SPDBV: Protein Structure Analysis Tools
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Questions and Answers

What type of analysis can be performed using SPDBV's analysis tools?

  • Measurement of distances, calculation of bond angles, and analysis of secondary structure elements (correct)
  • Only tertiary structure analysis
  • Only secondary structure analysis
  • Only primary structure analysis
  • What is the primary purpose of the sequence-structure alignment feature in SPDBV?

  • To perform energy minimization or molecular dynamics simulations
  • To visualize the correspondence between sequence positions and structural elements (correct)
  • To customize display modes for highlighting specific aspects of the structure
  • To identify potential ligand-binding sites or active sites within the structure
  • What is the purpose of energy minimization or molecular dynamics simulations in SPDBV?

  • To optimize the geometry and stability of protein structures (correct)
  • To analyse secondary structure elements
  • To visualize the structure in cartoon representation
  • To identify potential ligand-binding sites or active sites within the structure
  • What can be customized in SPDBV's display modes?

    <p>The display modes to highlight specific aspects of the structure</p> Signup and view all the answers

    What is the purpose of identifying conserved residues in SPDBV?

    <p>To map sequence variations</p> Signup and view all the answers

    What can be modified in SPDBV's molecular editing feature?

    <p>Protein structures, adding or deleting atoms or residues, and generating mutant models</p> Signup and view all the answers

    What type of information does PDBsum provide about experimental methods?

    <p>Summaries of experimental methods used for structure determination</p> Signup and view all the answers

    What is the primary function of PDBsum's functional annotations?

    <p>To provide insights into the biological significance of protein structures</p> Signup and view all the answers

    What type of information does PDBsum provide about ligand binding sites?

    <p>All of the above</p> Signup and view all the answers

    What is the purpose of PDBsum's structural comparisons?

    <p>To analyze similarities and differences between protein structures</p> Signup and view all the answers

    What tools does PDBsum use for structural comparisons?

    <p>Dali Lite and TM-align</p> Signup and view all the answers

    What type of features does PDBsum annotate in biomolecular complexes?

    <p>Biologically relevant features such as active sites, metal binding sites, and post-translational modifications</p> Signup and view all the answers

    What is the primary advantage of the PDB file format?

    <p>It is human-readable and can be edited using text editors</p> Signup and view all the answers

    What type of data may be included in additional sections of PDB files?

    <p>Ligands, solvent molecules, symmetry information, or experimental metadata</p> Signup and view all the answers

    What is the primary goal of Multiple Sequence Alignment?

    <p>To determine the evolutionary relationships among sequences</p> Signup and view all the answers

    Which method of Multiple Sequence Alignment constructs a guide tree based on pairwise sequence similarities?

    <p>ClustalW</p> Signup and view all the answers

    What is the advantage of Clustal Omega over ClustalW?

    <p>It has enhanced accuracy and scalability</p> Signup and view all the answers

    How many biological sequences are typically aligned in Multiple Sequence Alignment?

    <p>Three or more</p> Signup and view all the answers

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