Histology of Immune System: Spleen Structure and Function

Give rise to capillaries

Two routes: closed circulation and open circulation

Splenic sinusoids

<p>Sinusoids</p> Signup and view all the answers

<p>The primary function of the spleen in the immune process is filtration of blood, destruction of old erythrocytes, and production of antibodies and activated lymphocytes.</p> Signup and view all the answers

<p>Splenic vein</p> Signup and view all the answers

<p>The spleen is composed of reticular tissue, which contains reticular cells and fibers, lymphocytes, macrophages, and antigen-presenting cells. Its two main components are the white pulp, which constitutes 20% of the spleen, and the red pulp, which makes up the rest of the spleen.</p> Signup and view all the answers

<p>The periarteriolar lymphoid sheath (PALS) is composed mainly of T lymphocytes, macrophages, and plasma cells that surround the central arterioles in the white pulp. The PALS is responsible for initiating immune responses.</p> Signup and view all the answers

<p>The blood circulation in the spleen involves the hilum, where arteries and nerves enter the spleen and veins leave the organ. The blood circulation in the spleen can be classified into two types: the open circulation and the closed circulation.</p> Signup and view all the answers

<p>The spleen is surrounded by a dense connective tissue capsule, from which trabeculae penetrate the organ. This capsule provides support and stability to the spleen, allowing it to maintain its structure and function effectively.</p> Signup and view all the answers