21 Questions
Why is size reduction important in the pharmaceutical manufacturing process?
To achieve the required size for incorporation into finished products
What characterizes the solid produced during raw material manufacture?
Larger size than required pharmaceutically
What can conventional particle technologies sometimes lead to for drugs?
Thermal and chemical degradation
What is a common result of conventional particle technologies in terms of particle size?
Non-uniform sized particles
Which of the following correct improvements brought by size reduction in pharmaceutical formulation except?
Enhancement of tablet hardness
What is a disadvantage of PSR related to the active ingredient?
Possible change in polymorphic form rendering it less or totally inactive or unstable
Friable materials: Sucrose and dried filter cakes are friable (i.e. brittle) hence they are easy to comminute by hammer mill or fluid energy mill.
True
True or false: Particle size of the feed: For a mill to operate satisfactorily, the feed should be of proper size.
True
True or false: the harder the material the more difficult it is to reduce in size.
True
True or false: Moderately coarse powders may be obtained from various impact mill.
True
which of the following correct selection of size reduction equipment except?
All of the above
Which of the following correct Classification of Size Reduction equipment based on the resultant particle size?
All of the above
Which of the following correct All milling or comminution equipment consist basic part except?
Screen
Which of the following advantage of the Hammer mill except:
The rate of feed must be controlled carefully as the mill may be choked, resulting in decreased efficiency or even damage.
True or false: pharmaceutical ingredients, bulk pharmaceutical ingredients and excipients such as lactose, HPMC and others.
True
True or false: Mills produce intermediate particles consist : Hammer mill and Cutter mill?
True
True or false: Hammer mill is used for grinding or pulverizing solid or granular materials primarily used in cosmetic industries.
True
What is the function of the stationary knives in the equipment?
Cutting the material into pieces
Where does the feed enter in this equipment?
Through the top hopper
What is the purpose of the screen in the lower part of the equipment?
To retain material until sufficient size reduction
Which of the following correct pharmaceutical use of Cutter Mill except ?
Rotor size
Learn about the importance of size reduction in pharmaceutical manufacturing and the different mechanisms and equipment used for this process.
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