Specimen Quality in Lab Tests
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Questions and Answers

What is hemolysis primarily caused by?

  • High alcohol levels in blood
  • Venipuncture from a small gauge needle
  • Excessive force while pulling the plunger (correct)
  • Inadequate sterilization of the venipuncture site

Which appearance is indicative of icterus in serum or plasma?

  • Yellow coloration (correct)
  • Milky white color
  • Clear and transparent
  • Bright red color

What condition results in serum that appears milky and white?

  • Icterus
  • Lipemia (correct)
  • Dehydration
  • Hemolysis

What is a common procedural error that can lead to lipemia?

<p>Failure to verify fasting requirements (D)</p> Signup and view all the answers

What is the primary consequence of hemolysis during blood testing?

<p>Contamination of serum or plasma with cell contents (B)</p> Signup and view all the answers

Flashcards

Hemolysis

The rupture of red blood cells, contaminating serum or plasma.

Icterus

Serum/plasma with high bilirubin levels, often leading to yellowing of skin and eyes.

Lipemia

High fat/lipid content in blood serum, making it milky white.

Causes of Hemolysis

Errors in venipuncture technique, like using too small a gauge or excessive force when drawing blood.

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Lipemic Serum

Serum with a milky white appearance due to high fat levels, not a venipuncture error, but a patient's diet.

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Study Notes

Specimen Quality: Overview

  • Specimen quality refers to the condition of a blood sample, crucial for accurate lab results.
  • Different conditions of blood samples, such as hemolysis, icterus, and lipemia, affect the quality and reliability of lab tests.

Hemolysis

  • Hemolysis is the rupture or breaking of red blood cell membranes.
  • The contents of the ruptured red blood cells contaminate the serum or plasma, making the specimen unsuitable for analysis.
  • A darker red color indicates more hemolyzed cells.
  • Common causes of hemolysis include:
    • Drawing from a hematoma
    • A small gauge needle
    • Alcohol on the venipuncture site
    • Air leakage and frothing of the blood
    • Pulling the plunger with excessive force
    • Extreme temperature changes

Icterus

  • Icterus indicates a high bilirubin level in the serum or plasma.
  • The patient's skin and sclera (whites of eyes) may appear yellow.
  • Icteric serum or plasma has a yellow color.
  • Icterus is often due to the patient's condition, not phlebotomy error.

Lipemia

  • Lipemia signifies a high amount of fats and lipids in the blood sample.
  • Lipemic serum or plasma appears white or milky.
  • Lipemia is usually due to the patient's condition, like not fasting.
  • Sometimes it can be a procedural error, where a phlebotomist didn't enforce fasting or diet restrictions.

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Description

This quiz covers the importance of specimen quality in laboratory testing, focusing on hemolysis and icterus. Understand how various conditions affect blood sample reliability and what factors contribute to sample degradation. Test your knowledge on maintaining optimal specimen conditions for accurate lab results.

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