Haemolytic Anaemia Quiz for Class Year 1 Students at RCSI

Play an AI-generated podcast conversation about this lesson

Which of the following is an intrinsic cause of haemolytic anaemia?

Iron deficiency

G-6PD deficiency (correct)

Chronic disease

Autoimmune disorder

Which of the following is an extrinsic cause of haemolytic anaemia?

Autoimmune disorder (correct)

Thalassaemia

Sickle cell disease

Hereditary spherocytosis

What are the consequences of haemolytic anaemia?

Low levels of bilirubin and LDH

Asymptomatic condition

Increased production of red blood cells

High levels of bilirubin and LDH (correct)

Which type of autoimmune hemolytic anemia is characterized by an IgG autoantibody and is associated with lymphoma and collagen vascular diseases?

Warm antibody AIHA Signup and view all the answers

What are the typical laboratory findings in the diagnosis of autoimmune hemolytic anemia?

Reticulocytosis and indirect hyperbilirubinemia Signup and view all the answers

What are some common precipitating factors for sickling in sickle cell disease?

All of the above Signup and view all the answers

What is the main function of haptoglobin in the body?

To mop up degenerative fragments of RBCs Signup and view all the answers

Which of the following is NOT a microorganism discussed in the text?

Arthropods Signup and view all the answers

What is the term used to describe microorganisms that temporarily reside in the human body?

Transient Signup and view all the answers

Which discipline overlaps with clinical microbiology and is associated with peptic ulcer disease?

Bacteriology Signup and view all the answers

Which of the following is NOT a category of parasitic worms?

Mosquitoes Signup and view all the answers

Which of the following diseases is caused by prions?

CJD Signup and view all the answers

Which of the following terms describes the presence of microorganisms on a body surface without causing damage to the host?

Colonization Signup and view all the answers

Which of the following is NOT a component of the human microbiome?

Prions Signup and view all the answers

What is the classification of fungi based on their cellular structure?

Eukaryotes Signup and view all the answers

Which of the following is NOT a characteristic of viruses?

They can produce their own metabolic energy Signup and view all the answers

What is the main characteristic of protozoa?

They can produce their own metabolic energy Signup and view all the answers

What is the purpose of phenotypic analysis in microbiology?

To study the physical characteristics of an organism Signup and view all the answers

Which of the following is NOT a predominant species in the large intestine?

Bifidobacterium bifidum Signup and view all the answers

Which of the following is NOT a characteristic of the genitourinary tract microbiome?

High resistance to infection Signup and view all the answers

Which of the following is a potential risk factor for disruption of the microbiome?

Underlying causes such as malnutrition Signup and view all the answers

What is the main purpose of faecal microbiota transplant (FMT)?

To replace a dysfunctional microbiome Signup and view all the answers

Which enzyme is involved in initiating replication and associates tightly with primase to make a Pol a/primase complex?

Pol a Signup and view all the answers

Which enzyme is responsible for leading strand synthesis in eukaryotic DNA replication?

Pol e Signup and view all the answers

Which enzyme is involved in primer removal and fills gaps during DNA replication?

Pol d Signup and view all the answers

Which enzyme is responsible for replicating mitochondrial DNA?

Pol g Signup and view all the answers

Which of the following proteins is responsible for separating the DNA strands in DNA replication?

DNA Helicase Signup and view all the answers

What is the role of Single-Strand Binding (SSB) proteins in DNA replication?

To prevent the DNA strands from re-associating Signup and view all the answers

Which enzyme is responsible for regulating the twisting of the DNA during DNA replication?

Topoisomerase Signup and view all the answers

Which enzyme is responsible for synthesizing RNA primers during DNA replication?

Primase Signup and view all the answers

Which enzyme is responsible for identifying and removing damaged bases in DNA?

DNA glycosylase Signup and view all the answers

Which repair mechanism is responsible for replacing regions of damaged DNA of up to 30 bases in length?

Nucleotide excision repair Signup and view all the answers

Which disorder is characterized by extreme sensitivity to light, skin cancer, and frequent secondary tumors?

Xeroderma Pigmentosum Signup and view all the answers

Which repair mechanism is associated with predisposition to cancer and immunodeficiency syndromes?

Nonhomologous end-joining Signup and view all the answers

Which of the following accurately describes the process of DNA replication in eukaryotes?

DNA replication in eukaryotes involves the disassembly and reassembly of nucleosomes. Signup and view all the answers

Which of the following accurately describes the role of Telomerase in DNA replication?

Telomerase adds new nucleotides to the growing DNA strand. Signup and view all the answers

Which of the following accurately describes the time required for DNA replication in different organisms?

DNA replication is faster in yeast compared to human cells. Signup and view all the answers