Sterilants

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Questions and Answers

Which of the following best describes a sterilant?

  • A chemical agent with low toxicity for host cells used on animate surfaces
  • A chemical agent that kills microorganisms on inanimate surfaces
  • A method of disinfection that kills both vegetative cells and spores (correct)
  • A physical procedure that inhibits or kills microorganisms on inanimate surfaces

What is the main difference between a disinfectant and an antiseptic?

  • Disinfectants are chemical agents, while antiseptics are physical procedures
  • Disinfectants are used on inanimate surfaces, while antiseptics are used on animate surfaces (correct)
  • Disinfectants kill both vegetative cells and spores, while antiseptics only kill vegetative cells
  • Disinfectants have low toxicity for host cells, while antiseptics have high toxicity for host cells

Which of the following can be considered a method of disinfection?

  • Autoclaving materials at appropriate times and temperature
  • Applying Neosporin® to a cut on the skin
  • Using UV radiation to kill microorganisms
  • Spraying a surface with 70% ethanol (correct)

What is the primary use of an antiseptic?

<p>To disinfect wounds and mucous membranes (D)</p> Signup and view all the answers

Which of the following is an example of a disinfectant?

<p>Spraying a surface with 70% ethanol (B)</p> Signup and view all the answers

Which method of sterilization uses ethylene oxide or formaldehyde gases?

<p>Autoclaves (C)</p> Signup and view all the answers

Which method of sterilization is suitable for organic compounds that would degrade under high temperatures?

<p>Filtration (C)</p> Signup and view all the answers

Which method is recommended for items that cannot be sterilized or are noncritical items?

<p>Barrier protection (A)</p> Signup and view all the answers

What are the microorganisms of concern in dental unit waterlines?

<p>All of the above (D)</p> Signup and view all the answers

Which of the following is a primary source of microorganisms in dental unit waterlines?

<p>Municipal water supply (D)</p> Signup and view all the answers

How long should water and air be discharged after each patient from any device connected to the dental water system?

<p>20-30 seconds (C)</p> Signup and view all the answers

Which agency regulates disinfectants and sterilants?

<p>EPA (C)</p> Signup and view all the answers

Which agency regulates antiseptics?

<p>FDA (B)</p> Signup and view all the answers

What are the ideal properties of a disinfectant?

<p>Non-toxic to humans (A)</p> Signup and view all the answers

What are the ideal properties of an antiseptic?

<p>Active against a broad spectrum of pathogens (A)</p> Signup and view all the answers

What can be done to test the water quality in dental units?

<p>All of the above (D)</p> Signup and view all the answers

Which of the following is NOT an ideal property of a disinfectant?

<p>Toxic to humans (A)</p> Signup and view all the answers

Which agency is responsible for regulating antiseptics?

<p>Food and Drug Administration (FDA) (B)</p> Signup and view all the answers

Which of the following is NOT an ideal property of a disinfectant?

<p>Toxic to humans (B)</p> Signup and view all the answers

Which of the following is an ideal property of an antiseptic?

<p>Non-staining (B)</p> Signup and view all the answers

Which of the following is an ideal property of an antiseptic?

<p>High therapeutic index with the ability to kill -cidal and limit -static growth of organism. (D)</p> Signup and view all the answers

What is the recommended concentration for disinfection of blood spills with sodium hypochlorite?

<p>1:10 (B)</p> Signup and view all the answers

Which of the following is a characteristic of iodine as an antiseptic?

<p>Bactericidal in 1 minute and kills spores in 15 minutes (D)</p> Signup and view all the answers

Which method is recommended for disinfection or sterilization of instruments especially those that cannot withstand high temperatures?

<p>Aldehydes (C)</p> Signup and view all the answers

Which of the following is a potential side effect of using iodine as an antiseptic?

<p>Hypersensitivity reactions (B)</p> Signup and view all the answers

What is the recommended dilution for sodium hypochlorite as a disinfectant?

<p>1:10 (B)</p> Signup and view all the answers

Which of the following materials are bleach solutions corrosive to?

<p>Aluminum, silver, and stainless steel (B)</p> Signup and view all the answers

What is the primary function of halogens and halogen-releasing compounds as antiseptics?

<p>Denaturing proteins and nucleic acids (A)</p> Signup and view all the answers

What is the main function of superoxidized water as a disinfectant?

<p>To denature proteins and nucleic acids (B)</p> Signup and view all the answers

What can accelerate the decomposition rate of chlorine in superoxidized water?

<p>Sunlight exposure (B)</p> Signup and view all the answers

What is the contact time required for achieving a high level of disinfection with superoxidized water?

<p>10 minutes (B)</p> Signup and view all the answers

Which compound forms crosslinks in proteins and nucleic acids, and can act in alkylation of proteins?

<p>Aldehydes (B)</p> Signup and view all the answers

What is the recommended use of superoxidized water in dental settings?

<p>Removal of bacteria from dental water lines (D)</p> Signup and view all the answers

What can cause failures of disinfection with aldehydes?

<p>All of the above (D)</p> Signup and view all the answers

What is the stability period of superoxidized water when stored correctly?

<p>14 days (C)</p> Signup and view all the answers

Which of the following is NOT a recommended use of alcohol-based hand rubs?

<p>Sterilant (A)</p> Signup and view all the answers

What is the recommended method to increase penetration of aldehydes into devices for disinfection?

<p>Use of closed, circulating baths, with longer contact time (A)</p> Signup and view all the answers

Which compound is a bisphenol and has been used in toothpastes and soaps?

<p>Triclosan (D)</p> Signup and view all the answers

Which of the following is a phenolic-related compound still used as a disinfectant?

<p>o-phenylphenol (A)</p> Signup and view all the answers

What is the primary use of aldehydes as disinfectants or sterilants?

<p>Disinfection of dental instruments (D)</p> Signup and view all the answers

Which of the following compounds can disrupt cell walls and membranes, denature and inactivate enzymes?

<p>Phenol (D)</p> Signup and view all the answers

Which compound has corrosive effects on the tissues, high toxicity through the skin, and has carcinogenic effects?

<p>Phenol (C)</p> Signup and view all the answers

Which of the following is a recommended concentration for alcohol-based hand rubs?

<p>60-90% (C)</p> Signup and view all the answers

Which of the following compounds is derived from coal tar distillates and is used in Lysol?

<p>Xylenols and Cresol (A)</p> Signup and view all the answers

Which of the following is true about hydrogen peroxide (H2O2)?

<p>All of the above (D)</p> Signup and view all the answers

Which of the following is NOT a recommended method for disinfection or sterilization of instruments?

<p>Alcohol-based hand rubs (D)</p> Signup and view all the answers

Which of the following is a property of alcohols as antiseptics and disinfectants?

<p>They denature proteins and precipitate nucleic acids and cause membrane damage (B)</p> Signup and view all the answers

Which of the following is true about alcohol-based hand rubs and C. difficile spores?

<p>Alcohol-based hand rubs have no effect on C. difficile spores. (A)</p> Signup and view all the answers

Which of the following compounds should not be used in nurseries or near infants due to an association with hyperbilirubinemia?

<p>Phenol (D)</p> Signup and view all the answers

Which of the following is true about the activity of hydrogen peroxide (H2O2) on bacteria?

<p>H2O2 has greater activity on Gram-positive bacteria. (A)</p> Signup and view all the answers

Which of the following is true about the mechanism of action of hydrogen peroxide (H2O2) on bacteria?

<p>H2O2 acts as an oxidant. (D)</p> Signup and view all the answers

Which of the following is true about the activity of biguanides?

<p>Biguanides have a low irritation and broad spectrum of activity. (C)</p> Signup and view all the answers

Which of the following is true about the preferred agent for skin antisepsis in many surgical procedures?

<p>The preferred agent is chlorhexidine. (C)</p> Signup and view all the answers

Which of the following is true about the binding of chlorhexidine to bacterial cell walls?

<p>Chlorhexidine binds to negatively charged bacterial cell walls. (C)</p> Signup and view all the answers

Which of the following is true about the use of biguanides in mouthwash?

<p>Biguanides help reduce plaque and improve mild gingivitis. (D)</p> Signup and view all the answers

Which of the following is true about the activity of chlorhexidine?

<p>Chlorhexidine has a long persistent activity on the skin. (B)</p> Signup and view all the answers

Which of the following is true about the combination of chlorhexidine and alcohol?

<p>The combination enhances the activity of chlorhexidine. (C)</p> Signup and view all the answers

Which plant extract is used as a local anesthetic and has counterirritant qualities?

<p>Menthol (C)</p> Signup and view all the answers

What is the mechanism of action of heavy metals like mercury and silver as disinfectants?

<p>Reactions on thiol containing proteins (C)</p> Signup and view all the answers

Which compound is used as a preservative in certain vaccines, antitoxins, and immune sera?

<p>Thimerosal (C)</p> Signup and view all the answers

Which surfactant classification includes items such as soaps and detergents?

<p>Anionic surfactants (D)</p> Signup and view all the answers

What happens when cationic and anionic surfactants are mixed together?

<p>They precipitate out of solution (D)</p> Signup and view all the answers

What is the mechanism of action for surfactants as disinfectants?

<p>Cause microbial membrane disruption (A)</p> Signup and view all the answers

What classification does cetylpyridium chloride belong to?

<p>Cationic surfactants (D)</p> Signup and view all the answers

What is the primary source of eucalyptol?

<p>Eucalyptus plant (D)</p> Signup and view all the answers

What is the role of monoterpenes in plant oils?

<p>Cause membrane instability and promote the leakage of intracellular materials (C)</p> Signup and view all the answers

Which of the following is the primary use of silver nitrate in newborns?

<p>To prevent gonococcal ophthalmitis (C)</p> Signup and view all the answers

What can limit the efficacy of disinfectants and antiseptics?

<p>Intrinsic and acquired bacterial resistance mechanisms (C)</p> Signup and view all the answers

What is an example of an intrinsic bacterial resistance mechanism?

<p>Change in the outer membrane to prevent chemical penetration (B)</p> Signup and view all the answers

What is an example of an acquired bacterial resistance mechanism?

<p>Uptake of a plasmid encoding for an efflux pump (B)</p> Signup and view all the answers

What can help improve the overall efficacy of disinfectants and antiseptics?

<p>Proper testing and combinational treatments (D)</p> Signup and view all the answers

What is the primary use of silver sulfadiazine?

<p>To suppress bacterial growth in burn wounds (D)</p> Signup and view all the answers

What are the ideal properties of a disinfectant or antiseptic?

<p>Non-toxic to humans (B)</p> Signup and view all the answers

What can microbes develop resistance to?

<p>Disinfectants and antiseptics (D)</p> Signup and view all the answers

What determines the use of a disinfectant or antiseptic?

<p>The clinical use (D)</p> Signup and view all the answers

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