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Questions and Answers
Which property of muscle tissue describes its ability to respond to nerve signals?
Which property of muscle tissue describes its ability to respond to nerve signals?
What is the primary function of skeletal muscle tissue?
What is the primary function of skeletal muscle tissue?
Which type of muscle tissue is characterized as striated and under voluntary control?
Which type of muscle tissue is characterized as striated and under voluntary control?
Which characteristic of skeletal muscle is indicated by having multiple nuclei within its fibers?
Which characteristic of skeletal muscle is indicated by having multiple nuclei within its fibers?
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What is the role of muscle tissue in thermogenesis?
What is the role of muscle tissue in thermogenesis?
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Which type of muscle fiber organization is characterized by a branched tendon with muscle fibers arranged around each branch?
Which type of muscle fiber organization is characterized by a branched tendon with muscle fibers arranged around each branch?
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Which of the following describes a muscle that reduces the diameter of openings in the body?
Which of the following describes a muscle that reduces the diameter of openings in the body?
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Which classification refers to muscles named based on their location in the body?
Which classification refers to muscles named based on their location in the body?
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In a biceps curl, which muscles act as synergists to help stabilize the joint and assist in movement?
In a biceps curl, which muscles act as synergists to help stabilize the joint and assist in movement?
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What is the role of fixator muscles during movement?
What is the role of fixator muscles during movement?
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Which muscle classification is based on the number of heads of origin?
Which muscle classification is based on the number of heads of origin?
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What is the main action performed by agonist muscles during movement?
What is the main action performed by agonist muscles during movement?
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Which attribute characterizes the muscle named 'gluteus maximus'?
Which attribute characterizes the muscle named 'gluteus maximus'?
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Which term refers to a muscle that opposes the action of agonists?
Which term refers to a muscle that opposes the action of agonists?
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What characteristic is associated with nuclei in skeletal muscle fibers?
What characteristic is associated with nuclei in skeletal muscle fibers?
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Which connective tissue component surrounds individual muscle fibers?
Which connective tissue component surrounds individual muscle fibers?
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What type of muscle attachment typically remains fixed during contraction?
What type of muscle attachment typically remains fixed during contraction?
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Which of the following correctly describes the speed of contraction in skeletal muscle?
Which of the following correctly describes the speed of contraction in skeletal muscle?
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What is the primary neurotransmitter that regulates contractions in skeletal muscle?
What is the primary neurotransmitter that regulates contractions in skeletal muscle?
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Which muscle organization type has fibers that run parallel to the length of the muscle?
Which muscle organization type has fibers that run parallel to the length of the muscle?
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Which connective tissue component helps to support muscles and connects them to bones?
Which connective tissue component helps to support muscles and connects them to bones?
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What is the role of the rotator cuff in relation to movement?
What is the role of the rotator cuff in relation to movement?
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Which connective tissue sheath surrounds the entire muscle?
Which connective tissue sheath surrounds the entire muscle?
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What is the function of the T-tubules in muscle cells?
What is the function of the T-tubules in muscle cells?
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How are myofibrils organized within muscle fibers?
How are myofibrils organized within muscle fibers?
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What distinguishes the A Band from the I Band in myofibrils?
What distinguishes the A Band from the I Band in myofibrils?
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What type of muscles are characterized as involuntary and non-striated?
What type of muscles are characterized as involuntary and non-striated?
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What component surrounds each individual muscle fiber?
What component surrounds each individual muscle fiber?
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Which structure is primarily responsible for storing calcium in muscle cells?
Which structure is primarily responsible for storing calcium in muscle cells?
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What distinguishes thick myofilaments from thin myofilaments?
What distinguishes thick myofilaments from thin myofilaments?
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Study Notes
Muscle Tissue Overview
- Muscle tissue is specialized for contraction, producing voluntary or involuntary body part movement.
- It is one of the basic tissues in the body.
- Muscle cells (fibers/myocytes) are elongated and narrow.
- "Sarco" is Greek for muscle; "Myo" is Latin for muscle. These prefixes are used in describing muscle.
Properties of Muscle Tissue
- Excitability: Responds to nerve signals by generating electrical signals.
- Contractility: Shortens and generates force.
- Extensibility: Can be stretched.
- Elasticity: Returns to its original shape.
Functions of Muscle Tissue
- Movement.
- Maintaining posture.
- Stabilizing joints.
- Thermogenesis (transforming chemical energy to mechanical energy, thus creating force).
- Increasing muscle mass, boosting the immune system.
Types of Muscle Tissue
- Skeletal muscle
- Smooth muscle
- Cardiac muscle
Skeletal Muscle
- Connects to bones via tendons, enabling a wide range of movements and functions.
- It is the most common and abundant muscle type.
- It is striated and under voluntary control.
- Examples include muscles in the limbs and body wall.
Characteristics of Skeletal Muscle
- Microscopic: Long cylindrical fibers (muscle cells/myocytes), cross-striations, multiple nuclei (peripherally distributed), and unbranched.
- Location: Attached to bones via tendons.
- Nervous Control: Voluntary, supplied by somatic nerves, governed by the somatic nervous system.
- Speed of Contraction: Fast.
- Size: Very large (10-100 µm diameter, up to 35 cm length).
- Connective Tissue Components: Endomysium, perimysium, epimysium.
- Contractile Proteins: Organized into sarcomeres.
- Junctions/Rhythmicity: No junctions between muscle fibers, no auto-rhythmicity.
- Regulator Proteins: Troponin and Tropomyosin; regulate contraction.
Parts of a Muscle
- Belly: The fleshy part of the muscle.
- Tendons: Fibrous parts, tightly connected to the bones or cartilage. More collagen fibers, less vascular, non-elastic.
- Aponeurosis: Thin fibrous connective tissue sheets that connect muscles to bones and provide stability and strength, especially in flat muscles like abdominal aponeurosis.
Attachments of Muscles
- Origin: Relatively fixed attachment point during muscle contraction; generally located proximally (closer to the center of the body).
- Insertion: Attachment that moves during muscle contraction; generally located distally (further from the center of the body).
Muscle Organization (Arrangement of Muscle Fibers)
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Parallel Muscles: Muscle fibers run parallel to the muscle's length. This is the most common type in the skeletal muscles. Examples of different parallel muscles include: fusiform, strap, and quadrilateral muscles, including the biceps brachii, sartorius, and pronator quadratus.
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Convergent Muscles: Muscle fibers spread out like a fan at one end and converge to a single point at the other, like the pectoralis major.
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Pennate Muscles: Muscle fibers are arranged at an angle to the tendon like a feather. Include different types: unipennate (e.g., palmar interossei), bipennate (e.g., dorsal interossei) and multipennate (e.g., deltoid).
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Circular Muscles: Muscle fibers arranged concentrically around an opening, such as the orbicularis oculi and orbicularis oris.
Nomenclature of Muscles
- Shape, Size, Origin, Number of Heads, Location.
Actions of Skeletal Muscles
- Agonist (Prime Mover): Muscle primarily responsible for a specific movement; directly brings about the intended movement.
- Antagonist: Muscle opposing the action of the agonist.
- Synergist: Muscle assisting the agonist to perform its action, stabilizing the joint during the movement.
- Fixator: Stabilizes proximal joints to allow distal joint movement; a body part stabilizer during a movement of another part; example includes rotator cuff muscles during biceps curl.
Skeletal Muscle Structure
- Surrounded by epimysium (connective tissue).
- Composed of bundles of muscle fibers called fascicles, encased by perimysium.
- Individual muscle fibers have endomysium, a connective tissue sheath.
Skeletal Muscle Fiber Structure
- Contains myofibrils, bundles of contractile proteins.
- Myofibrils are composed of numerous sarcomeres, functional units of contraction.
- Sarcomeres are divided by Z lines.
- Myofilaments: Actin (thin) and Myosin (thick), making up sarcomeres.
- Striations: The overlap pattern of thick and thin filaments creates the striped appearance of skeletal muscles.
- T tubules: Membrane invaginations.
- Sarcolemma: Plasma membrane of the muscle fiber.
- Sarcoplasmic reticulum: Smooth endoplasmic reticulum that stores calcium.
Smooth Muscle
- Involuntary, non-striated muscle, fusiform shape, single, centrally located nucleus.
- Located in the skin (arrector pili muscles), reproductive/respiratory/urinary tracts, hollow organs (e.g., intestines, bladder, uterus, stomach), vessels (blood vessels), and eyes (iris contraction/dilation and lens movement).
Characteristics of Smooth Muscle
- Elongated, spindle-shaped cells.
- Centrally located nucleus.
- Absence of striations, myofibrils, sarcomeres, and T tubules.
- Supplied by autonomic nerves, involuntary.
- Small size (3-8 µm diameter).
- Only endomysium connective tissue component.
- Gap junctions in visceral smooth muscle.
- Auto-rhythmicity of visceral smooth muscle.
- Slow speed of contraction.
Smooth Muscle Structure
- Filaments (thick myosin, thin actin).
- Dense bodies (similar to Z disks in striated muscle), which link filaments and transmits the contractile forces.
Cardiac Muscle
- Involuntary, striated muscle.
- Exclusively in the heart (myocardium).
- Muscle fibers branch and interconnect, forming a network.
- Muscle fibers are short, branched, cylindrical.
- Cells (cardiomyocytes) connected by intercalated disks (allow communication and rapid signal transmission)
- Contains large mitochondria.
- Contains prominent transverse striations.
- Moderate speed of contraction.
- Contains troponin and tropomyosin regulator proteins.
Diseases of the Muscle Tissue
- Myasthenia Gravis: Neuromuscular disorder; weakness in skeletal muscles, caused by communication impairment between nerve cells and muscles. Autoimmune; antibodies attack components of the postsynaptic membrane, impairing neuromuscular transmission.
- Duchenne Muscular Dystrophy: Progressive weakening and loss of skeletal and heart muscle, genetic disorder arising from a mutation in the dystrophin gene.
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