SSRI Side Effects Quiz

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Which class of antidepressants is chemically related to TCAs and is claimed to have fewer side effects and less toxicity in overdose?

SSRIs

Atypical antidepressants (correct)

SNRIs

MAOIs

Which class of antidepressants sometimes works in patients who were unresponsive to TCAs or SSRIs, but is not more efficacious nor faster-acting than other antidepressants?

Lithium

MAOIs

Atypical antidepressants (correct)

SNRIs

Which of the following side effects is NOT commonly associated with SSRIs?

Tremors

Drowsiness

Photosensitivity (correct)

Akathisia

Which neurotransmitter reuptake do some atypical antidepressants affect?

Norepinephrine Signup and view all the answers

Which class of drugs is lithium used as a prophylactic against mood swings in bipolar depression?

Mood stabilizers Signup and view all the answers

What mechanism of action does lithium primarily interfere with?

Cyclic AMP production Signup and view all the answers

What is the main reason MAOIs are rarely used?

They have severe food interactions leading to hypertensive response Signup and view all the answers

What is the main side effect associated with an increase in monoamines due to MAOIs?

Hypotension Signup and view all the answers

When do the antidepressant effects of MAOIs typically start to develop?

After 3-4 weeks of treatment Signup and view all the answers

What is the 'cheese reaction' associated with MAOIs?

Hypertensive response due to dietary tyramine intake Signup and view all the answers

Why are MAOIs considered a last line of defense in antidepressant treatment?

Severe food and drug interactions Signup and view all the answers

What CNS-related side effect can occur in overdose with MAOIs?

Convulsions Signup and view all the answers

Which class of drugs are SSRIs a part of?

Selective serotonin reuptake inhibitors Signup and view all the answers

What is the typical half-life range of most SSRIs?

18-24 hours Signup and view all the answers

Which side effect of SSRIs tends to occur later in treatment but may improve with time?

Sexual side effects Signup and view all the answers

What dangerous complication may arise when SSRIs interact with MAOI antidepressants?

Serotonin syndrome Signup and view all the answers

Why are Paroxetine and fluoxetine not used in combination with TCAs?

They increase TCA toxicity by inhibiting their metabolism Signup and view all the answers

Apart from depression and anxiety, which condition is commonly treated with SSRIs?

Obsessive-compulsive disorder Signup and view all the answers