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Which of the is the first sign of shock that usually appears in patients
Which of the is the first sign of shock that usually appears in patients
A tachypneic 17 year old male has an open gunshot wound to the right anterior chest. What should you do?
A tachypneic 17 year old male has an open gunshot wound to the right anterior chest. What should you do?
A 34 year old male was hit in the chest with a baseball bat. Portions of his chest move in opposite directions when he breathes. What should you suspect?
A 34 year old male was hit in the chest with a baseball bat. Portions of his chest move in opposite directions when he breathes. What should you suspect?
What is a contraindication of a traction splint?
What is a contraindication of a traction splint?
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An alert 75 year old male after slipped on his wet sidewalk. He is sober and denies hitting his head. He states his legs just went out from under him and he fell to his right knee. His right leg is internally rotated and shortened. Vital signs are BP 110/40, P 96, R 18. What should you suspect?
An alert 75 year old male after slipped on his wet sidewalk. He is sober and denies hitting his head. He states his legs just went out from under him and he fell to his right knee. His right leg is internally rotated and shortened. Vital signs are BP 110/40, P 96, R 18. What should you suspect?
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If transport is delayed or prolonged, and if circulation is impaired, an attempt should be made to reposition a grossly deformed fracture or dislocated joint (if allowed by medical control or protocol). The exception is an injury to the _____
If transport is delayed or prolonged, and if circulation is impaired, an attempt should be made to reposition a grossly deformed fracture or dislocated joint (if allowed by medical control or protocol). The exception is an injury to the _____
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A factory worker has a 3/4 inch laceration on his forehead that bleeds through the dressings despite direct pressure. What should you do?
A factory worker has a 3/4 inch laceration on his forehead that bleeds through the dressings despite direct pressure. What should you do?
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A 20 year old female has burns on her chest, abdomen, and on the anterior side of her right arm. What percentage of body is burned?
A 20 year old female has burns on her chest, abdomen, and on the anterior side of her right arm. What percentage of body is burned?
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What is the correct technique when splinting a suspected finger fracture?
What is the correct technique when splinting a suspected finger fracture?
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A 50 year old female presents with narrow complex tachycardia and has the following signs and symptoms: respiratory rate of 22 and non labored, BP of 117/68, radial pulse rate of 176 strong and regular, and skin is pink, warm, and dry. What would be the most appropriate first treatment.
A 50 year old female presents with narrow complex tachycardia and has the following signs and symptoms: respiratory rate of 22 and non labored, BP of 117/68, radial pulse rate of 176 strong and regular, and skin is pink, warm, and dry. What would be the most appropriate first treatment.
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Match the following medications with their primary usage:
Match the following medications with their primary usage:
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Match the following properties with the corresponding medication class:
Match the following properties with the corresponding medication class:
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Match the following characteristics with the appropriate medication effects:
Match the following characteristics with the appropriate medication effects:
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Match the following medications with their primary usage in emergency situations:
Match the following medications with their primary usage in emergency situations:
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Match the following medications with their effects on patients:
Match the following medications with their effects on patients:
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Match the following medications with their characteristics:
Match the following medications with their characteristics:
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Match the following medications with their specific applications:
Match the following medications with their specific applications:
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Which of the following is NOT a characteristic sign of inflammation?
Which of the following is NOT a characteristic sign of inflammation?
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Which process is responsible for dissolving excess clots by breaking down cross-linked fibrin strands?
Which process is responsible for dissolving excess clots by breaking down cross-linked fibrin strands?
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What are the chemical signals released by cells lining blood vessels that increase capillary permeability?
What are the chemical signals released by cells lining blood vessels that increase capillary permeability?
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What role does the immune system play in the inflammatory response?
What role does the immune system play in the inflammatory response?
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What is the function of memory within the immune system in the context of inflammation?
What is the function of memory within the immune system in the context of inflammation?
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Study Notes
Essential Medications for Paramedics
- Analgesic medications relieve pain without causing unconsciousness, with examples including morphine sulfate (powerful relief from moderate to severe pain with sedating effects) and fentanyl citrate (faster-acting alternative with higher potency).
- Antiemetic medications prevent nausea and vomiting, with examples including promethazine (Phenergan, used for motion sickness, postoperative nausea, or chemotherapy-related emesis, but with side effects like drowsiness) and dexamethasone (quick relief from acute nausea).
- Anticholinergic medications are used by paramedics, with examples including atropine (treats bradycardia caused by overdoses or other underlying issues) and glycopyrrolate (safer alternative for cases where heart rhythm isn't affected).
- Bronchodilator medications relax smooth muscle tissue lining airways, allowing them to dilate and improve breathing, with examples including salbutamol (quick treatment of asthma exacerbations) and ipratropium bromide (provides prolonged action for patients who continue to experience wheezing).
- Vasopressor medications raise blood pressure levels by increasing peripheral vascular resistance, with examples including ephedrine (less frequently used due to risks associated with excessive catecholamine release), phenylephrine, and norepinephrine (primary options for treating shock states).
The Extrinsic Pathway
- The extrinsic pathway initiates hemostasis outside blood vessels due to tissue disruption, involving the interaction between tissue factors (TF) and circulating VII (tissue factor pathway inhibitor-dependent) or IX and X (tissue factor pathway inhibitor-independent).
- Tissue factor binds with its specific receptor, factor VII, forming a TF-VIIa complex, which activates factors X and IX, leading to prothrombin conversion to thrombin.
Understanding Clotting Cascades
- The human body relies on two interconnected mechanisms, the intrinsic and extrinsic pathways of blood coagulation, to prevent excessive bleeding while maintaining proper circulation.
- The intrinsic pathway is initiated through contact with negatively charged surfaces, primarily contributing to coagulation after vascular injury.
- The extrinsic pathway starts with the exposure of blood to tissue factor released by injured cells.
The Intrinsic Pathway
- The intrinsic pathway involves the interaction between factor XII, prekallikrein, high molecular weight kininogen, and endothelial cell surface receptors known as thrombomodulin.
- Factor XII gets activated, converting prekallikrein into kallikrein, which activates factor XI, leading to the activation of factor IX and subsequent protein conversions.
The Common Pathway
- The common pathway is the final phase where the intrinsic and extrinsic pathways merge, involving the formation of the prothrombinase complex, which catalyzes the transformation of prothrombin to thrombin.
- Thrombin catalyzes the production of fibrin strands, ultimately forming a stable clot.
Coagulation Factors
- There are twelve coagulation factors participating in the clotting cascade, each playing specific roles in generating or inhibiting clots.
- Factors serve as precursors of enzymes required for clot initiation or help control thrombin activity or prevent abnormal clot growth.
Fibrinolysis
- Fibrinolysis is the process of dissolving excess clots via the action of plasmin, which breaks down cross-linked fibrin strands back to their original constituents.
- Plasminogens convert to active plasmins through a series of activators such as tPA (tissue plasminogen activator) and urokinase-type plasminogen activator (uPA).
Understanding Inflammation
- Inflammation is a complex biological process serving as one of the body's primary defense mechanisms against disease, infection, injury, and cellular dysfunction.
- The inflammatory response involves multiple signaling cascades within cells, classified into innate immunity pathways and adaptive immunity pathways.
Inflammation Pathways
- Innate immunity pathways represent a frontline defense mechanism activated by macrophages, neutrophils, dendritic cells, and natural killer cells upon encountering foreign invaders.
- Adaptive immunity pathways lead to highly specific responses tailored to target particular antigens once introduced to the body.
Acute Inflammation
- Acute inflammation is a rapid localized reaction lasting hours to days following tissue injury or infection, characterized by redness, warmth, swelling, and pain.
- Cells lining blood vessels release chemical signals called vasoactive amines, increasing capillary permeability and attracting leukocytes, leading to fluid accumulation around injured areas.
Cytokines
- Cytokines are critical messengers within the inflammatory response, regulating and coordinating various aspects of immune function.
- They exist in both pro-inflammatory and anti-inflammatory forms, allowing for dynamic control over the extent and duration of inflammation.
- Key examples of cytokines associated with acute inflammation include tumor necrosis factor alpha (TNF-α), interleukin-1 beta (IL-1β), IL-6, and IL-8.
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Description
Test your knowledge on identifying the first sign of shock that typically appears in patients. Learn about the initial symptoms that indicate the onset of shock.