Podcast
Questions and Answers
What is the primary function of the protein produced by the Sst gene?
What is the primary function of the protein produced by the Sst gene?
- To stimulate growth hormone release
- To promote cell proliferation
- To increase thyroid-stimulating hormone secretion
- To regulate the endocrine system as a hormone called somatostatin (correct)
Somatostatin stimulates the release of insulin and glucagon.
Somatostatin stimulates the release of insulin and glucagon.
False (B)
Name two locations in the body where somatostatin is produced.
Name two locations in the body where somatostatin is produced.
hypothalamus, brain, digestive system
Somatostatin exerts its effects by binding to __________.
Somatostatin exerts its effects by binding to __________.
Match the hormone with the effect somatostatin has on its release:
Match the hormone with the effect somatostatin has on its release:
Which chromosome is the Sst gene located on?
Which chromosome is the Sst gene located on?
Mutations in the Sst gene have no significant impact on hormone regulation.
Mutations in the Sst gene have no significant impact on hormone regulation.
Besides hormone regulation, what other bodily function does somatostatin affect in the brain?
Besides hormone regulation, what other bodily function does somatostatin affect in the brain?
What is the incredibly rare outcome of complete Sst gene knockout in vivo?
What is the incredibly rare outcome of complete Sst gene knockout in vivo?
Somatostatin plays a critical role in controlling growth, metabolism, and __________.
Somatostatin plays a critical role in controlling growth, metabolism, and __________.
Flashcards
What is the Sst gene?
What is the Sst gene?
A gene providing instructions for somatostatin production.
What is somatostatin?
What is somatostatin?
A hormone that regulates the endocrine system.
Where is somatostatin produced?
Where is somatostatin produced?
Hypothalamus, brain, and digestive system.
How does somatostatin work?
How does somatostatin work?
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What hormones does somatostatin inhibit?
What hormones does somatostatin inhibit?
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What body functions does somatostatin control?
What body functions does somatostatin control?
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Where is the Sst gene located?
Where is the Sst gene located?
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What can Sst gene mutations cause?
What can Sst gene mutations cause?
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How does Somatostatin act as a neurotransmitter?
How does Somatostatin act as a neurotransmitter?
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How does Somatostatin regulate blood sugar?
How does Somatostatin regulate blood sugar?
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Study Notes
- Sst is a gene that provides instructions for making somatostatin protein.
- Somatostatin is a hormone that regulates the endocrine system, impacting neurotransmission and cell proliferation.
- Specialized hypothalamus cells, as well as other brain and digestive system cells produce Somatostatin.
- Somatostatin functions through binding to somatostatin receptors.
- Numerous other hormones are inhibited by Somatostatin, including growth hormone, thyroid-stimulating hormone, insulin, and glucagon.
- Somatostatin regulates hormone release, and controls various body functions, including growth, metabolism, and digestion.
- The Sst gene is located on chromosome 3 at position 3q27-q28.
- Mutations in the Sst gene can result in hormone dysregulation.
- Growth hormone secretion is inhibited by somatostatin.
- Thyroid-stimulating hormone (TSH) secretion is also inhibited by somatostatin.
- Blood sugar levels are regulated by somatostatin through the inhibition of insulin and glucagon release.
- In the brain, somatostatin acts as a neurotransmitter, influencing neuronal activity.
- Somatostatin has the ability to inhibit cell proliferation in certain cell types.
- Somatostatin has a role in regulating the endocrine system.
- Somatostatin affects neurotransmission in the brain.
- The regulation of cell proliferation involves somatostatin.
- Somatostatin exerts its effects by binding to somatostatin receptors.
- The hypothalamus contains specialized cells that produce somatostatin.
- Other cells in the brain and digestive system also contribute to somatostatin production.
- The release of growth hormone is suppressed by somatostatin.
- Somatostatin inhibits the release of thyroid-stimulating hormone.
- Insulin release is inhibited by somatostatin.
- Somatostatin inhibits the release of glucagon.
- Growth is regulated by somatostatin.
- Somatostatin helps regulate metabolism.
- The control of digestion involves somatostatin.
- The Sst gene is found on chromosome 3.
- Mutations of the Sst gene can lead to hormone dysregulation.
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