Spinal Cord Lesions and Syndromes
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Questions and Answers

A patient presents with hyperreflexia, a positive Babinski sign, and bowel/bladder dysfunction. Where would you suspect the lesion is located?

  • Cerebellum
  • Muscle
  • Lower motor neuron
  • Upper motor neuron pathway below the lesion (correct)

A patient has lost pain and temperature sensation on the right side of the body and motor control on the left side of the body. What spinal cord syndrome is most likely?

  • Syringomyelia
  • Posterior cord syndrome
  • Anterior cord syndrome
  • Brown-Séquard syndrome (correct)

Which of the following is NOT a typical characteristic feature of spinal cord disease?

  • Upper motor neuron findings below the lesion
  • Presence of lower motor neuron findings below the lesion (correct)
  • Sensory and motor involvement localizing to a specific spinal cord level
  • Bowel and bladder dysfunction

A patient experiences loss of pain and temperature sensation in a 'cape-like' distribution over the shoulders and upper back. Which condition is most likely?

<p>Syringomyelia (A)</p> Signup and view all the answers

Why is it clinically important to know that the spinal cord typically ends around the L1-L2 vertebral level?

<p>It helps differentiate between spinal cord lesions and cauda equina syndrome. (C)</p> Signup and view all the answers

A patient presents with loss of pain and temperature sensation on the right side of their body, starting two levels below the site of injury, and weakness on the left side. Which condition is MOST likely?

<p>Brown-Sequard syndrome (A)</p> Signup and view all the answers

In Brown-Sequard syndrome, which of the following sensory deficits would be observed ipsilateral to the lesion?

<p>Loss of vibration and proprioception (D)</p> Signup and view all the answers

A patient has an intramedullary astrocytoma resulting in Brown-Sequard syndrome. What is the MOST likely mechanism causing their motor deficits?

<p>Compression of the lateral corticospinal tract (A)</p> Signup and view all the answers

Damage to the spinothalamic tract causes loss of pain and temperature sensation on the contralateral side, starting one or two levels below the injury. What anatomical feature explains this?

<p>The axons in the spinothalamic tract cross the midline 1-2 segments above their entry point into the spinal cord. (B)</p> Signup and view all the answers

A patient exhibits upper motor neuron signs, loss of pain and temperature sensation on their right side, and loss of vibration sense on their left side. Where is the MOST likely location of the lesion?

<p>Left hemisection of the spinal cord (B)</p> Signup and view all the answers

In Brown-Séquard syndrome, a lesion affecting the right side of the spinal cord would most likely result in which sensory deficit?

<p>Loss of pain and temperature sensation on the left side of the body a few levels below the lesion. (B)</p> Signup and view all the answers

Why does the loss of pain and temperature sensation occur a few levels below the lesion in Brown-Séquard syndrome?

<p>The anterolateral spinothalamic tract ascends ipsilaterally several segments before decussating. (A)</p> Signup and view all the answers

A patient with Brown-Séquard syndrome exhibits paralysis on one side of their body. Which descending tract is most likely affected to cause this?

<p>Lateral corticospinal tract (A)</p> Signup and view all the answers

In Brown-Séquard syndrome, what sensory function is affected ipsilaterally due to involvement of the dorsal column?

<p>Proprioception (D)</p> Signup and view all the answers

Which combination of deficits would most likely be observed in a patient with Brown-Séquard syndrome affecting the left side of the spinal cord at the T10 level?

<p>Ipsilateral loss of proprioception below T10, contralateral loss of pain/temperature sensation below T12, ipsilateral paralysis below T10. (C)</p> Signup and view all the answers

A patient presents with weakness in their hands and legs, but retains strength in the proximal muscles of their arms. Where is the MOST likely location of the spinal cord lesion?

<p>Lower cervical spinal cord (C)</p> Signup and view all the answers

A patient has complete paralysis of the lower extremities after a traumatic injury. This condition is BEST described as:

<p>Paraplegia (C)</p> Signup and view all the answers

After a spinal cord injury, a patient exhibits a temporary state of flaccid paralysis, loss of reflexes, and bowel and bladder dysfunction. What is the MOST likely cause of these symptoms?

<p>Spinal shock (A)</p> Signup and view all the answers

A patient with a high cervical spinal cord injury is MOST at risk for which of the following complications?

<p>Impaired respiration (D)</p> Signup and view all the answers

Damage to the spinothalamic tract would MOST likely result in a deficit in which of the following?

<p>Pain and temperature sensation (C)</p> Signup and view all the answers

Which of the following sensory modalities is transmitted via the posterior columns of the spinal cord?

<p>Vibration (D)</p> Signup and view all the answers

A clinician observes the Babinski sign during a neurological examination. This finding suggests damage to which of the following?

<p>Upper motor neurons (A)</p> Signup and view all the answers

A patient reports loss of urinary control (incontinence) and constipation following a spinal cord injury. This presentation is MOST consistent with:

<p>Autonomic nervous system dysfunction. (D)</p> Signup and view all the answers

In Central Cord Syndrome, smaller lesions primarily affect which ascending tract due to the interruption of decussating fibers?

<p>Anterolateral Spinothalamic tract (D)</p> Signup and view all the answers

Larger lesions in Central Cord Syndrome can additionally affect which of the following tracts?

<p>Cuneatus Fasciculus and Lateral Corticospinal tracts (D)</p> Signup and view all the answers

Why are the upper extremities more affected than the lower extremities in Central Cord Syndrome?

<p>Due to the somatotopic organization of spinal tracts, with cervical fibers located more medially. (B)</p> Signup and view all the answers

Which sensory and motor deficits are characteristic of Central Cord Syndrome due to the location of the lesion?

<p>Bilateral loss of discriminative pain and temperature in the upper extremities and superior trunk, with potential motor impairments. (A)</p> Signup and view all the answers

Which spinal cord structure is supplied by the anterior spinal artery?

<p>Anterior two-thirds of the spinal cord (C)</p> Signup and view all the answers

In Central Cord Syndrome, which portions of the body retain function because the periphery of the cord is unaffected?

<p>Thoracic, lumbar, and sacral regions (D)</p> Signup and view all the answers

From which vertebral levels does the Artery of Adamkiewicz typically arise?

<p>T9 to T12 (C)</p> Signup and view all the answers

A patient with Central Cord Syndrome exhibits greater motor weakness in their hands and arms compared to their legs. Which anatomical principle explains this observation?

<p>The somatotopic arrangement within the spinal cord places cervical fibers more centrally. (C)</p> Signup and view all the answers

A patient with Central Cord Syndrome has difficulty distinguishing between sharp and dull sensations on their arms but can still feel these sensations normally on their legs. Which specific spinal tract is most likely affected to cause this?

<p>Anterolateral Spinothalamic tract (C)</p> Signup and view all the answers

What neurological deficits would most likely result from damage to the Artery of Adamkiewicz?

<p>Paraplegia (C)</p> Signup and view all the answers

A patient exhibits loss of discriminative pain and temperature sensation along with paralysis below the level of the lesion, while retaining proprioception and discriminative touch. Which spinal cord syndrome is most likely?

<p>Anterior Cord Syndrome (C)</p> Signup and view all the answers

In a patient diagnosed with Central Cord Syndrome, examination reveals impaired fine touch discrimination in the upper extremities. Which specific pathway is most likely involved?

<p>Cuneatus Fasciculus of the Dorsal Column (D)</p> Signup and view all the answers

Which arteries typically give rise to the posterior spinal arteries?

<p>Vertebral arteries (D)</p> Signup and view all the answers

What sensory modalities are typically preserved in Anterior Cord Syndrome?

<p>Vibration and proprioception (B)</p> Signup and view all the answers

A patient presents with unilateral paralysis, loss of proprioception, and loss of vibration sense on the same side of the body as the spinal cord lesion, along with contralateral loss of pain and temperature sensation. Which spinal cord syndrome is most likely?

<p>Brown-Séquard Syndrome (C)</p> Signup and view all the answers

Which of the following ascending tracts are present in the spinal cord?

<p>Spinothalamic tract (B)</p> Signup and view all the answers

Flashcards

Spinal Cord Lesion Deficits

Damage to the spinal cord can result in specific deficits depending on the location and extent of the lesion.

Anterior Spinal Cord Syndrome

Affects motor function, pain, and temperature sensation, while preserving light touch and proprioception.

Syringomyelia

A condition characterized by fluid-filled cavities within the spinal cord, leading to a cape-like distribution of sensory loss (pain and temperature).

Brown-Séquard Syndrome

Ipsilateral motor and proprioception loss with contralateral pain and temperature loss.

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Features of Spinal Cord Disease

Upper motor neuron signs (hyperreflexia, Babinski sign) below the level of the lesion, sensory and motor involvement at a specific spinal cord level, and bowel/bladder dysfunction.

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Motor Symptoms Below Lesion

Weakness or paralysis occurring below the site of a spinal cord lesion.

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Plegia

Complete paralysis due to a spinal cord injury

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Paresis

Some muscle strength is preserved despite a spinal cord injury.

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Tetraplegia (Quadriplegia)

Injury to the cervical spinal cord, affecting all four limbs. Arms may still have movement if injury is below C5.

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Paraplegia

Injury to the thoracic, lumbo-sacral cord, or cauda equina, affecting the lower limbs.

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Hemiplegia

Paralysis of one half of the body, typically due to brain injuries like stroke.

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Spinal Shock

Flaccid paralysis and loss of autonomic reflexes (if injury above T6), including bowel and bladder dysfunction.

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Neurogenic Bladder

Inability to control bladder function due to a neurological condition, resulting in urgency, incontinence, or retention.

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Dorsal Column Involvement

Loss of proprioception and discriminative touch on the same side of the lesion.

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Anterolateral Spinothalamic Tract Deficit

Loss of crude touch, pain, and temperature sensation on the opposite side, a few levels below the lesion.

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Descending Tract Involvement (Brown-Séquard)

Paralysis on the same side of the lesion.

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Spinothalamic Tract Delay

The anterolateral spinothalamic tract ascends several segments before crossing over.

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Brown-Sequard Syndrome Cause

Cord hemisection, often caused by trauma or tumor.

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Contralateral Sensory Loss in Brown-Sequard

Loss of pain and temperature sensation on the opposite side of the lesion, typically one or two levels below due to the crossing of spinothalamic tracts.

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Ipsilateral Sensory Loss in Brown-Sequard

Loss of vibration and proprioception on the same side as the lesion.

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Ipsilateral Motor Deficits in Brown-Sequard

Weakness and UMN (Upper Motor Neuron) findings on the same side as the spinal cord lesion.

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Spinal Cord Lesion Types

Lesions such as intramedullary astrocytomas, myelitis, or trauma that can affect the spinal cord.

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Anterior Spinal Artery

Formed by vertebral artery branches, it descends the anterior median fissure.

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Posterior Spinal Arteries

Arise from vertebral arteries and descend the posterior spinal cord.

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Artery of Adamkiewicz

Arises from T9-T12, it's a critical radiculomedullary artery.

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Anterior Cord Syndrome Deficits

Discriminative pain and temperature loss + paralysis below lesion level.

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Brown-Sequard Syndrome Deficits

Ipsilateral motor and proprioception loss; contralateral pain and temperature loss.

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Central Cord Syndrome: Limb Impact

Central Cord Syndrome primarily affects the upper extremities more than the lower extremities due to the somatotopic organization of spinal tracts.

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Anterior Cord Syndrome: Impact

An injury resulting in loss of motor function and pain/temperature sensation.

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Brown-Sequard Syndrome: Key Feature

Involves damage to one half of the spinal cord.

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Central Cord Syndrome: Spared Function

The outer regions of the spinal cord are unaffected, resulting in preserved function in the thoracic, lumbar, and sacral regions.

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Central Cord Syndrome: Sensory Loss

Results in bilateral loss of pain and temperature sensation in the upper extremities and superior trunk, due to damage to the Anterolateral Spinothalamic tracts.

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Tracts in Brown-Sequard Syndrome

Includes the lateral corticospinal and spinothalamic tracts.

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Central Cord Syndrome: Large Lesion Effects

Larger lesions may cause loss of discriminative touch and conscious proprioception due to involvement of the cuneatus fasciculus.

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Central Cord Syndrome: Motor Impairment

Motor impairments can occur with larger lesions due to involvement of the lateral corticospinal tracts.

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Central Cord: Small Lesion Impact

Small lesions primarily affect the Anterolateral Spinothalamic tracts due to interruption of decussating fibers, leading to loss of pain and temperature sensation.

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Central Cord: Tracts Affected (Large Lesions)

With larger lesions, the Cuneatus Fasciculus of the Dorsal Column and the medial aspect of the Lateral Corticospinal tracts are affected.

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Spinal Cord Somatotopy

The somatotopic organization of the spinal tracts dictates that cervical fibers are most medial, followed by thoracic, lumbar, and sacral fibers laterally.

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Study Notes

  • Spinal cord injuries result in deficits characteristic of lesions in the anterior, lateral, and posterior columns.
  • Anterior spinal cord syndrome, syringomyelia, and Brown-Séquard syndrome are types of spinal cord injuries.

Clinically Important Ascending Tracts

  • Ascending tracts carry sensory information from the body to the brain.
  • These tracts include those for vibration, position sense, two-point discrimination, touch, pain, and temperature.
  • The primary neuron is in the dorsal root ganglion.
  • The secondary neuron is in the spinal cord.
  • The tertiary neuron is in the thalamus.
  • The somesthetic cortex, located in the postcentral gyrus of the parietal lobe, receives sensory information.

Clinically Important Descending Tracts

  • Descending tracts carry motor information from the brain to the body.
  • The corticobulbar tract crosses (mostly) and uncrossed (some).
  • The lateral corticospinal tract crosses (most) and is uncrossed (some).
  • The somatic motor area is in the precentral gyrus of the frontal lobe

Spinal Cord End

  • The spinal cord typically ends at the L1-L2 vertebral level in adults.
  • Understanding where the spinal cord ends is important for procedures like lumbar punctures, where the needle is inserted below the spinal cord to avoid injury.

Basic Features of Spinal Cord Disease

  • Upper motor neuron (UMN) findings below the lesion, such as hyperreflexia and Babinski's sign, are common.
  • Sensory and motor involvement localizes to a specific spinal cord level.
  • Bowel and bladder dysfunction are common.

UMN vs LMN Differences

  • UMN lesions' etiologies include stroke of the motor strip or internal capsule and spinal cord injury.
  • LMN lesion's etologies include herniated intervertebral disc, nerve entrapment syndrome, and polio

Symptoms below the lesion

  • Plegia is complete loss of muscle function.
  • Paresis is muscle weakness, where some muscle strength is preserved.
  • Tetraplegia (or quadriplegia) is injury to the cervical spinal cord, which can result patient's ability to move their arms using segments above the injury.
  • Paraplegia is injury of the thoracic or lumbo-sacral cord, or cauda equina.
  • Hemiplegia is paralysis of one half of the body, usually in brain injuries like stroke.

Motor Exam

  • Strength testing can localize a spinal cord lesion.
  • Quadriplegia with impaired respiration indicates an upper cervical lesion.
  • Proximal arm strength preserved with hand and leg weakness indicates a lower cervical lesion.
  • Paraplegia indicates a thoracic lesion, but midline brain lesions can also cause paraplegia.
  • Tone: Increased tone is typically found distal to the lesion.

Babinski Sign

  • Defined as UMN syndrome
  • Normal response is downward flexion of the toes
  • Plantar Extensor response shows upward extension of the toes

Sensory Symptoms & Exam

  • Sensory symptoms include changes in pain, temperature, and proprioception.
  • Establishing a sensory level is important, noting dermatomes such as the nipples (T4-5) and umbilicus (T8-9).
  • Posterior column function is assessed through vibration and joint position sense (proprioception) testing.
  • Spinothalamic tracts are assessed by testing pain and temperature sensation.

Spinal Shock

  • Spinal shock is characterized by flaccid paralysis, loss of autonomic reflexes (especially in injuries above T6), and bowel and bladder dysfunction.

Autonomic Disturbances

  • Spinal cord injury can lead to neurogenic bladder.
  • Bowel dysfunction, is typically from constipation rather than incontinence.
  • A high cord lesion can cause loss of blood pressure control and alterations in sweating.

Ascending and Descending Tracts

Central Cord Syndrome (Case Study 1)

  • Small lesions primarily affect the anterolateral spinothalamic tracts due to interruption of decussating fibers.
  • Larger lesions can affect the cuneatus fasciculus of the dorsal column and the medial aspect of the lateral corticospinal tracts.
  • Upper extremities are more affected than lower extremities.
  • Thoracic, lumbar, and sacral functions are typically retained, leading to bilateral loss of discriminative pain and temperature in the upper extremities and superior trunk.
  • Large lesions may cause loss of discriminative touch, conscious proprioception, and motor impairments.

Syringomyelia

  • Fluid-filled cavity (syrinx) forms in the center of the spinal cord.
  • The cervical cord is the most common site.
  • Loss of pain and temperature is common.
  • Weakness of muscles in arms with atrophy and hyporeflexia
  • CST involvement with brisk reflexes in the legs, spasticity, and weakness
  • May occur as a late sequelae to trauma

Anterior Cord Syndrome (Case Study 2)

  • Essentially all ascending and descending tracts are involved except those of the dorsal column.
  • Bilateral loss of discriminative pain and temperature and paralysis below the level of the lesion.
  • Proprioception and discriminative touch remain intact.

Spinal Cord Arteries

  • The anterior spinal artery supplies the anterior two-thirds of the spinal cord.
  • It is formed by the branches of the vertebral arteries.
  • The posterior spinal arteries supply the posterior one-third of the spinal cord.
  • Each vertebral artery produces a single such posterior artery.
  • The artery of Adamkiewicz is the most important radiculomedullary artery.
  • Artery of Adamkiewicz arises from T9 to T12, or T8 to L3.
  • Injury to the artery of Adamkiewicz can lead to paraplegia.

Brown-Séquard Syndrome (Case Study 3)

  • All ascending and descending tracts on one side of the spinal cord are affected.
  • Involvement of the dorsal column causes ipsilateral loss of proprioception and discriminative touch below the lesion.
  • Involvement of the anterolateral spinothalamic tract causes contralateral loss of crude touch, pain, and temperature a few levels below the lesion.
  • The anterolateral spinothalamic tracts ascend ipsilaterally several segments before decussating.
  • Involvement of descending tracts causes ipsilateral paralysis below the level of the lesion.
  • Cord hemisection is caused by a truama or tumor, resulting in dissacoated sensory loss
  • The pathway in brainstem crosses at the level of the brainstem
  • There is Weakness and UMN findings ipsilateral to lesion

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Spinal Cord Injuries PDF

Description

This quiz assesses knowledge of spinal cord lesions and syndromes. Topics covered include lesion localization based on clinical signs, Brown-Sequard syndrome, and characteristic features of spinal cord disease. Also tested is the clinical significance of the spinal cord's termination point.

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