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Histology of Immune System: Spleen Structure and Function

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Histology of Immune System: Spleen Structure and Function

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Questions and Answers

What is the role of central arterioles within the white pulp of the spleen?

Give rise to capillaries

Describe the blood flow in the red pulp of the spleen.

Two routes: closed circulation and open circulation

What separates the splenic cords (of Billroth) within the red pulp of the spleen?

Splenic sinusoids

Where do red pulp veins collect blood from in the spleen?

Sinusoids Signup and view all the answers

What is the primary function of the spleen in the immune process?

The primary function of the spleen in the immune process is filtration of blood, destruction of old erythrocytes, and production of antibodies and activated lymphocytes. Signup and view all the answers

What is the final vein formed by the convergence of trabecular veins in the spleen?

Splenic vein Signup and view all the answers

Describe the structural composition of the spleen, including its two main components.

The spleen is composed of reticular tissue, which contains reticular cells and fibers, lymphocytes, macrophages, and antigen-presenting cells. Its two main components are the white pulp, which constitutes 20% of the spleen, and the red pulp, which makes up the rest of the spleen. Signup and view all the answers

Explain the role and composition of the periarteriolar lymphoid sheath (PALS) in the white pulp.

The periarteriolar lymphoid sheath (PALS) is composed mainly of T lymphocytes, macrophages, and plasma cells that surround the central arterioles in the white pulp. The PALS is responsible for initiating immune responses. Signup and view all the answers

Describe the blood circulation in the spleen, and classify its types.

The blood circulation in the spleen involves the hilum, where arteries and nerves enter the spleen and veins leave the organ. The blood circulation in the spleen can be classified into two types: the open circulation and the closed circulation. Signup and view all the answers

How does the spleen's dense connective tissue capsule contribute to its overall structure and function?

The spleen is surrounded by a dense connective tissue capsule, from which trabeculae penetrate the organ. This capsule provides support and stability to the spleen, allowing it to maintain its structure and function effectively. Signup and view all the answers