Podcast
Questions and Answers
What is a prevalent condition associated with the enlargement of bones in extremities and viscera?
What is a prevalent condition associated with the enlargement of bones in extremities and viscera?
- Gigantism
- Rickets
- Dawarfism (correct)
- Osteoporosis
Which treatment is suitable for excess growth hormone (GH) conditions?
Which treatment is suitable for excess growth hormone (GH) conditions?
- Surgery
- Hormone replacement therapy
- Octreotide & Lanreotide (correct)
- Physical therapy
What is one of the primary hormones stimulated by ghrelin?
What is one of the primary hormones stimulated by ghrelin?
- Cortisol
- Growth hormone (correct)
- Adrenaline
- Insulin
What physiological effect is primarily mediated by IGF-1?
What physiological effect is primarily mediated by IGF-1?
What condition is characterized by genetic factors leading to effects on growth?
What condition is characterized by genetic factors leading to effects on growth?
What is the primary effect of growth hormone (GH) stimulation in children?
What is the primary effect of growth hormone (GH) stimulation in children?
Which of the following describes a direct effect of growth hormone?
Which of the following describes a direct effect of growth hormone?
What happens in the treatment of Dawarfism?
What happens in the treatment of Dawarfism?
Which option is NOT a direct effect of growth hormone?
Which option is NOT a direct effect of growth hormone?
What role does insulin-like growth factor-1 (IGF-1) play in the body?
What role does insulin-like growth factor-1 (IGF-1) play in the body?
What is the primary function of growth hormone inhibiting hormone (GHIH)?
What is the primary function of growth hormone inhibiting hormone (GHIH)?
Which hormone release is NOT inhibited by GHIH?
Which hormone release is NOT inhibited by GHIH?
What is a synthetic analog of somatostatin?
What is a synthetic analog of somatostatin?
What is a major difference between GHIH and its synthetic analog, Octreotide?
What is a major difference between GHIH and its synthetic analog, Octreotide?
Which of the following hormones does GHIH inhibit that is related to digestive functions?
Which of the following hormones does GHIH inhibit that is related to digestive functions?
What is the primary function of Thyroid-Stimulating Hormone (TSH)?
What is the primary function of Thyroid-Stimulating Hormone (TSH)?
Which hormone is known to directly inhibit the receptor it binds to?
Which hormone is known to directly inhibit the receptor it binds to?
Which of the following is NOT a role of Thyroid-Stimulating Hormone (TSH)?
Which of the following is NOT a role of Thyroid-Stimulating Hormone (TSH)?
What could be a likely effect of elevated Thyroid-Stimulating Hormone (TSH) levels?
What could be a likely effect of elevated Thyroid-Stimulating Hormone (TSH) levels?
Which hormone specifically prompts growth in the thyroid gland?
Which hormone specifically prompts growth in the thyroid gland?
What does an increase in plasma thyroid hormone levels indicate?
What does an increase in plasma thyroid hormone levels indicate?
Which of the following indicates thyroid insufficiency?
Which of the following indicates thyroid insufficiency?
What is the relationship between plasma thyroid hormone levels after stimulation and pituitary function?
What is the relationship between plasma thyroid hormone levels after stimulation and pituitary function?
What condition is associated with elevated levels of thyroid hormones due to a secondary issue?
What condition is associated with elevated levels of thyroid hormones due to a secondary issue?
In the context of thyroid hormone stimulation, what does a lack of increase in hormone levels suggest?
In the context of thyroid hormone stimulation, what does a lack of increase in hormone levels suggest?
Flashcards are hidden until you start studying
Study Notes
Growth Hormone Inhibiting Hormone (GHIH, Somatostatin)
- Inhibits the release of growth hormone.
- Also inhibits the release of glucagon, gastrin, and thyrotrophin.
- Octreotide, a synthetic analog of somatostatin, has a longer half-life than the natural compound.
- Ghrelin stimulates the secretion of growth hormone.
Physiological Effects of Growth Hormone
- Direct effects:
- Stimulates the secretion of insulin-like growth factor 1 (IGF-1).
- Stimulates lipolysis.
- Increases blood glucose levels.
- Indirect effects mediated primarily by IGF-1:
- Promote the growth of long bones.
- Enlargement of bones in extremities (hands, feet, jaw, and nose) and visceral organs.
Growth Hormone Agonists and Antagonists
Agonists
- Treatment of dwarfism.
- Stimulation of growth in children with Turner's syndrome (a genetic disorder affecting growth).
Antagonists
- Treatment of excess growth hormone.
- Octreotide & Lanreotide (long-acting preparations): inhibit GH secretion.
- Pegvisomant: blocks the GH receptor itself.
Thyroid-Stimulating Hormone (Thyrotropin, TSH)
- Stimulates the growth of the thyroid gland.
- A rise in plasma thyroid hormone levels indicates abnormal pituitary function, while no rise indicates thyroid insufficiency.
- Increased thyroid hormone levels after stimulation suggest a pituitary gland dysfunction (secondary hypothyroidism).
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
