristics of ideal storage facilities for medicinal materials.

<p>Ideal storage facilities should be well aerated, dry, and protected from light.</p> Signup and view all the answers

Why is it important to store medicinal material on shelves that keep a sufficient distance from the walls?

<p>Storing material on shelves away from walls prevents pest infestation.</p> Signup and view all the answers

What are the ideal conditions for storing drugs?

<p>Cool, dry place away from light</p> Signup and view all the answers

How should volatile oils and fixed oils be stored?

<p>In sealed, well-filled containers in a cool, dark place</p> Signup and view all the answers

Why is air-drying drugs not recommended?

<p>They are liable to attack by insects and other pests</p> Signup and view all the answers

What can deteriorate crude drugs?

<p>Moisture and light</p> Signup and view all the answers

What is recommended for some plants before storage to reduce microbial contamination?

<p>Sterilization</p> Signup and view all the answers

How should drugs like Digitalis and Indian hemp be stored to maintain their activity?

<p>In sealed containers with a dehydrating agent</p> Signup and view all the answers

What are the ideal storage temperatures for fresh medicinal plant materials and frozen products?

<p>Fresh medicinal plant materials should be stored at 2-8°C, while frozen products should be stored at less than -20°C.</p> Signup and view all the answers

What type of containers should be used to store fragile medicinal plant materials?

<p>Fragile medicinal plant materials should be packaged in rigid containers.</p> Signup and view all the answers

Why should wooden boxes, sacks, bales, and paper bags not be used for storage of crude drugs?

<p>Wooden boxes, sacks, bales, and paper bags should not be used for storage of crude drugs because they reabsorb moisture.</p> Signup and view all the answers

How should dried medicinal plants/herbal drugs, including essential oils, be stored?

<p>They should be stored in a dry, well-aerated building with limited daily temperature fluctuations.</p> Signup and view all the answers

What are the quality requirements for materials used in packaging medicinal plant materials?

<p>Materials used for packaging should be nonpolluting, clean, dry, undamaged, and should conform to the quality requirements for the medicinal plant materials.</p> Signup and view all the answers

What should be implemented to eliminate substandard materials, contaminants, and foreign matter during the final stages of packaging?

<p>Continuous in-process quality control measures should be implemented.</p> Signup and view all the answers

Study Notes

Storage of Crude Drugs

  • The most common method for preserving plant material is drying.
  • All drugs should be preserved in well-closed and filled containers, stored in water-proof, fire-proof, and rodent-proof premises.

Examples of Poor Storage Conditions

  • Opium: Loss of morphine occurs when stored in the open.
  • Digitalis: Should be stored with a dehydrating agent to prevent enzymic reactions.
  • Squill: Should be stored in a tightly closed container to prevent moisture absorption.
  • Biological preparations: Need to be stored at low temperatures to preserve their activities.

Storage Premises

  • Storage facilities should be well-aerated, dry, and protected from light, with air-conditioning and humidity control equipment.
  • The floor should be tidy, without cracks, and easy to clean.
  • Shelves should keep the material a sufficient distance from the walls, with measures to prevent pest infestation.

Storage Conditions

  • Plastic sacks effectively seal the contents, but long-term storage is not recommended.
  • Ideal conditions are always in a cool and dry place, away from light.
  • Temperature, water, and light are the main factors that affect drugs.

Special Storage Requirements

  • Digitalis and Indian hemp should not be allowed to become air-dry, or they lose a considerable part of their activity.
  • Volatile oils and fixed oils should be stored in sealed, well-filled containers in a cool, dark place.
  • Air-dry drugs are liable to attack by insects and other pests, and should be examined frequently during storage.

Deterioration of Crude Drugs

  • Moisture can cause rapid changes of active principles due to enzymes requiring a sufficient moisture to activate them.
  • Light can affect drugs, especially those containing marked colors.
  • Hygroscopic materials can become deteriorated by absorbing moisture in a humid atmosphere.

Packaging and Storage

  • Processed medicinal plant materials should be packaged in clean, dry boxes, sacks, bags, or other containers in accordance with standard operating procedures.
  • Materials used for packaging should be non-polluting, clean, dry, and in undamaged condition.
  • Fresh medicinal plant materials should be stored at appropriate low temperatures, ideally at 2-8°C; frozen products should be stored at less than -20°C.
  • Small quantities of crude drugs can be stored in air-tight, moisture-proof, and light-proof containers.
  • Wooden boxes, sacks, bales, and paper bags should not be used for storage of crude drugs.

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Description

Test your knowledge on the storage requirements for preserving plant material and crude drugs. Learn about the importance of well-closed containers, water-proof premises, and preventing loss of phytochemical constituents through enzymatic reactions. Identify poor storage conditions for drugs like Opium.

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