Haemolytic Anaemia Quiz for Class Year 1 Students at RCSI
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Questions and Answers

Which of the following is an intrinsic cause of haemolytic anaemia?

  • Iron deficiency
  • G-6PD deficiency (correct)
  • Chronic disease
  • Autoimmune disorder

    • Which of the following is an extrinsic cause of haemolytic anaemia?

  • Autoimmune disorder (correct)
  • Thalassaemia
  • Sickle cell disease
  • Hereditary spherocytosis

    • What are the consequences of haemolytic anaemia?

  • Low levels of bilirubin and LDH
  • Asymptomatic condition
  • Increased production of red blood cells
  • High levels of bilirubin and LDH (correct)

    • Which type of autoimmune hemolytic anemia is characterized by an IgG autoantibody and is associated with lymphoma and collagen vascular diseases?

    <p>Warm antibody AIHA (D)</p> Signup and view all the answers

    What are the typical laboratory findings in the diagnosis of autoimmune hemolytic anemia?

    <p>Reticulocytosis and indirect hyperbilirubinemia (D)</p> Signup and view all the answers

    What are some common precipitating factors for sickling in sickle cell disease?

    <p>All of the above (D)</p> Signup and view all the answers

    What is the main function of haptoglobin in the body?

    <p>To mop up degenerative fragments of RBCs (D)</p> Signup and view all the answers

    Which of the following is NOT a microorganism discussed in the text?

    <p>Arthropods (D)</p> Signup and view all the answers

    What is the term used to describe microorganisms that temporarily reside in the human body?

    <p>Transient (D)</p> Signup and view all the answers

    Which discipline overlaps with clinical microbiology and is associated with peptic ulcer disease?

    <p>Bacteriology (B)</p> Signup and view all the answers

    Which of the following is NOT a category of parasitic worms?

    <p>Mosquitoes (C)</p> Signup and view all the answers

    Which of the following diseases is caused by prions?

    <p>CJD (B)</p> Signup and view all the answers

    Which of the following terms describes the presence of microorganisms on a body surface without causing damage to the host?

    <p>Colonization (C)</p> Signup and view all the answers

    Which of the following is NOT a component of the human microbiome?

    <p>Prions (D)</p> Signup and view all the answers

    What is the classification of fungi based on their cellular structure?

    <p>Eukaryotes (D)</p> Signup and view all the answers

    Which of the following is NOT a characteristic of viruses?

    <p>They can produce their own metabolic energy (B)</p> Signup and view all the answers

    What is the main characteristic of protozoa?

    <p>They can produce their own metabolic energy (D)</p> Signup and view all the answers

    What is the purpose of phenotypic analysis in microbiology?

    <p>To study the physical characteristics of an organism (B)</p> Signup and view all the answers

    Which of the following is NOT a predominant species in the large intestine?

    <p>Bifidobacterium bifidum (A)</p> Signup and view all the answers

    Which of the following is NOT a characteristic of the genitourinary tract microbiome?

    <p>High resistance to infection (C)</p> Signup and view all the answers

    Which of the following is a potential risk factor for disruption of the microbiome?

    <p>Underlying causes such as malnutrition (B)</p> Signup and view all the answers

    What is the main purpose of faecal microbiota transplant (FMT)?

    <p>To replace a dysfunctional microbiome (D)</p> Signup and view all the answers

    Which enzyme is involved in initiating replication and associates tightly with primase to make a Pol a/primase complex?

    <p>Pol a (B)</p> Signup and view all the answers

    Which enzyme is responsible for leading strand synthesis in eukaryotic DNA replication?

    <p>Pol e (B)</p> Signup and view all the answers

    Which enzyme is involved in primer removal and fills gaps during DNA replication?

    <p>Pol d (C)</p> Signup and view all the answers

    Which enzyme is responsible for replicating mitochondrial DNA?

    <p>Pol g (A)</p> Signup and view all the answers

    Which of the following proteins is responsible for separating the DNA strands in DNA replication?

    <p>DNA Helicase (D)</p> Signup and view all the answers

    What is the role of Single-Strand Binding (SSB) proteins in DNA replication?

    <p>To prevent the DNA strands from re-associating (D)</p> Signup and view all the answers

    Which enzyme is responsible for regulating the twisting of the DNA during DNA replication?

    <p>Topoisomerase (D)</p> Signup and view all the answers

    Which enzyme is responsible for synthesizing RNA primers during DNA replication?

    <p>Primase (D)</p> Signup and view all the answers

    Which enzyme is responsible for identifying and removing damaged bases in DNA?

    <p>DNA glycosylase (D)</p> Signup and view all the answers

    Which repair mechanism is responsible for replacing regions of damaged DNA of up to 30 bases in length?

    <p>Nucleotide excision repair (B)</p> Signup and view all the answers

    Which disorder is characterized by extreme sensitivity to light, skin cancer, and frequent secondary tumors?

    <p>Xeroderma Pigmentosum (D)</p> Signup and view all the answers

    Which repair mechanism is associated with predisposition to cancer and immunodeficiency syndromes?

    <p>Nonhomologous end-joining (C)</p> Signup and view all the answers

    Which of the following accurately describes the process of DNA replication in eukaryotes?

    <p>DNA replication in eukaryotes involves the disassembly and reassembly of nucleosomes. (B)</p> Signup and view all the answers

    Which of the following accurately describes the role of Telomerase in DNA replication?

    <p>Telomerase adds new nucleotides to the growing DNA strand. (C)</p> Signup and view all the answers

    Which of the following accurately describes the time required for DNA replication in different organisms?

    <p>DNA replication is faster in yeast compared to human cells. (B)</p> Signup and view all the answers

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