Podcast
Questions and Answers
What is the most common cause of vaginitis?
What is the most common cause of vaginitis?
- Trichomonas vaginalis
- Bacterial vaginosis
- Human papillomavirus
- Candida albicans (correct)
Which of the following conditions can lead to an opportunistic infection by Candida albicans?
Which of the following conditions can lead to an opportunistic infection by Candida albicans?
- Uncontrolled diabetes (correct)
- High protein intake
- High-fat diet
- Dehydration
What are the characteristics of the discharge associated with trichomoniasis?
What are the characteristics of the discharge associated with trichomoniasis?
- Clear and odorless
- Thin and watery
- Thick, yellow, and cheesy
- Profuse, greenish yellow with a foul odor (correct)
Which treatment is commonly used for skin and mucosal infections caused by Candida albicans?
Which treatment is commonly used for skin and mucosal infections caused by Candida albicans?
What is a common symptom of vulvovaginal candidiasis?
What is a common symptom of vulvovaginal candidiasis?
Which statement about Trichomonas vaginalis is true?
Which statement about Trichomonas vaginalis is true?
What factor might disturb the normal acidity of the vagina and promote Trichomonas vaginalis overgrowth?
What factor might disturb the normal acidity of the vagina and promote Trichomonas vaginalis overgrowth?
How does Leishmania donovani affect the human body if left untreated?
How does Leishmania donovani affect the human body if left untreated?
What is the role of the female Anopheles mosquito in the transmission of malaria?
What is the role of the female Anopheles mosquito in the transmission of malaria?
Why are individuals with sickle cell trait less susceptible to malaria?
Why are individuals with sickle cell trait less susceptible to malaria?
Which stage of Plasmodium is responsible for infecting red blood cells?
Which stage of Plasmodium is responsible for infecting red blood cells?
What specific symptoms characterize malaria episodes?
What specific symptoms characterize malaria episodes?
What symptom is NOT commonly associated with coccidioidomycosis?
What symptom is NOT commonly associated with coccidioidomycosis?
Which factor contributes to the spread of Coccidioides immitis infection?
Which factor contributes to the spread of Coccidioides immitis infection?
What characteristic feature is formed by Coccidioides immitis in tissues during severe infections?
What characteristic feature is formed by Coccidioides immitis in tissues during severe infections?
What is the primary habitat for Histoplasma capsulatum to thrive?
What is the primary habitat for Histoplasma capsulatum to thrive?
How does Histoplasma capsulatum survive and multiply in the human body?
How does Histoplasma capsulatum survive and multiply in the human body?
What would increase the likelihood of severe infection by Coccidioides immitis?
What would increase the likelihood of severe infection by Coccidioides immitis?
In cases where Coccidioides immitis spreads systematically, how can it resemble a different disease?
In cases where Coccidioides immitis spreads systematically, how can it resemble a different disease?
What aspect of birds allows them to provide nutrients for Histoplasma capsulatum without carrying the disease?
What aspect of birds allows them to provide nutrients for Histoplasma capsulatum without carrying the disease?
Which group of individuals is most likely to show prior infection with Coccidioides immitis based on the skin test?
Which group of individuals is most likely to show prior infection with Coccidioides immitis based on the skin test?
What is a potential complication of a respiratory infection caused by the fungus carried by bats?
What is a potential complication of a respiratory infection caused by the fungus carried by bats?
How does Pneumocystis jirovecii primarily invade the body?
How does Pneumocystis jirovecii primarily invade the body?
Which population is at higher risk for severe infections caused by Pneumocystis jirovecii?
Which population is at higher risk for severe infections caused by Pneumocystis jirovecii?
What unique reproductive feature is associated with the lifecycle of Pneumocystis jirovecii?
What unique reproductive feature is associated with the lifecycle of Pneumocystis jirovecii?
What is the typical entry point for Blastomyces dermatitidis in an infection?
What is the typical entry point for Blastomyces dermatitidis in an infection?
What is a significant challenge in treating infections caused by Pneumocystis jirovecii?
What is a significant challenge in treating infections caused by Pneumocystis jirovecii?
In which organ are significant microbial lesions found during a severe Pneumocystis infection?
In which organ are significant microbial lesions found during a severe Pneumocystis infection?
What characteristic of the fungus associated with bat feces makes it particularly concerning for cave explorers?
What characteristic of the fungus associated with bat feces makes it particularly concerning for cave explorers?
What might happen if a healthy individual's immune response to Pneumocystis jirovecii is inadequate?
What might happen if a healthy individual's immune response to Pneumocystis jirovecii is inadequate?
Why did hospitals notice an increase in lung fungal infections in the early 1980s among young people?
Why did hospitals notice an increase in lung fungal infections in the early 1980s among young people?
What is the primary method by which Cyclosporiasis is typically spread?
What is the primary method by which Cyclosporiasis is typically spread?
Which condition can lead to more severe symptoms of Cyclosporiasis?
Which condition can lead to more severe symptoms of Cyclosporiasis?
Which species primarily causes Cryptosporidiosis in humans?
Which species primarily causes Cryptosporidiosis in humans?
How is Cryptosporidiosis primarily transmitted?
How is Cryptosporidiosis primarily transmitted?
What type of diarrhea is most commonly associated with Cryptosporidiosis?
What type of diarrhea is most commonly associated with Cryptosporidiosis?
Which of the following organisms is known to cause life-threatening diarrhea in immunocompromised individuals?
Which of the following organisms is known to cause life-threatening diarrhea in immunocompromised individuals?
What is a major environmental source of contamination for Cryptosporidiosis?
What is a major environmental source of contamination for Cryptosporidiosis?
What is the main vector responsible for spreading Visceral Leishmaniasis?
What is the main vector responsible for spreading Visceral Leishmaniasis?
Which of the following is a common effect of Cyclospora infection?
Which of the following is a common effect of Cyclospora infection?
Which treatment method is typically needed to remove oocysts from drinking water?
Which treatment method is typically needed to remove oocysts from drinking water?
Flashcards
Vulvovaginal Candidiasis
Vulvovaginal Candidiasis
A fungal infection affecting the vagina and vulva caused by Candida albicans, characterized by itching, thick cheesy discharge, and possibly a yeasty odor.
Candida albicans infection
Candida albicans infection
An opportunistic infection that can occur due to factors like uncontrolled diabetes, pH changes, hormone fluctuations, and long-term antibiotic use.
Trichomoniasis
Trichomoniasis
A sexually transmitted infection caused by the protozoan Trichomonas vaginalis, often asymptomatic but can cause a greenish-yellow, foul-smelling discharge, irritation, and itching.
Trichomonas vaginalis
Trichomonas vaginalis
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T. hominis
T. hominis
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T. tenax
T. tenax
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Gonorrhea
Gonorrhea
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Pneumocystis pneumonia (PCP)
Pneumocystis pneumonia (PCP)
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Blastomycosis
Blastomycosis
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Bat-Associated Fungal Infection
Bat-Associated Fungal Infection
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PCP in Immunocompromised Individuals
PCP in Immunocompromised Individuals
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Dissemination of Fungal Infection
Dissemination of Fungal Infection
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Coccidioidomycosis
Coccidioidomycosis
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Spores of Coccidioides immitis
Spores of Coccidioides immitis
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Filamentous form of Coccidioides immitis
Filamentous form of Coccidioides immitis
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Spherule of Coccidioides immitis
Spherule of Coccidioides immitis
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Histoplasmosis
Histoplasmosis
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Conidia of Histoplasma capsulatum
Conidia of Histoplasma capsulatum
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Yeast form of Histoplasma capsulatum
Yeast form of Histoplasma capsulatum
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Macrophage
Macrophage
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Bird and bat droppings and Histoplasmosis
Bird and bat droppings and Histoplasmosis
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Leishmania donovani
Leishmania donovani
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Leishmaniasis
Leishmaniasis
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Plasmodium vivax
Plasmodium vivax
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Malaria
Malaria
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Sporozoite stage
Sporozoite stage
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Cyclosporiasis
Cyclosporiasis
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Cryptosporidium
Cryptosporidium
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Cryptosporidium Oocysts
Cryptosporidium Oocysts
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Cryptosporidiosis
Cryptosporidiosis
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Importance of Water Filtration
Importance of Water Filtration
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Visceral Leishmaniasis
Visceral Leishmaniasis
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Cyclospora Oocysts
Cyclospora Oocysts
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Cyclosporiasis
Cyclosporiasis
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Visceral Leishmaniasis
Visceral Leishmaniasis
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Cryptosporidium Life Cycle
Cryptosporidium Life Cycle
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Study Notes
Skin Diseases
- Fungi that invade keratinized tissue (epidermis) colonize hair, nails and outer layer (stratum corneal), causing dermatomycoses (fungal skin infections) also known as tinea or ringworm.
- Mycoses refers to fungal cells targeting skin cells.
- Fungal and protozoal organisms have complex life cycles, making them resistant to anti-fungal/protozoal drugs.
- Immunocompromised individuals (like those with HIV) are more vulnerable to fungal infections.
- Ringworm presents as circular lesions, commonly on the scalp.
- Tinea corporis, cruris, capitis, and unguium are contagious and transmittable through unclean environments and inanimate objects (fomites).
- Tinea capitis (scalp ringworm) is common in elementary school-aged children, potentially causing bald patches.
- Dogs and cats can also get ringworm, which can spread to children.
- Tinea cruris/jock itch affects the groin area
- Tinea pedis/athlete's foot affects the feet, potentially leading to secondary bacterial infections in moist environments like shoes.
- Tinea unguium/onychomycosis affects fingernails or toenails.
- Antifungal drugs are used to treat these infections, but treatment may take several weeks due to the organism's complex life cycle.
Opportunistic Fungal Infections
- Candida albicans is a part of normal flora in the mouth and vagina.
- Antibiotics can disrupt normal flora, allowing Candida to overgrow and cause candidiasis, which can have no competition.
- Fungal overgrowth in mucosal tissue due to antibiotic use can lead to candidiasis.
- Changes in mucosal pH can also lead to candidiasis.
- Candidiasis can cause thrush (oral cavity overgrowth), vaginitis, and infection of other tissues.
- Candidiasis is one of the most common nosocomial (hospital-acquired) fungal infections.
- Candida auris is a concerning emerging fungal infection, which is difficult to grow in normal media and is resistant to many common antifungal drugs.
- Candida auris is highly resistant to antifungal drugs, and can cause serious bloodstream infections in hospitalized patients.
Vulvovaginal Candidiasis
- Vulvovaginal candidiasis is a common vaginal infection caused by Candida albicans.
- It can occur in individuals with uncontrolled diabetes, hormonal changes, or long-term antibiotic therapy.
- The condition is characterized by itching, a thick, yellow discharge, and a yeasty odor.
- Candida albicans infects mucous membranes of the mouth, intestinal tract, and genitourinary tract.
- Treatment typically involves topical antifungal drugs like miconazole or clotrimazole.
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