Podcast
Questions and Answers
What class is Sodium Bicarbonate?
What class is Sodium Bicarbonate?
Systemic Hydrogen Ion Buffer, Alkalizing Agent.
What is Sodium Bicarbonate's mechanism of action?
What is Sodium Bicarbonate's mechanism of action?
Buffers metabolic acidosis and lactic acid buildup by reacting with hydrogen ions to form water and carbon dioxide.
What are the indications for Sodium Bicarbonate?
What are the indications for Sodium Bicarbonate?
Metabolic acidosis during cardiac arrest, overdose on tricyclic antidepressants, aspirin, phenobarbital, hyperkalemia, and crush injuries.
What are the contraindications for Sodium Bicarbonate?
What are the contraindications for Sodium Bicarbonate?
Signup and view all the answers
What are some adverse reactions/side effects of Sodium Bicarbonate?
What are some adverse reactions/side effects of Sodium Bicarbonate?
Signup and view all the answers
What are the drug interactions for Sodium Bicarbonate?
What are the drug interactions for Sodium Bicarbonate?
Signup and view all the answers
How is Sodium Bicarbonate supplied?
How is Sodium Bicarbonate supplied?
Signup and view all the answers
What is the dosage and administration of Sodium Bicarbonate for an adult?
What is the dosage and administration of Sodium Bicarbonate for an adult?
Signup and view all the answers
What is the duration of action for Sodium Bicarbonate?
What is the duration of action for Sodium Bicarbonate?
Signup and view all the answers
What are some special considerations for Sodium Bicarbonate?
What are some special considerations for Sodium Bicarbonate?
Signup and view all the answers
Study Notes
Sodium Bicarbonate Overview
- Class: Systemic Hydrogen Ion Buffer and Alkalizing Agent.
Mechanism of Action
- Buffers metabolic acidosis and lactic acid buildup by reacting with hydrogen ions to produce water and carbon dioxide.
- Effective in counteracting anaerobic metabolism secondary to severe hypoxia.
Indications for Use
- Administer during metabolic acidosis associated with cardiac arrest.
- Used in cases of tricyclic antidepressant, aspirin, and phenobarbital overdoses.
- Treatment for hyperkalemia and crush injuries.
Contraindications
- Avoid use in metabolic or respiratory alkalosis.
- Do not use in patients with hypokalemia or electrolyte imbalances due to severe vomiting or diarrhea.
Adverse Reactions and Side Effects
- Possible seizures, fluid retention, and hypokalemia.
- Risk of electrolyte imbalances, tetany, sodium retention, peripheral edema, and hypernatremia.
- May lead to metabolic alkalosis and tissue complications such as sloughing, cellulitis, or necrosis at the injection site.
Drug Interactions
- Increases the effects of amphetamines.
- Decreases the effectiveness of benzodiazepines and tricyclic antidepressants.
- May deactivate sympathomimetics like dopamine, epinephrine, and norepinephrine.
Supply Forms
- Supplied as 1 mEq/mL in an 8.4% solution available in 10- and 50-mL vials or prefilled syringes.
- Also available as 0.5 mEq/mL in a 4.2% solution in 2.5-, 5-, and 10-mL prefilled syringes.
Dosage and Administration
- Administer 1 mEq/kg via slow IV or IO push; may repeat at 0.5 mEq/kg every 10 minutes as needed.
Duration of Action
- Onset of action is within seconds; peak effect occurs in 1 to 2 minutes.
- Duration of action lasts approximately 10 minutes.
Special Considerations
- Pregnancy safety category: C.
- In tricyclic antidepressant overdose, repeat dosing until QRS narrows.
- Must be used alongside effective ventilation and chest compressions in cardiac arrest scenarios.
- Avoid mixing with other medications to prevent precipitation or inactivation.
- Important to flush the IV line thoroughly before and after administration.
- Use caution in patients with congestive heart failure (CHF) and renal disease due to high sodium concentration.
- Monitor closely for signs of fluid overload.
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Description
Test your knowledge of Sodium Bicarbonate with this quiz designed for paramedic students. Learn about its classification, mechanism of action, and therapeutic uses in managing metabolic acidosis. Perfect for quick revision before exams!