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Skin Anatomy and Atopic Dermatitis

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Questions and Answers

What percentage of the epidermis is composed of keratinocytes?

80%
70%
90% (correct)
60%

What is the primary function of the cornified outer layer of skin?

To aid in wound healing
To produce melanin
To regulate body temperature
To provide an impermeable barrier (correct)

What percentage of atopic dermatitis patients will develop asthma or allergies by their third birthday?

70%
80%
50% (correct)
30%

What is the primary function of defensins in sweat?

To exhibit anti-microbial properties (B) Signup and view all the answers

What is the name of the cells that produce melanin in the epidermis?

Melanocytes (B) Signup and view all the answers

What is the approximate percentage of atopic dermatitis patients with high levels of IgE to common environmental or food allergens?

80% (D) Signup and view all the answers

What is the result of decreased expression of filaggrin in atopic dermatitis?

Increased transepidermal water loss (TEWL) (B) Signup and view all the answers

What is the effect of Th2 cell cytokines on antimicrobial peptides?

Decrease production of antimicrobial peptides (A) Signup and view all the answers

What is the role of IgE in atopic dermatitis?

To induce histamine release and the itch-scratch cycle (C) Signup and view all the answers

What is the effect of physiological stress on lipid production?

Decrease lipid production (C) Signup and view all the answers

What is the role of staphylococcus aureus superantigens?

To bind to IgE and induce histamine release (C) Signup and view all the answers

What is a treatment option for mild atopic dermatitis?

All of the above (D) Signup and view all the answers