Stem Cells and Differentiation Concepts

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Questions and Answers

What distinguishes unipotent cells from non-stem cells?

  • Their capacity for self-renewal. (correct)
  • Their inability to produce any mature cells.
  • Their ability to differentiate into multiple cell types.
  • Their origin from embryonic tissues.

Which type of stem cell is derived from the blastocyst stage of development?

  • Multipotent stem cells
  • Embryonic stem cells (correct)
  • Amniotic fluid stem cells
  • Induced pluripotent stem cells

Which of the following correctly describes multipotent hematopoietic stem cells?

  • They produce cells of a closely-related family, like blood cells. (correct)
  • They can only produce red blood cells.
  • They cannot self-renew.
  • They can differentiate into any cell type in the body.

What process is used to create induced pluripotent stem cells from adult somatic cells?

<p>Dedifferentiation (B)</p> Signup and view all the answers

Which type of stem cell is typically considered as multipotent, capable of producing a limited number of cell types?

<p>Adult stem cells (D)</p> Signup and view all the answers

What describes the process of cell differentiation?

<p>The process of unspecialized cells acquiring specialized features. (D)</p> Signup and view all the answers

What is one key property of stem cells?

<p>They possess self-renewal ability. (A)</p> Signup and view all the answers

Which type of stem cell has the potential to form a complete organism?

<p>Totipotent stem cells. (A)</p> Signup and view all the answers

Which of the following best describes pluripotent stem cells?

<p>They can give rise to nearly all cell types. (B)</p> Signup and view all the answers

What term describes the ability of stem cells to produce a stem cell and a progenitor cell?

<p>Asymmetric division. (B)</p> Signup and view all the answers

Which of the following statements is true about the cells in adult animals?

<p>Adult cells are often found in the GO stage of the cell cycle. (A)</p> Signup and view all the answers

What best describes the potency of stem cells?

<p>Their capacity to differentiate into multiple cell types. (C)</p> Signup and view all the answers

Which type of stem cells are derived from the inner cell mass of the blastocyst?

<p>Pluripotent stem cells. (D)</p> Signup and view all the answers

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Study Notes

Cell Proliferation

  • Adult cells have different proliferation rates, some actively divide while others are arrested in the G0 phase

Cell Differentiation

  • Unspecialized cells acquire specific structural and functional characteristics during differentiation
  • This process leads to the development of specialized cells, tissues, and organs in mature organisms

Stem Cells

  • Early development involves rapid proliferation and differentiation of embryonic cells
  • Stem cells retain the ability to divide and produce differentiated cell types

Stem Cell Properties

  • Self-renewal: Stem cells maintain their undifferentiated state while dividing
  • Potency: Stem cells have the capacity to differentiate into multiple cell lineages

Types of Stem Cells

  • Totipotent stem cells: Found in early embryos, can generate all cell types and tissues
  • Pluripotent stem cells: Derived from the inner cell mass of the blastocyst, can differentiate into the three primary germ layers (ectoderm, mesoderm, endoderm)
  • Multipotent stem cells: Can produce cells of a closely related family, like hematopoietic stem cells
  • Unipotent cells: Can produce only one type of mature cell but retain self-renewal properties

Sources of Stem Cells

  • Embryonic stem cells: Pluripotent stem cells derived from blastocysts, ethical restrictions limit their use
  • Adult stem cells: Multipotent stem cells found in adult tissues, can only produce a limited number of cell types
  • Amniotic fluid stem cells: Multipotent stem cells
  • Umbilical cord blood stem cells: Considered pluripotent
  • Induced pluripotent stem cells: Created by reprogramming adult somatic cells to acquire embryonic stem cell properties

Therapeutic Applications of Stem Cells

  • Stem cells hold potential for treating various diseases and injuries by:
    • Replacing damaged or lost cells
    • Regenerating tissues
    • Repairing organs
    • Developing potential treatments for conditions like:
      • Cancer
      • Neurological disorders
      • Heart disease
      • Diabetes
      • Spinal cord injuries

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