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Questions and Answers
What is the primary therapeutic use of statins?
What is the primary therapeutic use of statins?
Which mechanism describes how statins work in the body?
Which mechanism describes how statins work in the body?
Which of the following is a common adverse reaction associated with statin use?
Which of the following is a common adverse reaction associated with statin use?
What should patients avoid while taking Mevacor (lovastatin)?
What should patients avoid while taking Mevacor (lovastatin)?
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What is the common dosing schedule for statins?
What is the common dosing schedule for statins?
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What is the primary action of statins in cholesterol synthesis?
What is the primary action of statins in cholesterol synthesis?
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Which of the following statements about statins is true regarding their dosing?
Which of the following statements about statins is true regarding their dosing?
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What is a potential serious adverse effect of statin use?
What is a potential serious adverse effect of statin use?
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Which statin is known to require the avoidance of antacids containing magnesium?
Which statin is known to require the avoidance of antacids containing magnesium?
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Which enzyme's activity do statins specifically inhibit?
Which enzyme's activity do statins specifically inhibit?
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Which statement accurately describes a characteristic of statins?
Which statement accurately describes a characteristic of statins?
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What is a notable risk associated with the side effects of statins?
What is a notable risk associated with the side effects of statins?
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Which of the following is NOT a common adverse reaction of statins?
Which of the following is NOT a common adverse reaction of statins?
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What should patients taking Lipitor (atorvastatin) avoid in their diet to prevent adverse reactions?
What should patients taking Lipitor (atorvastatin) avoid in their diet to prevent adverse reactions?
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Which of the following statins is available in multiple dosage forms including extended release?
Which of the following statins is available in multiple dosage forms including extended release?
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Which of the following statins is available in a dosage of 80mg?
Which of the following statins is available in a dosage of 80mg?
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What is a common adverse reaction that may occur with statin use?
What is a common adverse reaction that may occur with statin use?
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What is the common suffix used in the names of statin medications?
What is the common suffix used in the names of statin medications?
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Which of the following mechanisms describes how statins contribute to cholesterol management?
Which of the following mechanisms describes how statins contribute to cholesterol management?
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Which of the following could be a proper labeling for patients using Lipitor (atorvastatin)?
Which of the following could be a proper labeling for patients using Lipitor (atorvastatin)?
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Match the statin with its brand name:
Match the statin with its brand name:
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Match the statin with its common adverse reaction:
Match the statin with its common adverse reaction:
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Match the statin with its available dosage forms:
Match the statin with its available dosage forms:
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Match the statin with what to avoid while taking it:
Match the statin with what to avoid while taking it:
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Match the following HMG CoA Reductase Inhibitors with their mechanism of action:
Match the following HMG CoA Reductase Inhibitors with their mechanism of action:
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Match the following statins with their corresponding generic names:
Match the following statins with their corresponding generic names:
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Match the following statins with their common auxiliary label:
Match the following statins with their common auxiliary label:
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Match the following adverse reactions with the correct description:
Match the following adverse reactions with the correct description:
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Match the following statins with their available dosage forms:
Match the following statins with their available dosage forms:
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Match the following statins with their commonly used to treat conditions:
Match the following statins with their commonly used to treat conditions:
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Statins are indicated primarily for the treatment of hypertension.
Statins are indicated primarily for the treatment of hypertension.
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The generic name for Crestor is pravastatin.
The generic name for Crestor is pravastatin.
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All statins share the common suffix '-statin'.
All statins share the common suffix '-statin'.
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Rhabdomyolysis is a common adverse reaction associated with statin use.
Rhabdomyolysis is a common adverse reaction associated with statin use.
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Statins work by enhancing the activity of HMG CoA reductase.
Statins work by enhancing the activity of HMG CoA reductase.
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Statins are primarily used to treat hyperlipidemia.
Statins are primarily used to treat hyperlipidemia.
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All statins are available in a dosage of 80mg.
All statins are available in a dosage of 80mg.
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Muscle cramps are a potential adverse reaction of statin use.
Muscle cramps are a potential adverse reaction of statin use.
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Statins increase the activity of HMG CoA reductase in cholesterol synthesis.
Statins increase the activity of HMG CoA reductase in cholesterol synthesis.
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Patients taking Lipitor should avoid eating grapefruit.
Patients taking Lipitor should avoid eating grapefruit.
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Statins are commonly used to treat hyperlipidemia.
Statins are commonly used to treat hyperlipidemia.
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The common ending for statin medications is '-statin'.
The common ending for statin medications is '-statin'.
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Rhabdomyolysis is a rare adverse reaction associated with statin use.
Rhabdomyolysis is a rare adverse reaction associated with statin use.
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Statins work by stimulating the activity of HMG CoA reductase.
Statins work by stimulating the activity of HMG CoA reductase.
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Patients taking Mevacor should avoid grapefruit.
Patients taking Mevacor should avoid grapefruit.
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Study Notes
Statin Drugs
- Therapeutic Class: HMG CoA Reductase Inhibitors
- Common Name: Statins
- Common Ending: -statin
- Commonly Used to Treat: Hyperlipidemia (high cholesterol)
-
Mechanism of Action:
- Enzymes that end in -ase are involved
- HMG CoA Reductase are enzymes involved in cholesterol synthesis
- Statins inhibit HMG CoA reductase
- Inhibit final step in cholesterol synthesis
- Also increases the clearance of LDL (low-density lipoproteins, "lousy" cholesterol)
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Notes:
- Usually administered once daily, typically in the evening or at bedtime.
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Common Adverse Reactions:
- Myositis (inflammation of muscle)
- Rhabdomyolysis (breakdown of muscle tissue)
- Muscle cramps/pain
- Liver dysfunction
- Brand Name | Generic Name | Available Doses & Forms | Auxiliary Label(s)
- --|---|---|--- Crestor | rosuvastatin | Tablets - 5mg, 10mg, 20mg, 40mg | Avoid antacids containing magnesium Lescol | fluvastatin | Capsules - 20mg, 40mg; Extended Release Tablets - 80mg | Avoid grapefruit Lipitor | atorvastatin | Tablets - 10mg, 20mg, 40mg, 80mg | Avoid grapefruit Mevacor | lovastatin | Tablets - 20mg, 40mg | Avoid grapefruit Pravachol | pravastatin | Tablets - 10mg, 20mg, 40mg | Avoid grapefruit Zocor | simvastatin | Tablets - 5mg, 10mg, 20mg, 40mg, 80mg | Avoid grapefruit
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Description
This quiz covers the therapeutic class of statin drugs, their mechanism of action, common uses, and potential adverse reactions. Learn the key details about HMG CoA reductase inhibitors and their role in treating hyperlipidemia. Test your knowledge on various statin medications and their specifics.
