Somatic Recombination and VDJ Recombinase Quiz
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Questions and Answers

Which enzyme is responsible for the somatic recombination of V and J, or of V, D, and J, gene segments?

  • VDJ recombinase (correct)
  • transcription factors
  • RAG-1 and RAG-2 proteins
  • ligases
  • Which cells express the VDJ recombinase?

  • Only T lymphocytes
  • Immature B and T lymphocytes (correct)
  • Only B lymphocytes
  • Mature B and T lymphocytes
  • Which genes are rearranged and expressed only in B cells?

  • RAG-1 and RAG-2 genes
  • VDJ genes
  • Intact Ig heavy-chain and light-chain genes (correct)
  • TCR α and β genes
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