Dermatology

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Questions and Answers

Which of the following is NOT a characteristic of oral mucosa compared to cutaneous epithelium?

  • Increased mechanical trauma
  • Increased membrane permeability (correct)
  • Decreased inflammation
  • Increased cell proliferation (correct)

What term describes a single area of altered skin?

  • Rash
  • Plaque
  • Dermatosis
  • Lesion (correct)

Which of the following best characterizes a 'plaque' in dermatological terms?

  • Elevated and solid lesion less than 1cm.
  • Small, flat alteration in skin color.
  • Circumscribed, elevated lesion greater than 1cm. (correct)
  • Fluid-filled blister less than 1cm.

What is 'crusting' composed of in the context of skin conditions?

<p>Dried exudate (plasma, keratin, and cells) (B)</p> Signup and view all the answers

Which of the following is LEAST likely to be part of a general management strategy for skin disorders?

<p>Allergy tests (B)</p> Signup and view all the answers

Which symptom is least associated with rashes?

<p>Hair Loss (A)</p> Signup and view all the answers

Which of the following conditions is NOT typically classified as an inflammatory skin condition?

<p>Shingles (A)</p> Signup and view all the answers

What is a common trigger for seborrheic dermatitis?

<p>Cold/Dry weather (B)</p> Signup and view all the answers

A patient presents with erythematous lesions covered by a 'cornflake crust.' Which condition is most likely?

<p>Impetigo (B)</p> Signup and view all the answers

Which of the following is a key characteristic of shingles?

<p>Rash restricted to one side of the body (B)</p> Signup and view all the answers

Which of the following is a symptom of measles?

<p>Koplik's spots (D)</p> Signup and view all the answers

What is a key feature of folliculitis?

<p>Bumps/pimples around hair follicles (D)</p> Signup and view all the answers

Which of the following is a characteristic of acne?

<p>Blackheads and whiteheads (D)</p> Signup and view all the answers

Which of the following is a common symptom of rosacea?

<p>Redness (B)</p> Signup and view all the answers

Which of the following factors is least likely to be associated with perioral dermatitis?

<p>Sun exposure (B)</p> Signup and view all the answers

Which of the following is NOT one of the '6 Ps' associated with Lichen Planus?

<p>Pustular (B)</p> Signup and view all the answers

What is a typical characteristic observed in nail psoriasis?

<p>Nail pitting and separation (C)</p> Signup and view all the answers

Which of the following is a characteristic feature of acute cutaneous lupus erythematosus?

<p>Butterfly rash (C)</p> Signup and view all the answers

Erythema Multiforme (EM) is what type of hypersensitivity reaction?

<p>Type 4 (B)</p> Signup and view all the answers

Which of these options is considered a cause of erythema multiforme (EM)?

<p>Herpes simplex virus (C)</p> Signup and view all the answers

What are the defining characteristics of TRUE typical Erythema Multiforme (EM) lesions?

<p>&lt;3cm, round, symmetric, well-defined, 3 concentric zones (D)</p> Signup and view all the answers

Which of the following should be considered if a patient's symptoms are more severe/they are unwell, after a diagnosis of Erythema Multiforme?

<p>Stevens-Johnson syndrome (SJS) (C)</p> Signup and view all the answers

When describing morphology - which of these options is defined as a 'full loss of epidermis and portion of the dermis +/- subcutaneous tissue?'

<p>Ulcer (B)</p> Signup and view all the answers

True or false: Target lesions are pathognomonic for EM (erythema multiforme)?

<p>False (A)</p> Signup and view all the answers

What is the 'primary' difference between EM Minor and EM Major?

<p>EM Minor has no mucosal involvement, EM Major involves one or more mucosa. (D)</p> Signup and view all the answers

Which of the following features is typically associated with cutaneous epithelium but not oral mucosa?

<p>Hair follicles (D)</p> Signup and view all the answers

What term best describes a widespread eruption of similar skin lesions?

<p>Rash (D)</p> Signup and view all the answers

Which characteristic is most indicative of a 'nodule' when describing skin lesion morphology?

<p>Elevated and solid, more than 1cm (A)</p> Signup and view all the answers

In the context of skin lesion morphology, what is the defining characteristic of an 'erosion'?

<p>Superficial or partial destruction of the epidermis (D)</p> Signup and view all the answers

Which of the following is least likely to be considered as a first-line treatment in the general management of most skin disorders?

<p>Surgery (D)</p> Signup and view all the answers

Which of the following symptoms is least likely to be a primary characteristic of rashes in general?

<p>Alopecia (C)</p> Signup and view all the answers

Which of the following conditions is least likely to be initially suspected as an inflammatory skin condition?

<p>Impetigo (C)</p> Signup and view all the answers

Which of the following environmental factors is least associated with triggering seborrheic dermatitis?

<p>High Humidity (B)</p> Signup and view all the answers

Which of the following microorganisms is primarily associated with impetigo?

<p>Staph aureus (C)</p> Signup and view all the answers

In the context of shingles, what does 'rash restricted to one side' refer to?

<p>Unilateral dermatomal distribution (C)</p> Signup and view all the answers

What specific symptom is associated with measles due to the infection?

<p>Koplik's Spots (B)</p> Signup and view all the answers

What anatomical structure is primarily affected in cases of folliculitis?

<p>Hair follicles (B)</p> Signup and view all the answers

Which of the following is a symptom associated with acne?

<p>Blackheads (C)</p> Signup and view all the answers

Which trigger is least associated with Rosacea?

<p>Cold drinks (A)</p> Signup and view all the answers

Fluorinated toothpaste is associated with which of these skin conditions?

<p>Perioral dermatitis (D)</p> Signup and view all the answers

Which of the following is among the '6 Ps' used to describe Lichen Planus?

<p>Planar (D)</p> Signup and view all the answers

Which specific finding is commonly observed in nail psoriasis?

<p>Nail pitting (A)</p> Signup and view all the answers

Which of the following is a characteristic feature of acute cutaneous lupus erythematosus ('acute skin lupus')?

<p>Butterfly rash (D)</p> Signup and view all the answers

What type of hypersensitivity reaction is Erythema Multiforme?

<p>Type 4 (D)</p> Signup and view all the answers

What is the most common cause of Erythema Multiforme (EM)?

<p>Herpes simplex virus (HSV) (A)</p> Signup and view all the answers

What key morphologic feature defines typical Erythema Multiforme (EM) lesions?

<p>Well-defined, three concentric zones (C)</p> Signup and view all the answers

In the context of Erythema Multiforme, what condition should be considered if a patient presents with severe symptoms or is unwell?

<p>Stevens-Johnson Syndrome (SJS) (A)</p> Signup and view all the answers

Which term accurately describes the skin morphology characterized by a 'full loss of epidermis and portion of the dermis +/- subcutaneous tissue'?

<p>Ulcer (D)</p> Signup and view all the answers

In distinguishing between EM Minor and EM Major, what is the primary differentiating factor?

<p>Mucosal involvement (A)</p> Signup and view all the answers

A patient presents with small, erythematous bumps around hair follicles, some of which contain pus. Pruritis and mild pain are reported. What is the most likely diagnosis?

<p>Folliculitis (B)</p> Signup and view all the answers

Which of the following is a key characteristic of cutaneous epithelium compared to oral mucosa?

<p>Increased membrane permeability (A)</p> Signup and view all the answers

What is the primary function associated with the reticular layer of the dermis?

<p>Providing a scaffolding for blood vessels and nerves (B)</p> Signup and view all the answers

Which structure is responsible for sebum production?

<p>Sebaceous gland (D)</p> Signup and view all the answers

In the context of skin morphology, what differentiates a bulla from a vesicle?

<p>Size; a bulla is larger than 1cm while a vesicle is smaller than 1cm (D)</p> Signup and view all the answers

Which of the following best describes an 'erosion' in dermatology?

<p>Superficial or partial destruction of the epidermis (C)</p> Signup and view all the answers

Which of the following is the most appropriate initial treatment for mild inflammatory skin conditions?

<p>Emulsifying ointments and oatmeal baths (B)</p> Signup and view all the answers

A patient presents with a localized collection of pus. Which term accurately describes this skin condition?

<p>Abscess (A)</p> Signup and view all the answers

Which of the following symptoms is most indicative of contact dermatitis?

<p>Erythema and pruritus (C)</p> Signup and view all the answers

What is the most characteristic feature of rashes caused by insect bites?

<p>Localized swelling and erythema (D)</p> Signup and view all the answers

Which of the following is a common trigger for seborrheic dermatitis?

<p>Fungal infection by Malassezia (A)</p> Signup and view all the answers

Shingles is caused by the reactivation of which virus?

<p>Varicella-Zoster virus (C)</p> Signup and view all the answers

Which of the following is a characteristic symptom of measles?

<p>Red, blotchy rash starting on the forehead (B)</p> Signup and view all the answers

Folliculitis is best described as:

<p>Inflammation of the hair follicles (D)</p> Signup and view all the answers

Which of the following is a common characteristic of acne?

<p>Blackheads, whiteheads, and pustules (A)</p> Signup and view all the answers

Rosacea is often triggered by:

<p>Spicy foods and alcohol (D)</p> Signup and view all the answers

Which of the following factors is most likely associated with perioral dermatitis?

<p>Topical steroid use (D)</p> Signup and view all the answers

Which of the following is a common feature of Lichen Planus?

<p>Purple, pruritic, polygonal papules (C)</p> Signup and view all the answers

Which of these nail changes is most commonly associated with psoriasis?

<p>Nail pitting (A)</p> Signup and view all the answers

What is the characteristic 'butterfly rash' associated with?

<p>Acute cutaneous lupus erythematosus (A)</p> Signup and view all the answers

Erythema Multiforme (EM) is primarily mediated by which type of hypersensitivity reaction?

<p>Type IV (B)</p> Signup and view all the answers

Which of the following is the most common cause of Erythema Multiforme (EM)?

<p>Herpes simplex virus infection (C)</p> Signup and view all the answers

What is the hallmark morphological characteristic of a TRUE typical Erythema Multiforme (EM) lesion?

<p>Well-defined, round, symmetrical target lesions with three concentric zones (A)</p> Signup and view all the answers

In the context of skin disorders, what is the key distinguishing feature of a 'fissure'?

<p>A linear or narrow erosion or ulcer (D)</p> Signup and view all the answers

If a patient is diagnosed with Erythema Multiforme and begins to show signs of systemic illness, what potential condition should be considered?

<p>Stevens-Johnson syndrome (SJS) or Toxic Epidermal Necrolysis (TEN) (D)</p> Signup and view all the answers

Why is it crucial to distinguish Erythema Multiforme (EM) from Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN)?

<p>SJS/TEN necessitates immediate, specialized care due to its potential severity, whereas EM is often self-limiting (A)</p> Signup and view all the answers

Which of the following is a typical autoantibody target in Pemphigus vulgaris?

<p>Desmoglein 3 (D)</p> Signup and view all the answers

What is the typical blister location in Bullous Pemphigoid?

<p>Subepidermal (deep) (C)</p> Signup and view all the answers

What type of antibodies are typically elevated in patients with Dermatitis Herpetiformis?

<p>IgA (A)</p> Signup and view all the answers

In Dermatitis Herpetiformis, where are granular IgA deposits typically found upon direct immunofluorescence?

<p>At the dermal papillae (A)</p> Signup and view all the answers

A patient with Dermatitis Herpetiformis is likely to be advised to avoid which dietary component?

<p>Gluten (B)</p> Signup and view all the answers

Which of the following is NOT typically associated with Atopic Dermatitis?

<p>Increased ceramide production (A)</p> Signup and view all the answers

Which component is a part of the atopic triad?

<p>Hay fever (A)</p> Signup and view all the answers

Which of the following is NOT a typical cause of acute urticaria?

<p>Chronic stress (C)</p> Signup and view all the answers

What is a characteristic symptom of urticaria?

<p>Raised welts with clearly defined borders (A)</p> Signup and view all the answers

Which type of miliaria is characterized by clear, non-itchy vesicles close to the skin surface?

<p>Miliaria crystallina (A)</p> Signup and view all the answers

Which form of heat rash involves flesh-colored, tender papules deep in the skin?

<p>Miliaria profunda (D)</p> Signup and view all the answers

Following multiple episodes of heat rash, which type of miliaria is most likely to develop in adults?

<p>Miliaria profunda (D)</p> Signup and view all the answers

Which of the following is considered a benign tumour of the skin?

<p>Seborrheic keratosis (C)</p> Signup and view all the answers

Which of the following factors is most closely associated with the development of skin tags (acrochordons)?

<p>Acrochordons (D)</p> Signup and view all the answers

What is a common characteristic of cherry angiomas?

<p>They are round and uniform in shape (D)</p> Signup and view all the answers

Which of the following pigmented lesions is directly related to sun exposure?

<p>Ephelis (D)</p> Signup and view all the answers

Which factor is most strongly associated with the development of lentigo solar?

<p>UV radiation (C)</p> Signup and view all the answers

Which of the listed options is NOT a risk factor associated with skin cancer?

<p>Increased melanin production (A)</p> Signup and view all the answers

A patient presents with a skin lesion exhibiting asymmetry, irregular borders, and varied colors. Which skin condition is most concerning and requires further evaluation?

<p>Malignant melanoma (B)</p> Signup and view all the answers

New skin lesions, itching of a lesion and easy bleeding are the most common warning signs of which type of skin cancer?

<p>Basal cell carcinoma (B)</p> Signup and view all the answers

Which of the following is a typical presentation of basal cell carcinoma (BCC)?

<p>Pink or translucent, pearly bumps (D)</p> Signup and view all the answers

Which form of skin cancer arises from malignant transformation of squamous cells?

<p>Squamous cell carcinoma (B)</p> Signup and view all the answers

What is a diagnostic feature often observed in biopsies of squamous cell carcinoma (SCC)?

<p>Keratin pearls (B)</p> Signup and view all the answers

A 68-year-old male presents with a firm, painless, red nodule on his scalp that bleeds easily. Which of the following is the most likely diagnosis?

<p>Squamous cell carcinoma (A)</p> Signup and view all the answers

In the treatment of squamous cell carcinoma (SCC), which of the following factors would most strongly indicate the need to remove affected lymph nodes?

<p>Evidence of metastasis (C)</p> Signup and view all the answers

In distinguishing between bullous pemphigoid and pemphigus vulgaris, which of the following is a characteristic feature of bullous pemphigoid?

<p>Subepidermal (deep) blister location (B)</p> Signup and view all the answers

Which of the following autoantibodies is associated with Pemphigus vulgaris?

<p>Against desmoglein 3 (A)</p> Signup and view all the answers

In the context of Dermatitis Herpetiformis, what is the significance of screening for Celiac disease?

<p>To manage the underlying cause of Dermatitis Herpetiformis. (D)</p> Signup and view all the answers

What is the primary dietary recommendation for managing Dermatitis Herpetiformis?

<p>A gluten-free diet (A)</p> Signup and view all the answers

Which of the following blood test results would be most indicative of Dermatitis Herpetiformis?

<p>Elevated IgA tissue transglutaminase antibodies (A)</p> Signup and view all the answers

A skin biopsy of a patient with suspected Dermatitis Herpetiformis is performed. What finding on direct immunofluorescence would be considered pathognomonic for this condition?

<p>Granular deposits of IgA at the dermal papillae (C)</p> Signup and view all the answers

A patient is diagnosed with Dermatitis Herpetiformis. What other condition should they be screened for?

<p>Celiac disease (C)</p> Signup and view all the answers

Which area of the body is least likely to be affected by pruritic vesicles and papules in Dermatitis Herpetiformis?

<p>Palms (A)</p> Signup and view all the answers

Which of the following factors is least likely to exacerbate atopic dermatitis?

<p>Application of emollients. (A)</p> Signup and view all the answers

Elevated levels of which substance, produced by the nervous system, is associated with Atopic Dermatitis?

<p>Nerve growth factor (B)</p> Signup and view all the answers

What is a typical characteristic symptom of acute urticaria?

<p>Raised welts with clearly defined borders (C)</p> Signup and view all the answers

Which trigger is least associated with acute urticaria?

<p>Bacterial skin infection (D)</p> Signup and view all the answers

In the assessment of urticaria, what key physical finding is typically observed in the welts?

<p>The rash turns white (blanches) when pressed (D)</p> Signup and view all the answers

What is the primary characteristic of Miliaria Crystallina?

<p>Non-itchy, clear vesicles (C)</p> Signup and view all the answers

Which type of miliaria is commonly referred to as 'prickly heat'?

<p>Miliaria Rubra (C)</p> Signup and view all the answers

Which of the following is the least common form of heat rash?

<p>Miliaria Profunda (C)</p> Signup and view all the answers

Which of the following lesions is more likely to develop in adults after multiple episodes of heat rash?

<p>Miliaria profunda (A)</p> Signup and view all the answers

Which of the following skin conditions is classified as a benign tumor?

<p>Seborrheic keratosis (C)</p> Signup and view all the answers

Which factor is most closely associated with the development of acrochordons?

<p>Genetics (C)</p> Signup and view all the answers

Which of the following is a typical characteristic of cherry angiomas?

<p>Round and Uniform (C)</p> Signup and view all the answers

Which of the following pigmented lesions is directly related to chronic sun exposure?

<p>Ephelis (C)</p> Signup and view all the answers

Development of Lentigo solar is associated with:

<p>UV radiation (A)</p> Signup and view all the answers

Which characteristic describes Melanocytic naevi?

<p>They involve proliferation of melanocytes (C)</p> Signup and view all the answers

What feature regarding the development of pigmented lesions is most concerning?

<p>New lesions developing later in life (C)</p> Signup and view all the answers

Which of the following best describes the functionality of cutaneous epithelium regarding membrane permeability, compared to oral mucosa?

<p>Cutaneous epithelium exhibits increased membrane permeability. (A)</p> Signup and view all the answers

Which of the following is the most accurate description of a 'patch' in dermatology?

<p>A large, smooth alteration in color. (B)</p> Signup and view all the answers

Which of the following features is most indicative of a 'cyst'?

<p>A papule or nodule filled with fluid. (B)</p> Signup and view all the answers

What is the composition of 'crusting' in the context of skin conditions?

<p>Dried exudate (plasma, blood, keratin combo). (A)</p> Signup and view all the answers

Which of the following is typically included in a general management strategy for skin disorders?

<p>Oatmeal baths. (A)</p> Signup and view all the answers

Which of the following is a common characteristic of rashes, irrespective of the underlying cause?

<p>Blistering. (B)</p> Signup and view all the answers

Which of the following is least likely to be initially classified as an inflammatory skin condition?

<p>Cherry angioma. (D)</p> Signup and view all the answers

Which of the following is associated with triggering seborrheic dermatitis?

<p>Malassezia yeast. (A)</p> Signup and view all the answers

A patient presents with skin lesions displaying a 'cornflake crust'. Which condition is most likely?

<p>Impetigo. (D)</p> Signup and view all the answers

Which of the following is a definitive characteristic of shingles?

<p>Rash restricted to one side. (A)</p> Signup and view all the answers

What is a typical symptom associated with measles?

<p>Koplik's spots. (C)</p> Signup and view all the answers

What is a common feature of folliculitis?

<p>Bumps/pimples around hair follicles. (A)</p> Signup and view all the answers

Which of the following is a symptom commonly associated with acne?

<p>Spots. (C)</p> Signup and view all the answers

What is a possible trigger for rosacea?

<p>Cold/dry weather. (D)</p> Signup and view all the answers

Which of the following is linked to perioral dermatitis?

<p>Fluorinated toothpaste. (D)</p> Signup and view all the answers

Which of the following is one of the '6 Ps' related to Lichen Planus?

<p>Pruritic. (B)</p> Signup and view all the answers

Which of these findings is often observed in nail psoriasis?

<p>Nail pitting. (D)</p> Signup and view all the answers

What is a characteristic feature of acute cutaneous lupus erythematosus?

<p>Butterfly rash. (D)</p> Signup and view all the answers

Regarding Erythema Multiforme, what condition should be considered if a patient presents with severe symptoms or is unwell?

<p>Stevens-Johnson syndrome (SJS). (C)</p> Signup and view all the answers

Which of the following best describes the appearance of Miliaria Crystallina?

<p>Clear vesicles. (C)</p> Signup and view all the answers

What factor is least likely to be associated with the development of skin tags (acrochordons)?

<p>Chronic sun exposure. (C)</p> Signup and view all the answers

Which characteristic is associated with cherry angiomas?

<p>Round shape, red color, and small size. (D)</p> Signup and view all the answers

Ephelis, a common skin condition, is MOST related to which factor?

<p>Chronic sun exposure. (A)</p> Signup and view all the answers

Concerning lentigo solar, which factor is most strongly associated with its development?

<p>Chronic sun exposure. (D)</p> Signup and view all the answers

Which risk factor is not typically linked to skin cancer development?

<p>High dietary fiber intake. (D)</p> Signup and view all the answers

A patient shows a skin lesion with asymmetry, irregular borders, and varied colors. Which attribute is most concerning and requires further evaluation?

<p>Malignant melanoma. (A)</p> Signup and view all the answers

A patient presents with a new skin lesion reported to itch intermittently and bleeds easily when touched. Which type of skin cancer does this description most effectively support?

<p>Basal cell carcinoma. (B)</p> Signup and view all the answers

Among the following, what skin biopsy features would be most suggestive of squamous cell carcinoma (SCC)?

<p>Keratin pearls. (D)</p> Signup and view all the answers

A 68-year-old male presents with a firm, painless, red nodule on his scalp that bleeds easily. What treatment is almost always indicated?

<p>Excision. (D)</p> Signup and view all the answers

In considering various risk factors for skin cancer, which factor most directly elevates the risk of basal cell nevus syndrome?

<p>Genetic inheritance. (C)</p> Signup and view all the answers

A patient presents with a rash characterized by raised welts that turn white when pressed. Which condition is most likely?

<p>Urticaria. (C)</p> Signup and view all the answers

A patient diagnosed with basal cell carcinoma is undergoing treatment. Which of the following features would be most relevant in determining whether to remove affected lymph nodes?

<p>Evidence of metastasis. (C)</p> Signup and view all the answers

When is the screening for Celiac disease important in the context of Dermatitis Herpetiformis?

<p>To identify a potential trigger and guide dietary management. (D)</p> Signup and view all the answers

What is the primary dietary intervention recommended for individuals diagnosed with Dermatitis Herpetiformis?

<p>Adopting a gluten-free diet. (B)</p> Signup and view all the answers

Where are the itchy vesicles and papules of Dermatitis Herpetiformis least likely to occur?

<p>Palms. (D)</p> Signup and view all the answers

In assessing urticaria, what is a key physical finding typically observed in the welts?

<p>They turn white if pressed. (D)</p> Signup and view all the answers

Which is the least common form of heat rash?

<p>Miliaria profunda (D)</p> Signup and view all the answers

Which of the provided options is the best descriptor for melanocytic naevi?

<p>Moles. (B)</p> Signup and view all the answers

Which feature concerning the development of pigmented lesions is most concerning?

<p>Rapid change. (A)</p> Signup and view all the answers

Which of the following best describes the appearance of a 'macule'?

<p>Small, flat alteration in color. (D)</p> Signup and view all the answers

A patient has a skin condition described as a 'linear narrow erosion'. Which term is BEST used to define this lesion?

<p>Fissure (D)</p> Signup and view all the answers

Which of the following is least associated with the causes of contact dermatitis?

<p>Cold/dry Weather. (B)</p> Signup and view all the answers

The appearance of 'Koplik spots' inside the mouth is characteristic of which childhood illness?

<p>Measles (C)</p> Signup and view all the answers

What is the underlying cause of folliculitis?

<p>Fungal or bacterial infection of hair follicles. (A)</p> Signup and view all the answers

Which of the following is least likely to trigger rosacea symptoms?

<p>Fluorinated toothpaste. (A)</p> Signup and view all the answers

Which of the following features is most indicative of Lichen Planus?

<p>White, lacy appearance (Wickham striae). (B)</p> Signup and view all the answers

In the context of Erythema Multiforme (EM), which characteristic is most important to consider when differentiating it from Stevens-Johnson Syndrome (SJS) or Toxic Epidermal Necrolysis (TEN)?

<p>Involvement of mucous membranes. (C)</p> Signup and view all the answers

A patient presents with skin lesions characterized by granular IgA deposits at the dermal papillae. Which condition is indicated?

<p>Dermatitis Herpetiformis. (B)</p> Signup and view all the answers

Which of the following is a key characteristic of cutaneous epithelium compared to oral mucosa regarding membrane permeability?

<p>Cutaneous epithelium has higher membrane permeability. (A)</p> Signup and view all the answers

Which layer of the skin is responsible for mechanical support and elasticity due to its collagen and elastic fiber content?

<p>Reticular dermis (D)</p> Signup and view all the answers

What primary substance is produced by sebaceous glands?

<p>Sebum (B)</p> Signup and view all the answers

Which of the following accurately defines a 'macule'?

<p>Small, flat alteration in color (A)</p> Signup and view all the answers

What key feature distinguishes a 'papule' from other skin lesions?

<p>Elevated and solid, less than 1cm in diameter (B)</p> Signup and view all the answers

What is the hallmark characteristic of a 'pustule'?

<p>Circumscribed and filled with pus (C)</p> Signup and view all the answers

Which of the following is the most accurate description of a skin 'ulcer'?

<p>Full loss of epidermis and portion of the dermis +/- subcutaneous tissue (C)</p> Signup and view all the answers

Which of the following is classified as a blood test?

<p>Allergy tests (D)</p> Signup and view all the answers

What is the primary purpose of using emulsifying ointments?

<p>To moisturize and protect the skin (C)</p> Signup and view all the answers

In the general management of skin disorders, what is the role of antihistamines?

<p>To relieve itching (C)</p> Signup and view all the answers

Which of the following is the primary symptom associated with contact dermatitis?

<p>Pruritus (B)</p> Signup and view all the answers

What feature is typically associated with rashes caused by insect bites?

<p>Swelling (lump) (A)</p> Signup and view all the answers

What clinical feature is most commonly observed in cases of impetigo?

<p>Cornflake crust (D)</p> Signup and view all the answers

Shingles is characterized by which specific feature?

<p>Rash restricted to one side (C)</p> Signup and view all the answers

What is a characteristic symptom of measles?

<p>Koplik's spots inside the mouth (C)</p> Signup and view all the answers

Which symptom below is commonly reported by patients with folliculitis?

<p>Bumps/pimples around hair follicles (B)</p> Signup and view all the answers

Which of the following is the primary characteristic of acne?

<p>Spots (C)</p> Signup and view all the answers

Which of the following is a common trigger for rosacea?

<p>Alcohol (D)</p> Signup and view all the answers

Which is associated with perioral dermatitis?

<p>Topical steroid creams (C)</p> Signup and view all the answers

Regarding the signs and symptoms of Lichen Planus, what is the appearance of Wickham striae?

<p>White, lacy appearance (A)</p> Signup and view all the answers

Which specific feature is commonly observed in nail psoriasis?

<p>Nail pitting (D)</p> Signup and view all the answers

A patient presents with widespread raised welts on their skin that are intensely itchy. When pressed, the welts turn white. What condition is most likely?

<p>Urticaria (D)</p> Signup and view all the answers

How are the vesicles and papules of Dermatitis Herpetiformis typically distributed?

<p>Symmetrically and bilaterally (D)</p> Signup and view all the answers

What is a key physical finding typically observed in urticarial welts?

<p>Blanching/turning white when pressed (C)</p> Signup and view all the answers

Which form of heat rash is characterized by clear, non-itchy vesicles that appear very close to the skin's surface?

<p>Miliaria crystallina (A)</p> Signup and view all the answers

Which lesions are most likely to develop in an adult following repeated episodes of heat rash?

<p>Miliaria profunda (C)</p> Signup and view all the answers

Acrochordons are associated with which of these conditions or factors?

<p>Friction (A)</p> Signup and view all the answers

Which characteristic is consistently associated with cherry angiomas?

<p>Round and uniform shape (D)</p> Signup and view all the answers

Which factor is most associated with the development of lentigo solar?

<p>Chronic sun exposure (B)</p> Signup and view all the answers

What features describe Melanocytic naevi?

<p>Can be congenital or acquired (A)</p> Signup and view all the answers

What is the primary cause of skin changes in systemic lupus erythematosus (SLE)?

<p>Deposition of immune complexes and inflammation (D)</p> Signup and view all the answers

What specific finding on direct immunofluorescence is considered pathognomonic for Dermatitis Herpetiformis?

<p>Granular IgA deposits at dermal papillae (D)</p> Signup and view all the answers

Which of the following skin conditions is often associated with 'prickly heat'?

<p>Miliaria rubra (D)</p> Signup and view all the answers

What is the key characteristic that differentiates a vesicle from a bulla?

<p>Size (B)</p> Signup and view all the answers

A patient presents with small, raised, flesh-colored bumps deep within the skin that are tender to the touch, after spending an extended period in a hot, humid environment. Which condition is most likely?

<p>Miliaria profunda (C)</p> Signup and view all the answers

Which of the following factors is most closely associated with an increased risk of skin tag (acrochordon) development?

<p>Obesity and friction (D)</p> Signup and view all the answers

Which of the following is the most concerning feature of a melanocytic nevus that would indicate a higher risk of malignancy?

<p>Rapid change in size, shape, or color (B)</p> Signup and view all the answers

Which factor below is least associated with triggering rosacea symptoms?

<p>Exposure to humid environments (B)</p> Signup and view all the answers

Hyperpigmentation, also known as melasma, observed on sun-exposed skin is primarily due to increased:

<p>Melanin deposition (C)</p> Signup and view all the answers

Which of the following is a diagnostic feature often observed in biopsies of squamous cell carcinoma (SCC)?

<p>Keratin pearls (B)</p> Signup and view all the answers

A 70-year-old patient presents with a history of sun exposure. Examination reveals a small, nodular lesion with a rolled border and telangiectasias on the nose. What is the most likely diagnosis?

<p>Basal cell carcinoma (C)</p> Signup and view all the answers

Which of the following statements is MOST accurate regarding the general difference between cutaneous epithelium and oral mucosa?

<p>Cutaneous epithelium has decreased membrane permeability. (A)</p> Signup and view all the answers

Flashcards

Epidermis

The outer layer of the skin, providing a protective barrier.

Dermis

Provides the skin's structural support, containing blood vessels, nerve endings, and glands.

Lesion

A lesion is a single area of altered skin, differing in appearance from the surrounding skin.

Rash

A widespread eruption of multiple lesions on the skin.

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Dermatosis

A broad term for any disease affecting the skin.

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Erosion

Superficial or partial destruction of the epidermis.

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Fissure

Linear or narrow erosion or ulcer, often painful.

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Ulcer

Full loss of the epidermis and part of the dermis, potentially exposing subcutaneous tissue.

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Atrophy

Reduction in epidermal and/or dermal thickness.

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Crusting

Dried exudate (plasma, blood, or pus) on the skin surface.

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Macule

Small, flat alteration in skin color.

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Patch

A large macule with a smooth surface.

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Papule

Elevated, solid lesion less than 1 cm in diameter.

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Nodule

Solid, elevated lesion greater than 1 cm in diameter.

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Cyst

Papule or nodule filled with fluid.

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Plaque

Circumscribed, elevated lesion greater than 1 cm.

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Vesicle

Small blister less than 1 cm in diameter.

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Bulla

Large blister greater than 1 cm in diameter.

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Abscess

Circumscribed collection of pus.

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Pustule

A circumscribed lesion containing pus.

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Rashes

Changes in color, texture, or feel of the skin surface.

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Erythema Multiforme (EM)

Skin lesions are usually acute, acrally distributed and can be typical, atypical or a combination of both.

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EM Minor

No mucosa involved

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EM Major

Involves one or more mucosa (e.g. eyes, GU, GI tract)

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Cutaneous Epithelium

Outer layer of oral mucosa with permeability pathways.

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Oral Mucosa

Epithelium layer that includes saliva, peptides, peroxidase, growth factors and provides the mouth with a lining.

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Rashes Causes

Changes in color, texture, or feel of the skin surface.

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Rashes Symptoms

Includes blistering, redness, dry skin, itchiness and pain.

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Typical EM lesions

Typical (<3cm, round, symmetric, well-defined, 3 concentric zones)

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Insect bites

Includes Mosquitos, Ticks, Lice, Fleas, Spiders, Bees, Wasps & Hornets.

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Acne

Secondary bacterial infection

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Rosacea

A common inflammatory skin condition with redness, swelling, spots, and blood vessels.

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Lichen Planus - 6 P's

Pruritic, planar, polygonal, purple, plaques, papules.

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Psoriasis

Inflamed skin and scaly, silvery plaques with a clear border.

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Systemic Lupus Erythematosus

Autoimmune disease affecting the skin, joints, heart, lungs, and kidneys.

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Contact dermatitis Rash

Contact dermatitis

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Seborrheic dermatitis

Common trigger - cold/dry weather

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Shingles - infection

Rash restricted to one side.

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Folliculitis

Bump and pimples around the hair follicles.

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Dermoscopy

Dermoscopy uses a special magnifying device to examine skin lesions in detail, aiding in diagnosis.

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Topical/Systemic Steroids

Topical application or oral administration of drugs reduces inflammation in the skin.

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Immunosuppressants

Medications used to suppress the immune system's response to skin conditions.

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Immunomodulators

Medications that modulate or adjust the immune system's activity.

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Surgery for skin disorders

Excision or repair of skin lesions via surgical means.

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Allergy test

Skin allergy test involving exposure to substances to identify triggers.

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Swabs and Smears

Test to identify and detect bacteria, fungi or viruses.

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Biopsy

Tissue sample examination for diagnosis.

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Imaging

Diagnostic technique reveals details beneath surface

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Chemical-induced rashes

Rashes caused by chemicals like latex, soaps, or dyes.

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Natural Ingredient Rashes

Rashes resulting from exposure to poison ivy or insect bites.

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Malassezia or seborrheic Dermatitis

A harmless yeast causes scaly, itchy skin; triggers like fatigue and stress.

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Connective tissue disorders

Skin diseases from connective tissue and its disorders, may also form bullous

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Impetigo

Infection with Staph aureus. Occurs In children. Non-bullous/Bullous.

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Bullous Pemphigoid

Immunological mediated disease with blisters and characterized by tense and firm blisters deep in the skin.

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Pemphigus Vulgaris

Autoimmune disease with flaccid blisters that easily rupture.

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Dermatitis Herpetiformis

Itchy, vesicular skin manifestation of celiac disease, often found on elbows and knees.

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Atopic Dermatitis (Eczema)

Chronic, itchy inflammatory disease.

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Urticaria (Hives)

Raised welts with defined borders appearing anywhere on the body.

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Miliaria (Heat Rash)

Skin reaction due to blocked sweat ducts.

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Miliaria Rubra

Type of heat rash where there are red bumps.

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Seborrheic Keratosis

The common benign skin neoplasm, seen more with age.

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Skin tags

Small, benign skin growths often found in areas of friction.

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Warts

Skin growths caused by viral infections.

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Cherry angioma

Small, red or purplish bumps caused by broken blood vessels.

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Ephelis (Freckles)

Small, flat brown spots that appear on sun-exposed skin.

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Lentigo Solar (Age Spots)

Darker spots on sun-exposed skin that increase with age.

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Melanocytic Naevi

Moles; Growth of melanocytes often in childhood.

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Tattoo

Introduction of pigment into the skin for decorative purposes.

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Malignant melanoma

A type of skin cancer that develops from melanocytes

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Basal Cell Carcinoma (BBC)

The most common skin cancer, slow-growing, rarely metastasizes.

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Squamous Cell Carcinoma (SCC)

Skin cancer arising from squamous cells, may metastasize.

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ABCDE signs of Melanoma

Malignant tumor characterized by asymmetry, irregular borders, color variation, diameter greater than 6mm, and evolution.

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Dermatitis Herpetiformis (treatment)

Itchy, vesicular skin manifestation related to Celiac Disease.

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Rosacea (causes)

Chronic inflammatory skin condition with redness, swelling, spots and blood vessels.

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Age with Pemphigus vulgaris

Younger

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Age with Bullous pemphigoid

Older

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Mucous membrane involvement with Pemphigus vulgaris

Yes

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Mucous membrane involvement with Bullous pemphigoid

Rare

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Autoantibodies with Pemphigus vulgaris

Against desmoglein 3

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Autoantibodies with Bullous pemphigoid

Against hemidesmosomes

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Nikolsky's sign with Pemphigus vulgaris

Nikolsky Positive

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Nikolsky's sign with Bullous pemphigoid

Nikolsky Negative

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Prognosis of Pemphigus vulgaris

Poor

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Prognosis of Bullous pemphigoid

Favourable

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Rosacea (description)

Common inflammatory skin condition with redness, swelling, spots and blood vessels.

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Urticaria (Causes)

Caused by food allergies

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Miliaria Pustulosa

A variant of Miliaria Rubra that involves pus-filled blisters.

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Miliaria Crystalline

Occurs close to the surface of the skin and is not itchy.

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Miliaria Profunda

Occurs deep into the skin and is the most uncommon form of heat rash.

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Miliaria Rubra (description)

Red bumps that occurs deeper in the outer layer of the skin

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Basal Cell Carcinoma prevention

Treat the area with high SPF sunscreen

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Squamous Cell Carcinoma (SCC) - causes

Tumor, UV radiation exposure and increased age.

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Squamous Cell Carcinoma - description

Squamous cells may commonly form on sun-exposed areas

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Dermoscope use

Enhances skin examination with magnification.

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Emulsifying ointments

Substances applied to soothe skin via moisture.

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Oatmeal baths

A type of bath to help irritation of the skin.

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Antihistamines

Medications counteracting histamine effects.

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Allergy tests (skin)

Tests that identifies triggers for skin changes.

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Chemical contact dermatitis

Rashes from elastic, latex or rubber.

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Natural chemical rashes

Rashes resulting contact to poison ivy or jelly fish.

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Animals sting rashes.

Skin changes from insect sting.

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Seborrheic dermatitis cause

Bacteria cause of scaling, redness, and itch.

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Impetigo cause

Causes inflammation and pus of staph aureus.

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Shingles Rash

A skin rash, often painful or itchy.

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Ephelis

Types of lesions affecting exposed skin with increased melanin.

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Letigo Solar

UV or radiation exposure, spots that rise with age.

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Contact Dermatitis

Inflammatory skin conditions involving hypersensitivity to substances.

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Insect bites & stings

Mosquitos, ticks and bees

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Shingles

Viral infection that causes painful rash along a nerve.

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Perioral Dermatitis

Steroid creams

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Lichen Planus

Immune system disorder with itchy, flat topped bumps.

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Rashes from Chemicals

Lesions caused by elastic, latex or rubber.

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Rashes from nature

Rash resulting from poison ivy or jelly fish.

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Malassezia

Disease where the skin is red and flaky

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Erythema Multiform Minor

This is a type of reaction, that does not involve the mucosa

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Measles infection

Occurs in childhood, rash and fever

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Childhood moles

Melanocytic Naevi- often form in childhood and congenital

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Study Notes

Skin vs. Oral Mucosa

  • Cutaneous epithelium includes the arrector pili muscle, sebum, sebaceous gland, and sweat gland.
  • Cutaneous epithelium permeability pathways are intracellular, transappendageal, transcellular, and through pores and hair follicles.
  • Oral mucosa consists of mucins, histatins, peptides, peroxidase, and growth factors.
  • The oral cavity exhibits saliva and salivary glands
  • Cutaneous epithelium functionality includes increased membrane permeability, cell proliferation, amino acid metabolism, angiogenesis, and scarring.
  • Oral mucosa functionality includes decreased membrane permeability, increased mechanical trauma, increased infection from bacteremia, and decreased inflammation and scarring

Describing Skin Conditions

  • Lesion: A single area of altered skin
  • Rash: A widespread eruption of lesions
  • Dermatosis: A generic term for a skin disease

Describing Skin Conditions - Morphology

  • Macule: Small & flat alteration in color
  • Patch: Large & smooth alteration in color
  • Papule: Elevated & solid, less than 1cm
  • Nodule: Elevated & solid, greater than 1cm
  • Cyst: Papule/nodule filled with fluid
  • Plaque: Circumscribed & possibly elevated, greater than 1cm
  • Vesicle: Small blister, less than 1cm
  • Bulla: Large blister, greater than 1cm
  • Pustule: Circumscribed & filled with pus
  • Abscess: Localized collection of pus
  • Erosion: Superficial/partial destruction of the epidermis
  • Fissure: Linear/narrow erosion/ulcer
  • Ulcer: Full loss of epidermis & portion of dermis +/- subcutaneous tissue
  • Atrophy: Reduction of epidermal +/- thickness
  • Crusting: Dried exudate (plasma, blood combo)

Skin Disorders - Examination, Investigations, General Management

  • Examination: Dermoscope
  • Investigations: Allergy tests, blood tests, swabs and smears, biopsy, and imaging
  • General management: Emulsifying ointments, oatmeal baths, antihistamines, topical/systemic steroids, antibiotics/antifungals, immunosuppressants, immunomodulators, and surgery

Skin Disorders - Head and Neck Focus

  • The text relates to skin disorders affecting the head and neck region
  • These disorders include rashes, benign tumors of the skin, pigmented lesions, and skin cancer

Rashes - Changes in Color, Texture, Feel of Skin Surface

  • Causes: Chemicals (latex, soaps, dyes, etc.), natural ingredients (poison ivy, stinging nettles), animals (jellyfish, insect bites/stings)
  • Symptoms: Blistering, redness, scaly or dry skin, blotchiness, swelling or inflammation, itchy skin, pain, infection of broken skin areas, shiny flat-topped bumps

Rashes

  • Types: Contact dermatitis, insect bites/stings, infection, seborrheic dermatitis, impetigo, shingles, childhood diseases, folliculitis, inflammatory skin conditions
  • Inflammatory skin conditions include: Acne, Rosacea and Perioral dermatitis.
  • Immune mediated: Lichen Planus, Psoriasis, Connective Tissue Disorders, Bullous Diseases, Dermatitis Herpetiformis, Allergies, Atopic Dermatitis, Urticaria and Heat.

Rashes - Contact Dermatitis

  • Causes: chemicals in elastic/latex/rubber, cosmetics, soaps, detergents, chemicals in clothing (dyes/other), natural chemicals (poison ivy, jellyfish)
  • Symptoms: Erythema, pruritus, vesicles, dryness

Rashes - Insect Bites

  • Caused by: Mosquitos, ticks, mites, lice, bees/wasps/hornets, fleas/flies/spiders.
  • Symptoms: Pain, swelling (lump), erythema, pruritus

Rashes - Seborrheic Dermatitis

  • Caused by: Malassezia (harmless yeast)
  • Localized: Scalp (dandruff), face, ears, torso, skin folds
  • Triggers: fatigue, stress, cold/dry weather
  • Symptoms: Erythema, Pruritus, flaking skin

Rashes - Impetigo

  • Caused by: Staph aureus, strep pyogenes
  • Common among children
  • May be either non-bullous or bullous
  • Symptoms: Erythematous lesions, cornflake crust, pruritus, pain

Rashes - Shingles

  • Caused by: Varicella-zoster virus
  • Secondary, latent
  • Symptoms: Headache, unwell feeling. Symptoms include rash restricted to one side, blisters that burst.

Rashes - Childhood Illnesses

  • Childhood illnesses include: Measles and German Measles

Rashes - Folliculitis

  • Folliculitis symptoms include Bumps/pimples around hair follicles, Pus-filled blisters that crust, Pruritus and Pain/ Burning.

Rashes - Acne

  • Acne symptoms include Spots, Oily skin and Hot Skin. The face, back and chest can be affected
  • Causes from Secondary bacterial infections, and Hormones/Genetics/Medications

Rashes - Rosacea

  • Rosacea Causes an unknown, common Triggers in include alcohol, spicy foods, hot drinks, sunlight, hot or cold temperatures, aerobic exercise, and being stressed are common triggers.

Rashes- Perioral Dermatitis

  • Related to steroids, Topical steroid creams or Inhaled prescription steroid sprays can contribute
  • Lifestyle choices, include heavy face creams and fluorinated Toothpaste and also caused by gum chewing and dental fillings.
  • Other is hormonal changes and dysfunction to the the epidermal barrier and related other cutaneous microflora or dermatitis.

Rashes - Immunological Mediated Disease - LP

  • LP includes Pruritus, Planar, Polygonal, Purple, Plaques, Papules
  • Classic lichen planus
  • Typical Appearances: Oral Lichen Planus and Violet- flat topped papules with nail scarring.

Rashes - Immunological Mediated Disease - Systemic Lupus Erythematosus (LE)

  • The condition involves an immune response that creates inflammation and leads to tissue damage. It can affect many body systems, including the joints, skin, kidneys, blood cells, brain, heart and lungs.
  • Types of cutaneous lupus erythematosus include acute cutaneous lupus, "butterfly rash," subacute cutaneous, and chronic cutaneous lupus.
  • Systemic lupus erythematosus triggers issues to heart, lungs, Kidney and Skin.
  • Diagnoses requires identifying ulcers

Rashes - Immunological Mediated Disease - EM

  • Erythema multiforme (EM) is a Type 4 hypersensitivity reaction
  • Skin lesions are acute, 24-48h appearance with distribution extremities (ears). They are often small around 3cm.
  • EM Minor has no mucosa involvement; EM Major involves one or more mucosa (e.g. eyes, GU, GI tract
  • The most common causes includes infections or Medications.

Benign Tumors of the Skin - Seborrheic Keratosis

  • Most common benign skin neoplasm
  • Unknown origin
  • More frequent with age

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