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Questions and Answers
What is the pathogenesis of Psoriasis mainly characterized by?
What is the pathogenesis of Psoriasis mainly characterized by?
- Entrance of activated CD4+ T cells into the epidermis
- Accumulation of B cells in the dermis
- Enhanced fibroblast proliferation in the dermal layer
- Secretion of cytokines and growth factors by CD8+ T cells (correct)
Which factor is NOT mentioned as a trigger for the appearance of Psoriasis?
Which factor is NOT mentioned as a trigger for the appearance of Psoriasis?
- Genetic predisposition
- Myopathy (correct)
- Various drugs
- Environmental factors
What is the characteristic morphological change seen in the skin surface of patients with Psoriasis?
What is the characteristic morphological change seen in the skin surface of patients with Psoriasis?
- Roughening due to abnormal scale formation and shedding (correct)
- Absence of lymphatic and blood-filled vascular spaces
- Superficial dermal edema
- Normal keratinocyte proliferation
Which statement accurately describes the clinical features of Psoriasis?
Which statement accurately describes the clinical features of Psoriasis?
Which of the following is NOT associated with Psoriasis according to the text?
Which of the following is NOT associated with Psoriasis according to the text?
How are psoriatic lesions induced in susceptible individuals by local trauma known as?
How are psoriatic lesions induced in susceptible individuals by local trauma known as?
What is the main characteristic of acute dermatitis?
What is the main characteristic of acute dermatitis?
Which of the following best describes the pathogenesis of acute dermatitis?
Which of the following best describes the pathogenesis of acute dermatitis?
What is a common morphological change seen in acute dermatitis?
What is a common morphological change seen in acute dermatitis?
Which clinical feature is typically associated with acute dermatitis?
Which clinical feature is typically associated with acute dermatitis?
In Psoriasis, what are some of the known causes?
In Psoriasis, what are some of the known causes?
Which best describes a common morphological change in Psoriasis?
Which best describes a common morphological change in Psoriasis?
What is a common characteristic of all forms of eczema?
What is a common characteristic of all forms of eczema?
Which skin condition most commonly affects the hands?
Which skin condition most commonly affects the hands?
What is the term used to describe a thin-walled sac filled with fluid in dermatology?
What is the term used to describe a thin-walled sac filled with fluid in dermatology?
Which skin condition is likely caused by a fungus in the oil glands?
Which skin condition is likely caused by a fungus in the oil glands?
What is reactive acanthosis and hyperkeratosis in eczema a result of?
What is reactive acanthosis and hyperkeratosis in eczema a result of?
Which term describes a solid or cystic raised spot on the skin that is less than 1 centimeter wide?
Which term describes a solid or cystic raised spot on the skin that is less than 1 centimeter wide?
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Study Notes
Psoriasis
- Mainly characterized by an abnormal immune response that leads to rapid proliferation of skin cells
- Triggered by factors such as genetic predisposition, environmental factors, and other medical conditions
- NOT triggered by trauma
Morphological Changes
- Characteristic morphological change in Psoriasis: thickening of the epidermis (hyperkeratosis) and an increased number of skin cells (acanthosis)
- In acute dermatitis: spongiosis (intercellular edema) and exocytosis (leukocyte migration into the epidermis)
Clinical Features
- Psoriasis: characterized by scaly, erythematous plaques and papules
- Acute dermatitis: characterized by erythema, edema, and vesiculation
- Eczema: characterized by dry, scaly, and itchy skin
Lesions and Triggers
- Psoriatic lesions induced in susceptible individuals by local trauma known as Köbner phenomenon
- Acute dermatitis triggered by external factors such as allergens, irritants, and infections
Other Skin Conditions
- Eczema: a common morphological change is spongiosis and exocytosis
- Fungal skin condition: likely caused by a fungus in the oil glands, such as in acne
- Reactive acanthosis and hyperkeratosis in eczema result from an abnormal immune response
- Vesicle: a thin-walled sac filled with fluid in dermatology
- Papule: a solid or cystic raised spot on the skin that is less than 1 centimeter wide
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