Skin & Soft Tissue Diseases - Dermatitis, Eczema, Urticaria, Psoriasis
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Questions and Answers

What is the pathogenesis of Psoriasis mainly characterized by?

  • Entrance of activated CD4+ T cells into the epidermis
  • Accumulation of B cells in the dermis
  • Enhanced fibroblast proliferation in the dermal layer
  • Secretion of cytokines and growth factors by CD8+ T cells (correct)
  • Which factor is NOT mentioned as a trigger for the appearance of Psoriasis?

  • Genetic predisposition
  • Myopathy (correct)
  • Various drugs
  • Environmental factors
  • What is the characteristic morphological change seen in the skin surface of patients with Psoriasis?

  • Roughening due to abnormal scale formation and shedding (correct)
  • Absence of lymphatic and blood-filled vascular spaces
  • Superficial dermal edema
  • Normal keratinocyte proliferation
  • Which statement accurately describes the clinical features of Psoriasis?

    <p>Psoriasis is a chronic inflammatory dermatosis</p> Signup and view all the answers

    Which of the following is NOT associated with Psoriasis according to the text?

    <p>Dilated lymphatic and blood-filled vascular spaces</p> Signup and view all the answers

    How are psoriatic lesions induced in susceptible individuals by local trauma known as?

    <p>Koebner phenomenon</p> Signup and view all the answers

    What is the main characteristic of acute dermatitis?

    <p>Formation of vesicles in the epidermis</p> Signup and view all the answers

    Which of the following best describes the pathogenesis of acute dermatitis?

    <p>Inflammatory cells infiltrating around blood vessels</p> Signup and view all the answers

    What is a common morphological change seen in acute dermatitis?

    <p>Swelling of the upper dermis</p> Signup and view all the answers

    Which clinical feature is typically associated with acute dermatitis?

    <p>Redness, tenderness, and itching</p> Signup and view all the answers

    In Psoriasis, what are some of the known causes?

    <p>Genetic factors</p> Signup and view all the answers

    Which best describes a common morphological change in Psoriasis?

    <p>Thickening and scaling of the skin</p> Signup and view all the answers

    What is a common characteristic of all forms of eczema?

    <p>Oozing and crusted lesions</p> Signup and view all the answers

    Which skin condition most commonly affects the hands?

    <p>Eczema</p> Signup and view all the answers

    What is the term used to describe a thin-walled sac filled with fluid in dermatology?

    <p>Vesicle</p> Signup and view all the answers

    Which skin condition is likely caused by a fungus in the oil glands?

    <p>Seborrheic Dermatitis</p> Signup and view all the answers

    What is reactive acanthosis and hyperkeratosis in eczema a result of?

    <p>Chronic inflammation</p> Signup and view all the answers

    Which term describes a solid or cystic raised spot on the skin that is less than 1 centimeter wide?

    <p>Papule</p> Signup and view all the answers

    Study Notes

    Psoriasis

    • Mainly characterized by an abnormal immune response that leads to rapid proliferation of skin cells
    • Triggered by factors such as genetic predisposition, environmental factors, and other medical conditions
    • NOT triggered by trauma

    Morphological Changes

    • Characteristic morphological change in Psoriasis: thickening of the epidermis (hyperkeratosis) and an increased number of skin cells (acanthosis)
    • In acute dermatitis: spongiosis (intercellular edema) and exocytosis (leukocyte migration into the epidermis)

    Clinical Features

    • Psoriasis: characterized by scaly, erythematous plaques and papules
    • Acute dermatitis: characterized by erythema, edema, and vesiculation
    • Eczema: characterized by dry, scaly, and itchy skin

    Lesions and Triggers

    • Psoriatic lesions induced in susceptible individuals by local trauma known as Köbner phenomenon
    • Acute dermatitis triggered by external factors such as allergens, irritants, and infections

    Other Skin Conditions

    • Eczema: a common morphological change is spongiosis and exocytosis
    • Fungal skin condition: likely caused by a fungus in the oil glands, such as in acne
    • Reactive acanthosis and hyperkeratosis in eczema result from an abnormal immune response
    • Vesicle: a thin-walled sac filled with fluid in dermatology
    • Papule: a solid or cystic raised spot on the skin that is less than 1 centimeter wide

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    Description

    Learn about dermatitis, eczema, urticaria, and psoriasis - their causes, pathogenesis, morphological changes, and clinical features. Specific learning outcomes include detailed descriptions of each skin condition.

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