Sodium Phosphate and Topical Compounds
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Questions and Answers

Which of the following metals is contraindicated in certain poisonings due to higher renal toxicities of their complexes?

  • Zinc
  • Iron (correct)
  • Lead
  • Copper
  • It is safe to use certain treatments in cases of cadmium poisoning.

    False

    Name one metal that should not be treated with certain therapies due to the formation of more toxic complexes.

    Cadmium

    In poisoning cases involving __________, it is contraindicated to use certain treatments due to the increased renal toxicity of the resulting complexes.

    <p>iron</p> Signup and view all the answers

    Match the following metals with their contraindicated treatment consequences:

    <p>Iron = Increased renal toxicity of complexes Cadmium = Greater renal toxicities than free metals Selenium = Toxic complex formation Lead = No contraindications mentioned</p> Signup and view all the answers

    Study Notes

    Sodium Phosphate

    • Contraindications: Sodium Phosphate is contraindicated in poisonings from iron, cadmium, or selenium due to the increased renal toxicity of the resulting complexes compared to the free metals.
    • Absorption: Poorly absorbed from the gastrointestinal tract.
    • Administration: Intravenous administration is typically conducted through slow infusion with isotonic sodium chloride or other electrolyte solutions.
    • Physical Properties: Colorless or white granular salt that effervesces in warm, dry air.
    • Solution Properties: Solutions are alkaline, with a 0.1 M solution exhibiting a pH of approximately 9.5. Freely soluble in water and very slightly soluble in alcohol.

    Topical Compounds

    • Categorization: Classified based on actions:
      • Protective agents
      • Antimicrobial agents
      • Astringent compounds
    • Action: Primarily target small blood vessels (smooth muscle) and are applied topically.
    • Astringent Action: Limited penetration, causing a mild antimicrobial effect and restricting blood flow without causing cell death.

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    Description

    This quiz covers the properties, contraindications, and administration routes of Sodium Phosphate, alongside the categorization and action of topical compounds. Key focus areas include absorption characteristics, physical properties, and specific uses of these compounds in therapy.

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