30 Questions
What is the main goal of targeting cancer stem cells according to the cancer stem cell hypothesis?
To prevent cancer recurrence
Which of the following is NOT an application of stem cell research?
Creating genetically modified organisms
What type of stem cells are responsible for maintaining tissue homeostasis?
Tissue-specific stem cells
What is the main advantage of using pluripotent stem cells in drug discovery?
They can differentiate into any cell type
What is the main concern with unproven stem cell procedures?
They are not evidence-based
What is the main goal of regenerative medicine using stem cells?
To stimulate cells and tissues to re-grow or repair
What is the primary characteristic of pluripotent stem cells that distinguishes them from tissue-specific stem cells?
Ability to differentiate into multiple cell types
What is the role of tissue-specific stem cells in tissue homeostasis?
To maintain tissue health and function
What is a concern regarding the clinical application of emerging stem cell therapies?
They have not been proven to be safe and effective
What is a characteristic of symmetric self-renewal cell division in stem cells?
Producing two identical daughter cells
What is a key difference between pluripotent stem cells and tissue-specific stem cells?
Ability to differentiate into multiple cell types
What is the main issue with unproven stem cell procedures?
They have not been tested for safety and efficacy
What percentage of completed trials had published results?
46%
What percentage of trials reported positive outcomes?
63.7%
What is a characteristic of pluripotent stem cells?
They can generate any cell type of the body.
Why is it important for patients to be educated about stem cell tourism?
So they can make informed decisions about unproven treatments.
What is the purpose of the International Society for Stem Cell Research?
To provide information to help patients evaluate stem cell treatment claims.
What is a concern about stem cell tourism clinics?
None of them have reported results.
What is the primary limitation of using tissue-restricted stem cells for treatment?
They can only make one or a few specialized cell types
What is the timeframe for generating and purifying differentiated cell types of interest?
1 to 3 months
What is a characteristic of pluripotent stem cells?
They can make all the cells in the body
What characteristic do tissue-specific stem cells typically exhibit?
Extensive proliferative potential
What is a concern with commercial provision of unproven stem cell therapies?
Lack of regulation
What is the primary role of the stem cell niche in tissue homeostasis?
To regulate the stem cell behavior
Why are induced pluripotent stem cells considered a promising treatment option for acute injuries?
They are not suitable for acute injuries, such as spinal injury
What is a key feature distinguishing pluripotent stem cells from tissue-specific stem cells?
Ability to generate cells of multiple tissues
What is the approximate frequency of hematopoietic stem cells in bone marrow cells?
1 in 100,000
What is a potential application of stem cell research in ocular therapies?
Treatment of both adult and childhood cataracts
What is a principle guiding the clinical application of human pluripotent stem cells?
The 3R principle
What is the primary role of tissue-specific stem cells in maintaining tissue homeostasis?
To maintain tissue homeostasis
This quiz tests your knowledge of stem cell properties, including their proliferative capacity and ability to differentiate into various cell types. It also covers their applications in treating injuries and diseases. Learn about the characteristics of pluripotent stem cells and their potential uses.
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