Stages of Alcoholic Liver Disease Quiz
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Questions and Answers

What is the primary characteristic of cholestasis in alcoholic liver disease?

  • Pre-conjugation failure
  • Increased B2 with hepatic pigmentation (correct)
  • Increased hepatic excretion of bilirubin
  • Decreased uptake of bilirubin
  • Which enzyme is a sensitive indicator of ethanol intake?

  • Aminotransferases
  • Alkaline phosphatase
  • Gamma-glutamyl transferase (correct)
  • Cholinesterase
  • Which enzyme values are reliable for monitoring hepatitis progression according to the text?

  • Alkaline phosphatase
  • Aminotransferases (ALT/AST) (correct)
  • Lactate dehydrogenase
  • Gamma-glutamyl transferase
  • What is the characteristic change in cholinesterase levels in liver disorders?

    <p>Values decrease</p> Signup and view all the answers

    What does lactate dehydrogenase elevation indicate according to the text?

    <p>Liver disease</p> Signup and view all the answers

    Which enzyme is primarily elevated in an obstructive process in liver disorders?

    <p>Alkaline phosphatase</p> Signup and view all the answers

    Which method of bilirubin determination follows the principle of Evelyn Malloy?

    <p>MICROBILIRUBIN</p> Signup and view all the answers

    What is the calculated value for DELTA BILIRUBIN?

    <p>$TB-DB+IB$</p> Signup and view all the answers

    Which enzyme helps in monitoring the decline of serum bilirubin following surgical removal of gallstones?

    <p>Cholinesterase</p> Signup and view all the answers

    Which enzyme is not calculated on neonatal patients (< 14 days)?

    <p>Gamma-glutamyl transferase</p> Signup and view all the answers

    Which enzyme reacts with diazo reagents in the direct bilirubin assay?

    <p>Gamma-glutamyl transferase</p> Signup and view all the answers

    What type of bilirubin is increased in hepatic jaundice?

    <p>Both free and conjugated bilirubin</p> Signup and view all the answers

    Which syndrome is characterized by absence of UDPGT enzyme?

    <p>Crigler-Najjar syndrome Type I</p> Signup and view all the answers

    Which inherited disorder presents with impaired excretion of bilirubin from hepatocytes?

    <p>Dubin-Johnson syndrome</p> Signup and view all the answers

    What is the main cause of obstructive or cholestatic jaundice?

    <p>Biliary stricture</p> Signup and view all the answers

    Which condition is associated with a severe increase in lactate dehydrogenase (LDH) levels?

    <p>Crigler-Najjar syndrome Type I</p> Signup and view all the answers

    Which enzyme deficiency leads to a survival to adulthood in Crigler-Najjar syndrome Type 2?

    <p>Increased conjugating enzyme</p> Signup and view all the answers

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