3 Questions
Which enzyme is responsible for the somatic recombination of V and J, or of V, D, and J, gene segments?
VDJ recombinase
Which cells express the VDJ recombinase?
Immature B and T lymphocytes
Which genes are rearranged and expressed only in B cells?
Intact Ig heavy-chain and light-chain genes
Test your knowledge on somatic recombination and the role of VDJ recombinase in DNA repair. Explore the functions of RAG-1 and RAG-2 proteins in this lymphocyte-specific process.
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