Questions and Answers
Which drug class does Solifenacin Succinate (VESIcare) belong to?
What is the brand name of Solifenacin Succinate?
VESIcare
The initial dosage of Solifenacin Succinate is ______ mg/day.
5
Patients should not exceed a maximum dosage of ______ mg/day of Solifenacin Succinate.
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Which of the following is a contraindication for Solifenacin Succinate?
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What are the therapeutic effects of Solifenacin Succinate?
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How does Solifenacin Succinate work?
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Match the following side effects to Solifenacin Succinate:
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Which of the following is considered a life-threatening adverse reaction of Solifenacin Succinate?
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Study Notes
Drug Class
- Solifenacin Succinate is classified as a urinary antimuscarinic and anticholinergic.
- Functions as a bladder antispasmodic, targeting overactive bladder symptoms.
Brand Name
- Marketed under the brand name VESIcare.
Dosage
- Initial dosage is 5 mg orally per day, which can be increased to a maximum of 10 mg daily.
Contraindications/ Cautions
- Contraindicated in patients with glaucoma, gastroparesis, gastrointestinal obstruction, urinary retention, and certain arrhythmias.
- Caution advised for individuals with alcoholism, angioedema, dementia, bradycardia, coronary artery disease, diabetes mellitus, gastroesophageal reflux disease, heart failure, hypertension, breastfeeding, and those who wear contact lenses.
Therapeutic Effects/ Uses
- Indicated for the treatment of overactive bladder and urinary incontinence.
Mechanism of Action
- Acts as a selective muscarinic receptor antagonist, affecting all muscarinic receptors.
- Reduces both voluntary and involuntary bladder contractions, reduces salivary gland secretions, impacts gastric ciliary muscle function, and has effects on the central nervous system.
Side Effects
- Common side effects include blurred vision, dizziness, confusion, cough, pharyngitis, dry mouth, nausea, vomiting, abdominal pain, constipation, urinary retention, and peripheral edema.
Adverse Reactions
- Serious adverse reactions can include palpitations, hypertension, tachycardia, renal impairment, gastrointestinal obstruction, and angioedema.
- Life-threatening conditions may occur such as dysrhythmias, hyperkalemia, and torsades de pointes.
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Description
This quiz provides essential flashcard information about Solifenacin Succinate, also known as VESIcare. Review drug classifications, brand names, dosages, and contraindications to enhance your pharmacology knowledge. Perfect for students preparing for exams in pharmacy or medical studies.
