Skin Glands Anatomy and Function

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Questions and Answers

What is the name of the complex, oily mixture of lipids secreted by sebaceous glands?

Sebum

What type of secretion is sebum production an example of?

Holocrine secretion

Which of the following are components of the apocrine glands? (Select all that apply)

  • Merocrine exocytosis
  • Secretory simple cuboidal and eosinophilic cells (correct)
  • Simple cuboidal, eosinophilic cells with numerous secretory granules that show merocrine, not apocrine, secretion
  • Granules that are similar to those of the numerous secretory granules that also show merocrine, not apocrine, secretion (correct)

Apocrine sweat glands are largely confined to skin of the axillary and perineal regions.

<p>True (A)</p> Signup and view all the answers

The development of apocrine glands depends on sex hormones and is not complete until after puberty.

<p>True (A)</p> Signup and view all the answers

The ducts of apocrine glands are similar to those of the eccrine glands, but they usually open into hair follicles at the epidermis.

<p>True (A)</p> Signup and view all the answers

The slightly viscous secretion is initially odorless but may acquire a distinctive odor as a result of bacterial activity.

<p>True (A)</p> Signup and view all the answers

Apocrine sweat glands are innervated by cholinergic nerve endings.

<p>False (B)</p> Signup and view all the answers

Cystic fibrosis (CF) is a genetic disease that commonly affects infants with cystic fibrosis.

<p>False (B)</p> Signup and view all the answers

What is the type of transmembrane conductance regulator (CFTR) defect in cells that lead to disruptive accumulations of thick mucus in the respiratory and digestive tracts?

<p>CF patients have defects in a transmembrane conductance regulator (CFTR) of epithelial cells</p> Signup and view all the answers

Failure to remove salt from sweat is related to the same genetic defect as cystic fibrosis.

<p>True (A)</p> Signup and view all the answers

What is the process of cutaneous wound healing, whether initiated surgically or accidentally, exposed and easily damaged organ?

<p>Skin has a good capacity for repair, which is important in this exposed and easily damaged organ.</p> Signup and view all the answers

During the first phase with the size of the wound what happens?

<p>In the first phase with the size of the wound, the process of cutaneous wound healing involves several overlapping stages that vary in duration blood from cut vessels coagulates in the wound, releasing polypeptide growth factors and chemokines from the disintegrating platelets.</p> Signup and view all the answers

What happens during the second phase of wound healing?

<p>Neutrophils and macrophages undergo diapedesis locally and remove bacteria and debris from the wound.</p> Signup and view all the answers

Flashcards

Sebaceous Glands

Glands that secrete sebum, an oily substance released into hair follicles, via holocrine secretion.

Sebum

An oily mixture of lipids secreted by sebaceous glands.

Holocrine Secretion

A type of secretion where the entire cell disintegrates to release its product.

Apocrine Sweat Glands

Sweat glands primarily in axillary and perineal regions, functional after puberty.

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Eccrine Sweat Glands

Sweat glands that also remove waste and excess salts.

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CF Sweat

Salty sweat; an indicator of Cystic Fibrosis.

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Cystic Fibrosis (CF)

Genetic disease affecting mucus production and salt transport.

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CFTR

Transmembrane conductance regulator; faulty in cystic fibrosis.

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Skin Repair

Skin's ability to heal, crucial for injury recovery.

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Wound Healing

Process of repairing skin damage.

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Blood Coagulation

The process of blood clotting after an injury.

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Growth Factors & Chemokines

Proteins released by platelets to stimulate cell growth.

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Neutrophils

White blood cells that fight infection.

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Macrophages

Immune cells removing debris and bacteria.

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Myoepithelial Cells

Cells found in some glands that contract to push secretions.

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Study Notes

Sebaceous Glands

  • Secrete sebum, a complex oily mixture of lipids
  • Sebum is released into hair follicles
  • Sebaceous glands use holocrine secretion, where the entire cell dies and contributes to the product.
  • Sebaceous glands are made up of sebocytes
  • Sebocytes undergo terminal differentiation filling with lipids and then disintegrating near the ducts.

Eccrine Sweat Glands

  • Function as auxiliary excretory organs
  • Eliminate nitrogenous waste and excess salts
  • Located throughout the skin
  • Their development is not complete until puberty
  • Composed of simple cuboidal, eosinophilic cells with numerous secretory granules
  • Secrete a watery fluid through merocrine secretion.

Apocrine Sweat Glands

  • Primarily in axillary and perineal regions
  • Dependent on sex hormones for development
  • Their secretory components are larger than eccrine glands
  • Composed of simple cuboidal cells
  • Secrete a slightly viscous fluid
  • May contain proteins and pheromones
  • Their ducts usually open into hair follicles
  • Secrete via merocrine method

Medical Application of Sweat Glands

  • Infants with cystic fibrosis (CF) often have salty sweat
  • CF is a genetic disease affecting transmembrane conductance regulator (CFTR) in epithelial cells
  • CF leads to mucus build-up in respiratory and digestive tracts
  • Failure to remove salt from sweat is linked to the same genetic defect in CF.

Skin Repair

  • Skin has a good capacity for repair.
  • The process of wound healing is multi-stage.
  • The first stage involves blood clotting
  • Platelets releases growth factors and chemokines
  • Neutrophils and macrophages remove bacteria and debris.

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