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Stimulants Overview

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Questions and Answers

What is the primary action of stimulants on the brain?

Primarily act on D2 receptors in the prefrontal cortex

Increase norepinephrine (NE) and dopamine (DA) equally

Increase only serotonin levels in the brain

Primarily act on D1 receptors in the prefrontal cortex (correct)

Which of the following is a potential side effect of stimulants?

Improved sleep quality

Increased anxiety and agitation (correct)

Reduced blood pressure and pulse

Enhanced growth in children

What is a common reason for using stimulants off-label?

To reverse sexual dysfunction (correct)

To treat narcolepsy

To manage chronic pain

To improve memory retention

Why is it important to monitor heart-related factors while on stimulant medication?

Due to the risk of sudden cardiac death in patients with pre-existing cardiac structural abnormalities Signup and view all the answers

What is a typical side effect that may occur due to stimulant use, especially in high doses?

Development of tics Signup and view all the answers

How does the FDA approve methylphenidate for use?

For ADHD in adults and children aged 6 and above Signup and view all the answers

What is the main mechanism of action of methylphenidate?

Blocks reuptake transporters for DA and NE Signup and view all the answers

Which isomer of methylphenidate is more potent?

The d-isomer Signup and view all the answers

What are common side effects associated with methylphenidate use?

Tachycardia and insomnia Signup and view all the answers

What is a rare and dangerous side effect associated with methylphenidate overdose?

Psychosis Signup and view all the answers

Which of the following medications may interact with methylphenidate by inhibiting its metabolism?

SSRI antidepressants Signup and view all the answers

For which condition is methylphenidate FDA approved?

ADHD Signup and view all the answers