Podcast
Questions and Answers
What is a result of decreased cardiac output and hypotension?
What is a result of decreased cardiac output and hypotension?
What helps return blood to the heart?
What helps return blood to the heart?
What is distributive shock caused by?
What is distributive shock caused by?
What is anaphylactic shock characterized by?
What is anaphylactic shock characterized by?
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What can cause neurogenic shock?
What can cause neurogenic shock?
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What is septic shock a response to?
What is septic shock a response to?
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What is a characteristic of neurogenic shock?
What is a characteristic of neurogenic shock?
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What can cause respiratory distress in anaphylactic shock?
What can cause respiratory distress in anaphylactic shock?
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What is the primary outcome of inadequate tissue perfusion during shock?
What is the primary outcome of inadequate tissue perfusion during shock?
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What is the primary reason for hypovolemic shock?
What is the primary reason for hypovolemic shock?
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What is the main cause of cardiogenic shock?
What is the main cause of cardiogenic shock?
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What is the primary goal of managing shock and hemorrhage in emergency and trauma situations?
What is the primary goal of managing shock and hemorrhage in emergency and trauma situations?
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What is the definition of shock according to Sole, Klein, and Moseley (2017)?
What is the definition of shock according to Sole, Klein, and Moseley (2017)?
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What is the term for the movement of fluid from the vascular space to the extravascular space?
What is the term for the movement of fluid from the vascular space to the extravascular space?
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What is the average pressure at which blood moves through the vasculature to perfuse vital organs?
What is the average pressure at which blood moves through the vasculature to perfuse vital organs?
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What is the outcome of shock if left untreated?
What is the outcome of shock if left untreated?
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What is the primary function of the circulatory system in relation to shock?
What is the primary function of the circulatory system in relation to shock?
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What is the term for shock that occurs when there is a physical impairment to adequate circulatory blood flow?
What is the term for shock that occurs when there is a physical impairment to adequate circulatory blood flow?
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What are the primary effects of shock on the body?
What are the primary effects of shock on the body?
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What is the leading cause of death from acute myocardial infarction (MI)?
What is the leading cause of death from acute myocardial infarction (MI)?
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What is the primary goal of nursing management in shock?
What is the primary goal of nursing management in shock?
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What is necessary for tissue perfusion?
What is necessary for tissue perfusion?
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What is the definition of shock according to Brunner et al. (2004)?
What is the definition of shock according to Brunner et al. (2004)?
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What is an example of a cause of obstructive shock?
What is an example of a cause of obstructive shock?
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What percentage of sepsis cases and sepsis-related deaths worldwide occur in low- and middle-income countries?
What percentage of sepsis cases and sepsis-related deaths worldwide occur in low- and middle-income countries?
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Which of the following is a characteristic of septic shock?
Which of the following is a characteristic of septic shock?
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In critically ill patients, which of the following is the most common source of nosocomial infections?
In critically ill patients, which of the following is the most common source of nosocomial infections?
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What is the by-product of anaerobic metabolism in cells?
What is the by-product of anaerobic metabolism in cells?
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What is the consequence of impaired sodium-potassium pump function in cells?
What is the consequence of impaired sodium-potassium pump function in cells?
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What is the ultimate consequence of cellular damage due to septic shock?
What is the ultimate consequence of cellular damage due to septic shock?
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What is the primary cause of lactic acid buildup in the initiation stage of shock?
What is the primary cause of lactic acid buildup in the initiation stage of shock?
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At what stage of shock can the condition be reversed with minimal morbidity if appropriate interventions are initiated?
At what stage of shock can the condition be reversed with minimal morbidity if appropriate interventions are initiated?
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What is the primary consequence of the deterioration of the cardiovascular system in the progressive stage of shock?
What is the primary consequence of the deterioration of the cardiovascular system in the progressive stage of shock?
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What is the characteristic of the irreversible/refractory stage of shock?
What is the characteristic of the irreversible/refractory stage of shock?
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What is the primary goal of interventions in the progressive stage of shock?
What is the primary goal of interventions in the progressive stage of shock?
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What is the outcome of the irreversible/refractory stage of shock?
What is the outcome of the irreversible/refractory stage of shock?
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Study Notes
Definition and Objectives
- Shock is a medical emergency that affects all body systems, making it life-threatening.
- At the end of the presentation, students should be able to effectively manage shock and hemorrhage in emergency and trauma situations.
Definition of Shock
- Shock is a clinical syndrome characterized by inadequate tissue perfusion, resulting in cellular, metabolic, and hemodynamic derangements.
- Shock can be defined as a condition in which systemic blood pressure is inadequate to deliver oxygen and nutrients to support vital organs and cellular function, leading to cellular and tissue injury.
Review of Circulatory System
- Tissue perfusion requires a balance of:
- Adequate cardiac pump (myocardial contractility)
- Effective vasculature (adequate vascular tone)
- Sufficient blood volume
- Blood flow (dependent on Mean Arterial Pressure, MAP)
Classification of Shock
Hypovolemic Shock
- Occurs after a loss of intravascular fluid volume (whole blood, plasma, or water and electrolytes)
- Can be either absolute or relative volume loss
- Relative hypovolemia: fluid shift from vascular space to extravascular space (e.g., intracavitary space, third spacing)
Cardiogenic Shock
- Occurs when the heart's ability to contract and pump blood is impaired
- Causes: coronary (myocardial infarction) or non-coronary (cardiac tamponade, dysrhythmias)
- Leading cause of death from acute myocardial infarction
Obstructive Shock
- Occurs when there is a physical impairment to adequate circulatory blood flow
- Causes: impaired diastolic filling, increased right ventricular afterload, increased left ventricular afterload
- Obstruction of the heart or great vessels impedes venous return to the right side of the heart or prevents effective pumping action
Distributive Shock
- Caused by:
- Anaphylactic shock (acute, life-threatening hypersensitivity reaction)
- Neurogenic shock (loss of sympathetic tone, e.g., spinal cord injury, spinal anesthesia)
- Sepsis (systemic inflammatory response to a documented or suspected infection)
- Characterized by vasodilation, leading to inadequate tissue perfusion
Pathophysiology of Shock at Cellular Level
- Normal cellular metabolism: Fuel + Oxygen → Carbon dioxide + water + ATP
- Reduced oxygen supply leads to anaerobic metabolism, producing less ATP and lactic acid
- Lactic acid accumulation creates an acidotic intracellular environment, leading to cell damage and death
Stages of Shock
Initiation Stage
- Shift from aerobic to anaerobic metabolism, causing lactic acid buildup
- No obvious clinical indications of hypoperfusion
- Decrease in cardiac output can be detected on invasive hemodynamic monitors
Compensatory Stage
- Body activates compensatory mechanisms to maintain blood flow to vital organs and restore homeostasis
- Appropriate interventions can reverse shock with minimal morbidity
Progressive Stage
- Compensatory mechanisms can no longer maintain tissue perfusion
- Deterioration of the cardiovascular system perpetuates symptoms of shock
- Aggressive interventions are necessary to prevent MODS (Multiple Organ Dysfunction Syndrome)
Irreversible/Refractory Stage
- Point at which organ damage is so severe that the patient does not respond to treatment
- Multiple organ dysfunction progressing to complete organ failure, with impending death
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Description
Learn about shock, a life-threatening medical emergency that affects all body systems, its causes, and clinical manifestations. Understand the effects of shock and its progression to organ failure and death.