18 Questions
What is the primary function of beta defensins in the skin?
To destroy microorganisms by disrupting their cell membranes
Which layer of the skin is primarily affected by dermatophyte infections like tinea or ringworm?
Epidermis
How does the dry environment of the skin help prevent infections?
Limits colonization by certain microorganisms
In deeper skin conditions like furuncles and carbuncles, where do these infections primarily invade?
Dermis
Which skin component is responsible for forming a waterproof barrier that blocks the entry of infectious agents?
Keratinocytes
What is the function of the stratum corneum in the skin?
To provide a protective layer made up of keratinocytes
What is the role of sebum in skin infection prevention?
It lowers skin pH, inhibiting many microorganisms.
Which of the following skin-resident immune cells is NOT involved in preventing skin infections?
Eosinophils
How do sweat glands contribute to preventing skin infections?
Produce lysozyme to break down bacterial cell walls.
Where do most of the skin microbiome reside within the skin structure?
Superficial stratum corneum and upper hair follicles
Which type of bacteria are key colonizers in the human skin microbiome?
Corynebacterium
How do skin normal flora help prevent pathogen colonization?
By blocking attachment to the skin surface
Which skin microorganism is the most prevalent?
Staphylococcus epidermidis
What type of bacteria are typically found in skin moist regions?
Gram-negative bacilli
Which of the following is a primary bacterial agent causing skin infections?
Propionibacterium acnes
Which toxin is responsible for Scalded Skin Syndrome?
Epidermolytic toxin
Impetigo, Scarlet fever, and Erysipelas are caused by which pathogenic bacteria?
Streptococcus pyogenes
What is the main fungus found on the skin according to the text?
Candida
Explore skin infections, skin defence mechanisms, and the skin microbiome in this overview. Learn about the structure of the skin, including the epidermis and dermis layers, and their relationship to infections. This content is presented by Malik Sallam, M.D., Ph.D., from the School of Medicine at The University of Jordan.
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