5 Questions
Which toxin produced by Shigella dysenteriae acts as an enterotoxin causing necrosis of the cells of the colon?
Shiga toxin
What is the main mode of transmission for Shigella spp.?
Oral-fecal route
What are the clinical signs of Shigella dysenteriae infection?
Abdominal cramps, tenesmus, bloody diarrhea with abundant pus, and fever
What is the recommended treatment for Shigella dysenteriae infection?
Ampicillin or third-generation cephalosporins
What is the most effective prophylaxis for Shigella dysenteriae infection?
Public health measures
Study Notes
Shigella dysenteriae Toxin
- The toxin produced by Shigella dysenteriae that acts as an enterotoxin, causing necrosis of the cells of the colon, is Shiga toxin.
Transmission of Shigella spp.
- The main mode of transmission for Shigella spp. is through the fecal-oral route, often via contaminated food and water.
Clinical Signs of Shigella dysenteriae Infection
- Clinical signs of Shigella dysenteriae infection include abdominal cramps, diarrhea, fever, and tenesmus (a feeling of incomplete bowel evacuation).
Recommended Treatment
- The recommended treatment for Shigella dysenteriae infection is antibiotic therapy, specifically with fluoroquinolones or cephalosporins, to shorten the duration of illness and reduce the risk of complications.
Prophylaxis for Shigella dysenteriae Infection
- The most effective prophylaxis for Shigella dysenteriae infection is proper hand hygiene, particularly washing hands with soap and water, to prevent the spread of the bacteria.
Test your knowledge of Shigella spp. and its role in causing bacillary dysentery with this quiz. Explore the epidemiology, transmission, and virulence factors of Shigella dysenteriae. Ideal for medical microbiology students seeking to reinforce their understanding of Gram-negative bacteria.
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