30 Questions
What is one of the uses of microbes in pharmacy?
Manufacturing antibiotics
Which test is commonly used to determine antibiotic, vitamin, and amino acid concentrations?
Ames mutagenicity test
What is a potential harmful effect of microbes in pharmacy related to sterile medicines?
Product deterioration
Which topic is associated with controlling antibiotic resistance in the context of microorganisms?
Immunology and infectious diseases
What is one of the roles of microbial genetics in pharmacy?
Providing a reservoir of antibiotic resistance genes
In pharmacy, what is an important aspect associated with microbial biofilms?
Controlling antibiotic resistance
What type of bacteria are primarily responsible for the production of dextrans?
Leuconostoc
What is the molecular weight range of dextrans?
15,000 - 20,000,000
How are dextrans commonly used in medical applications?
As plasma expanders
Which area in pharmaceutical microbiology focuses on preventing microbial contamination in drugs and sterile products?
Quality control
What is the main goal of sterilization in pharmaceutical preparations?
To eliminate all forms of life and biological agents
How do dextrans contribute to ulcerated wounds or burns?
By absorbing fluid exudates and forming a hydrophilic layer
What is the purpose of passing materials like scalpels through a flame multiple times?
To kill vegetative cells effectively
Why is incineration considered suitable only for certain materials?
It results in loss of material
What distinguishes hot air oven sterilization from flame sterilization?
Heat transfer by radiation, conduction, and convection
Which method is known for being limited to materials that can withstand exposure to flame?
Passing materials through a flame
What precaution must be taken when using a hot air oven for sterilization?
Having adequate insulation in the oven
Why is incineration recommended for materials like soiled dressings and animal carcasses?
Due to their nature and need for complete disposal
What is a disadvantage of using gamma rays for sterilization?
Leads to browning of glasswares
Why is Bacillus pumilus E601 used in the evaluation of sterilization processes?
To evaluate the sterilization process
What is the major purpose of filtration in sterilization?
To remove microorganisms
How does gamma irradiation impact the flavor of certain foods?
Impairs the flavor
What is the function of membrane filters with pore sizes between 0.2 - 0.45μm?
Remove particles from solutions
Why is sterilization by filtration considered different from other methods?
It separates out microorganisms without killing them
What is the purpose of using a HEPA filter in a biological safety cabinet?
To remove microbes from the air
What is the efficiency of HEPA filters when removing particles larger than 0.3 μm in diameter?
At least 99.97%
Which type of liquids are suitable for filtration using HEPA filters?
Sugar solutions
How is the efficiency of a HEPA filter monitored?
With the dioctylphthalate (DOP) particle test
In what type of areas are HEPA filters commonly used aside from biological safety cabinets?
Orthopedic implant procedure rooms
What role do aluminum separators play in HEPA filters?
Enhance the stability of the filter
Test your knowledge on different sterilization methods and procedures commonly used in laboratories and healthcare settings. Questions cover topics like incineration, flaming, and their limitations.
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