Splanchnic Circulation Overview

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Questions and Answers

What primarily causes left-sided heart failure?

  • Cardiomyopathy from genetic factors
  • Right ventricular overload
  • High blood pressure only
  • Coronary artery disease leading to myocardial infarction (correct)

Which of the following is NOT a compensatory mechanism associated with heart failure?

  • Increase in aldosterone secretion
  • Enhanced cardiac output (correct)
  • Decrease in glomerular filtration
  • Activation of the Renin-angiotensin system

What is a primary effect of heart failure on the circulatory system?

  • Damming of blood in the veins (correct)
  • Stabilization of blood pressure
  • Reduction in peripheral vascular resistance
  • Increased cardiac output

What condition can increase the pressure in pulmonary veins as a result of left-sided heart failure?

<p>Pulmonary venous distention (D)</p> Signup and view all the answers

Which factor directly causes peripheral edema in patients with heart failure?

<p>Decreased glomerular filtration (D)</p> Signup and view all the answers

What does the activation of the Renin-angiotensin system lead to in the context of heart failure?

<p>Increased aldosterone secretion (B)</p> Signup and view all the answers

Which characteristic is associated with the muscles of the heart in heart failure?

<p>They become weakened and damaged. (D)</p> Signup and view all the answers

Which of the following conditions is a common result of left-sided heart failure?

<p>Pulmonary congestion leading to cough (C)</p> Signup and view all the answers

Which artery is NOT part of the splanchnic circulation system?

<p>Pulmonary artery (A)</p> Signup and view all the answers

What regulates splanchnic perfusion during stressful conditions?

<p>Neurogenic regulation (D)</p> Signup and view all the answers

Which of the following factors is considered an intrinsic mechanism influencing splanchnic circulation?

<p>Local hormones (C)</p> Signup and view all the answers

In the context of the lungs, which circulation does NOT contribute to the lung's blood flow?

<p>Lymphatic circulation (D)</p> Signup and view all the answers

Which part of the circulation is responsible for nourishing the trachea and distal bronchioles?

<p>Bronchial arteries (A)</p> Signup and view all the answers

What percentage of cardiac output is received by the splanchnic circulation?

<p>25-35% (D)</p> Signup and view all the answers

The major arteries supplying splanchnic organs are arranged in which manner?

<p>Parallel (B)</p> Signup and view all the answers

What is the primary function of the pulmonary capillary bed?

<p>Oxygenating blood (A)</p> Signup and view all the answers

Flashcards

What is the splanchnic circulation?

The splanchnic circulation consists of blood vessels supplying the digestive organs including the stomach, small intestine, colon, pancreas, liver, and spleen. These circulations are arranged in parallel, meaning they operate independently.

What are the main arteries supplying the splanchnic organs?

The three major arteries supplying the splanchnic organs are the celiac artery, superior mesenteric artery, and inferior mesenteric artery. These arteries branch out and connect extensively, forming a complex network.

What factors influence the splanchnic circulation?

The splanchnic circulation is influenced by factors outside (extrinsic) and inside (intrinsic) the digestive system. Extrinsic factors include systemic blood pressure, the autonomic nervous system, and circulating hormones. Intrinsic factors include the properties of blood vessels themselves, local chemicals, and local nerve signals.

How much blood does the splanchnic circulation receive?

The splanchnic circulation receives a significant portion of the heart's output, around 25-35%. This flow is regulated by autoregulation, neurogenic factors, and humoral factors.

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How is blood flow regulated in the splanchnic circulation?

Autoregulation ensures that blood flow in the splanchnic organs adjusts to their metabolic needs, meaning more blood flows when organs are actively digesting.

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What are the two types of blood flow in the lungs?

The pulmonary circulation carries deoxygenated blood from the heart to the lungs for oxygenation and then returns oxygenated blood to the heart. The bronchial circulation supplies blood to the airways and surrounding tissues.

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How does blood flow through the pulmonary circulation?

In the pulmonary circulation, the pulmonary arteries branch alongside the bronchi, delivering deoxygenated blood to the capillaries in the lungs. The oxygenated blood is then returned to the heart through the pulmonary veins, which run between the bronchi.

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What is the bronchial circulation and how does it work?

The bronchial circulation arises from systemic arteries, supplying blood to the airways, pleura, and lymph nodes. The blood is drained back into the systemic circulation via bronchial veins, merging into the azygos vein.

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Heart Failure

A condition in which the heart is unable to pump blood effectively, leading to inadequate blood supply to the body.

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Cor Pulmonale

A type of heart failure primarily affecting the right ventricle, often caused by lung conditions.

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Cardiomyopathy

Damage to the heart muscle caused by conditions like infections, alcohol abuse, or drug abuse, contributing to heart failure.

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Compensatory Mechanisms in Heart Failure

A mechanism that compensates for reduced cardiac output in heart failure by activating the Renin-Angiotensin system and increasing aldosterone secretion to help retain fluids.

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Peripheral Edema in Heart Failure

Fluid buildup in the tissues, particularly in the lower extremities, due to inadequate blood flow.

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Left-Sided Heart Failure

The failure of the left ventricle, causing increased pressure in the pulmonary veins and fluid buildup in the lungs.

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Pulmonary Congestion

A condition characterized by fluid buildup in the air spaces of the lungs due to increased pressure in the pulmonary veins, leading to shortness of breath and coughing.

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Lymphatic System in the Lungs

The lymphatic system plays a key role in the lungs, with more lymphatic channels present compared to other organs. Lymph nodes are arranged along the bronchial tree, filtering lymph and facilitating unidirectional flow toward the subclavian veins.

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Study Notes

Splanchnic Circulation

  • The splanchnic circulation includes gastric, small intestinal, colonic, pancreatic, hepatic, and splenic circulations, arranged in parallel.
  • The celiac, superior, and inferior mesenteric arteries supply the splanchnic organs, branching into smaller arteries that extensively anastomose.
  • Some splanchnic organs have an intramural circulation.
  • Splanchnic circulation is influenced by extrinsic and intrinsic factors.
  • Extrinsic factors include general hemodynamic conditions, the autonomic nervous system, and circulating neurohumoral agents.
  • Intrinsic factors include the vasculature's properties, local metabolites, intrinsic nerves, paracrine substances, and local hormones.

Splanchnic Circulation - Blood and Lymph

  • 25-35% of cardiac output goes to splanchnic circulation.
  • Splanchnic perfusion is regulated via autoregulation, neurogenic, and humoral regulation.
  • The pulmonary circulation and bronchial circulation contribute to blood flow in the lungs.
  • Blood in the pulmonary circulation travels to the pulmonary capillaries for oxygenation, returning to the left atrium via pulmonary veins.
  • Pulmonary arteries branch according to bronchi, while pulmonary veins are spaced between bronchi.
  • Bronchial circulation includes bronchial arteries nourishing trachea and terminal bronchioles and surrounding structures.

Heart Failure

  • Heart failure occurs when the heart pump's ability to meet body's blood flow needs decreases.
  • It can involve the right or left ventricle or both.
  • Heart failure can be caused by coronary artery disease, cardiomyopathy, or conditions overworking the heart (e.g., high blood pressure, valve disease, thyroid disease).
  • Symptoms include shortness of breath with activity or when lying down, tiredness, swelling in the legs, feet, irregular heartbeat, reduced exercise tolerance, persistent cough, white/pink mucus or blood spots,and/or belly swelling.

Causes of Peripheral Edema in Heart Failure

  • Decreased glomerular filtration
  • Activation of renin-angiotensin system
  • Increased aldosterone secretion
  • Weakened heart muscle's inability to pump sufficient blood flow.

Right-Sided Heart Failure

  • Right-sided heart failure is caused by right ventricle failure.
  • It leads to increased venous pressure, fluid transudation, edema, ascites, hepatomegaly, difficulty with portal flow.

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