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Questions and Answers
What is the main function of the spleen as a secondary lymphoid organ?
What is the main function of the spleen as a secondary lymphoid organ?
- Immune function (correct)
- Haemocatheretic function
- Mechanical function
- Haematopoietic function
Which process does the spleen undergo as a blood filter?
Which process does the spleen undergo as a blood filter?
- Storage of blood in stress or disease states
- Production of leukocytes and platelets
- Formation and maturation of red blood cells
- Destruction of blood cells (correct)
What is the structure that surrounds the spleen?
What is the structure that surrounds the spleen?
- Reticular fibers
- Parenchyma
- Pulp
- Stroma (correct)
In what state does the spleen act as a blood store?
In what state does the spleen act as a blood store?
Which cells mainly make up the white splenic pulp?
Which cells mainly make up the white splenic pulp?
What forms the framework of the spleen, enveloped by reticular cells?
What forms the framework of the spleen, enveloped by reticular cells?
Which zone of the spleen is formed by reticular fibers and cells, occupied by specialized B cells and macrophages?
Which zone of the spleen is formed by reticular fibers and cells, occupied by specialized B cells and macrophages?
What is the main function of the macrophages in the splenic cords?
What is the main function of the macrophages in the splenic cords?
Which type of circulation theory involves capillaries opening in the splenic cords?
Which type of circulation theory involves capillaries opening in the splenic cords?
What do the venous sinuses flow into?
What do the venous sinuses flow into?
Where are the lymphoid follicles mainly made up of B cells located?
Where are the lymphoid follicles mainly made up of B cells located?
What is the characteristic of the venous sinuses' basement membrane?
What is the characteristic of the venous sinuses' basement membrane?
Which cells form the periarterial lymphoid sheaths and lymphoid follicles of the white splenic pulp?
Which cells form the periarterial lymphoid sheaths and lymphoid follicles of the white splenic pulp?
What cells are found in the transition zone between white and red splenic pulp?
What cells are found in the transition zone between white and red splenic pulp?
Which structures form the hilum of the spleen, where arteries, veins, lymphatics, and nerves enter?
Which structures form the hilum of the spleen, where arteries, veins, lymphatics, and nerves enter?
What do central and follicular arteries supply in the spleen?
What do central and follicular arteries supply in the spleen?
Which of the following is NOT a major function of the spleen as a secondary lymphoid organ?
Which of the following is NOT a major function of the spleen as a secondary lymphoid organ?
What is the name of the parenchyma of the spleen that presents a pulpy appearance when cut?
What is the name of the parenchyma of the spleen that presents a pulpy appearance when cut?
In what state does the spleen act as a blood filter?
In what state does the spleen act as a blood filter?
What is the name of the capsule that surrounds the spleen?
What is the name of the capsule that surrounds the spleen?
What type of cells mainly make up the splenic cords?
What type of cells mainly make up the splenic cords?
Which theory of splenic circulation involves a combination of both closed and open circulation?
Which theory of splenic circulation involves a combination of both closed and open circulation?
What type of cells form the framework of the spleen, enveloped by reticular cells?
What type of cells form the framework of the spleen, enveloped by reticular cells?
What is the characteristic of the venous sinuses' basement membrane?
What is the characteristic of the venous sinuses' basement membrane?
Where are the lymphoid follicles mainly made up of B cells located?
Where are the lymphoid follicles mainly made up of B cells located?
Which structures form the hilum of the spleen, where arteries, veins, lymphatics, and nerves enter?
Which structures form the hilum of the spleen, where arteries, veins, lymphatics, and nerves enter?
In what state does the spleen act as a blood store?
In what state does the spleen act as a blood store?
What do central and follicular arteries supply in the spleen?
What do central and follicular arteries supply in the spleen?
What is the main function of the spleen as a secondary lymphoid organ?
What is the main function of the spleen as a secondary lymphoid organ?
What process does the spleen undergo as a blood filter?
What process does the spleen undergo as a blood filter?
Which type of circulation theory involves capillaries opening in the splenic cords?
Which type of circulation theory involves capillaries opening in the splenic cords?
What cells are found in the transition zone between white and red splenic pulp?
What cells are found in the transition zone between white and red splenic pulp?
Study Notes
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Spleen capsule lined by mesothelium thickened in hilum, where arteries, veins, lymphatics, and nerves enter
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Trabeculae made up of fibroblasts, collagen fibers, elastic fibers, and smooth muscle fibers
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Collagen fibers of trabeculae continued with reticular fibers, forming the framework of the spleen, enveloped by reticular cells
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White splenic pulp: periarterial lymphoid sheaths and lymphoid follicles (Malpighian corpuscles), made up mainly of T cells
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Lymphoid follicles, made up of B cells, follicular dendritic cells, and macrophages, can proliferate and displace central artery, becoming eccentric or follicular artery
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Central and follicular arteries emit collaterals and supply lymphoid structures
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Capillaries, both simple and sheathed, flow into venous sinuses, made up of rounded endothelial cells, discontinuous basement membrane, and reticular cells
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Venous sinuses flow into pulp veins, which drain into trabecular veins and form splenic vein
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Splenic cords surround venous sinuses and are mainly made up of macrophages, which carry out haemocatheretic function in red splenic pulp
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Marginal zone: a transition zone between white and red splenic pulp, formed by reticular fibers and cells, occupied by specialized B cells and macrophages
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Three theories on splenic circulation: closed circulation (all capillaries flow into venous sinuses), open circulation (capillaries open in splenic cords), and modified open circulation (a combination of both)
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The text includes several figures to illustrate the described structures and processes.
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Spleen capsule lined by mesothelium thickened in hilum, where arteries, veins, lymphatics, and nerves enter
-
Trabeculae made up of fibroblasts, collagen fibers, elastic fibers, and smooth muscle fibers
-
Collagen fibers of trabeculae continued with reticular fibers, forming the framework of the spleen, enveloped by reticular cells
-
White splenic pulp: periarterial lymphoid sheaths and lymphoid follicles (Malpighian corpuscles), made up mainly of T cells
-
Lymphoid follicles, made up of B cells, follicular dendritic cells, and macrophages, can proliferate and displace central artery, becoming eccentric or follicular artery
-
Central and follicular arteries emit collaterals and supply lymphoid structures
-
Capillaries, both simple and sheathed, flow into venous sinuses, made up of rounded endothelial cells, discontinuous basement membrane, and reticular cells
-
Venous sinuses flow into pulp veins, which drain into trabecular veins and form splenic vein
-
Splenic cords surround venous sinuses and are mainly made up of macrophages, which carry out haemocatheretic function in red splenic pulp
-
Marginal zone: a transition zone between white and red splenic pulp, formed by reticular fibers and cells, occupied by specialized B cells and macrophages
-
Three theories on splenic circulation: closed circulation (all capillaries flow into venous sinuses), open circulation (capillaries open in splenic cords), and modified open circulation (a combination of both)
-
The text includes several figures to illustrate the described structures and processes.
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Description
Learn about the functions of the spleen as a secondary lymphoid organ, including its roles in hematopoiesis, hemocatheresis, immune response, and blood filtration.
