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Questions and Answers
What is the main function of the spleen as a secondary lymphoid organ?
What is the main function of the spleen as a secondary lymphoid organ?
Which process does the spleen undergo as a blood filter?
Which process does the spleen undergo as a blood filter?
What is the structure that surrounds the spleen?
What is the structure that surrounds the spleen?
In what state does the spleen act as a blood store?
In what state does the spleen act as a blood store?
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Which cells mainly make up the white splenic pulp?
Which cells mainly make up the white splenic pulp?
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What forms the framework of the spleen, enveloped by reticular cells?
What forms the framework of the spleen, enveloped by reticular cells?
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Which zone of the spleen is formed by reticular fibers and cells, occupied by specialized B cells and macrophages?
Which zone of the spleen is formed by reticular fibers and cells, occupied by specialized B cells and macrophages?
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What is the main function of the macrophages in the splenic cords?
What is the main function of the macrophages in the splenic cords?
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Which type of circulation theory involves capillaries opening in the splenic cords?
Which type of circulation theory involves capillaries opening in the splenic cords?
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What do the venous sinuses flow into?
What do the venous sinuses flow into?
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Where are the lymphoid follicles mainly made up of B cells located?
Where are the lymphoid follicles mainly made up of B cells located?
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What is the characteristic of the venous sinuses' basement membrane?
What is the characteristic of the venous sinuses' basement membrane?
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Which cells form the periarterial lymphoid sheaths and lymphoid follicles of the white splenic pulp?
Which cells form the periarterial lymphoid sheaths and lymphoid follicles of the white splenic pulp?
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What cells are found in the transition zone between white and red splenic pulp?
What cells are found in the transition zone between white and red splenic pulp?
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Which structures form the hilum of the spleen, where arteries, veins, lymphatics, and nerves enter?
Which structures form the hilum of the spleen, where arteries, veins, lymphatics, and nerves enter?
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What do central and follicular arteries supply in the spleen?
What do central and follicular arteries supply in the spleen?
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Which of the following is NOT a major function of the spleen as a secondary lymphoid organ?
Which of the following is NOT a major function of the spleen as a secondary lymphoid organ?
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What is the name of the parenchyma of the spleen that presents a pulpy appearance when cut?
What is the name of the parenchyma of the spleen that presents a pulpy appearance when cut?
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In what state does the spleen act as a blood filter?
In what state does the spleen act as a blood filter?
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What is the name of the capsule that surrounds the spleen?
What is the name of the capsule that surrounds the spleen?
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What type of cells mainly make up the splenic cords?
What type of cells mainly make up the splenic cords?
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Which theory of splenic circulation involves a combination of both closed and open circulation?
Which theory of splenic circulation involves a combination of both closed and open circulation?
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What type of cells form the framework of the spleen, enveloped by reticular cells?
What type of cells form the framework of the spleen, enveloped by reticular cells?
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What is the characteristic of the venous sinuses' basement membrane?
What is the characteristic of the venous sinuses' basement membrane?
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Where are the lymphoid follicles mainly made up of B cells located?
Where are the lymphoid follicles mainly made up of B cells located?
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Which structures form the hilum of the spleen, where arteries, veins, lymphatics, and nerves enter?
Which structures form the hilum of the spleen, where arteries, veins, lymphatics, and nerves enter?
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In what state does the spleen act as a blood store?
In what state does the spleen act as a blood store?
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What do central and follicular arteries supply in the spleen?
What do central and follicular arteries supply in the spleen?
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What is the main function of the spleen as a secondary lymphoid organ?
What is the main function of the spleen as a secondary lymphoid organ?
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What process does the spleen undergo as a blood filter?
What process does the spleen undergo as a blood filter?
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Which type of circulation theory involves capillaries opening in the splenic cords?
Which type of circulation theory involves capillaries opening in the splenic cords?
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What cells are found in the transition zone between white and red splenic pulp?
What cells are found in the transition zone between white and red splenic pulp?
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Study Notes
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Spleen capsule lined by mesothelium thickened in hilum, where arteries, veins, lymphatics, and nerves enter
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Trabeculae made up of fibroblasts, collagen fibers, elastic fibers, and smooth muscle fibers
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Collagen fibers of trabeculae continued with reticular fibers, forming the framework of the spleen, enveloped by reticular cells
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White splenic pulp: periarterial lymphoid sheaths and lymphoid follicles (Malpighian corpuscles), made up mainly of T cells
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Lymphoid follicles, made up of B cells, follicular dendritic cells, and macrophages, can proliferate and displace central artery, becoming eccentric or follicular artery
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Central and follicular arteries emit collaterals and supply lymphoid structures
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Capillaries, both simple and sheathed, flow into venous sinuses, made up of rounded endothelial cells, discontinuous basement membrane, and reticular cells
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Venous sinuses flow into pulp veins, which drain into trabecular veins and form splenic vein
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Splenic cords surround venous sinuses and are mainly made up of macrophages, which carry out haemocatheretic function in red splenic pulp
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Marginal zone: a transition zone between white and red splenic pulp, formed by reticular fibers and cells, occupied by specialized B cells and macrophages
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Three theories on splenic circulation: closed circulation (all capillaries flow into venous sinuses), open circulation (capillaries open in splenic cords), and modified open circulation (a combination of both)
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The text includes several figures to illustrate the described structures and processes.
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Spleen capsule lined by mesothelium thickened in hilum, where arteries, veins, lymphatics, and nerves enter
-
Trabeculae made up of fibroblasts, collagen fibers, elastic fibers, and smooth muscle fibers
-
Collagen fibers of trabeculae continued with reticular fibers, forming the framework of the spleen, enveloped by reticular cells
-
White splenic pulp: periarterial lymphoid sheaths and lymphoid follicles (Malpighian corpuscles), made up mainly of T cells
-
Lymphoid follicles, made up of B cells, follicular dendritic cells, and macrophages, can proliferate and displace central artery, becoming eccentric or follicular artery
-
Central and follicular arteries emit collaterals and supply lymphoid structures
-
Capillaries, both simple and sheathed, flow into venous sinuses, made up of rounded endothelial cells, discontinuous basement membrane, and reticular cells
-
Venous sinuses flow into pulp veins, which drain into trabecular veins and form splenic vein
-
Splenic cords surround venous sinuses and are mainly made up of macrophages, which carry out haemocatheretic function in red splenic pulp
-
Marginal zone: a transition zone between white and red splenic pulp, formed by reticular fibers and cells, occupied by specialized B cells and macrophages
-
Three theories on splenic circulation: closed circulation (all capillaries flow into venous sinuses), open circulation (capillaries open in splenic cords), and modified open circulation (a combination of both)
-
The text includes several figures to illustrate the described structures and processes.
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Description
Learn about the functions of the spleen as a secondary lymphoid organ, including its roles in hematopoiesis, hemocatheresis, immune response, and blood filtration.
