Podcast
Questions and Answers
Which hormone induces antrum formation and stimulates granulosa cell proliferation during the follicular phase of the ovarian cycle?
Which hormone induces antrum formation and stimulates granulosa cell proliferation during the follicular phase of the ovarian cycle?
- LH
- FSH (correct)
- Estrogen
- Androgen
What is the role of LH and FSH in estrogen synthesis and secretion by the follicle?
What is the role of LH and FSH in estrogen synthesis and secretion by the follicle?
- They promote androgen production in granulosa cells
- They stimulate thecal cells to produce androgens
- They convert thecal androgens into estrogens in granulosa cells (correct)
- They inhibit the production of androgens and estrogens
What is the function of thecal cells in the ovarian cycle?
What is the function of thecal cells in the ovarian cycle?
- To produce androgens (correct)
- To produce estrogens
- To stimulate granulosa cell proliferation
- To induce antrum formation
What is the role of estrogen in inhibiting the hypothalamus and anterior pituitary through negative feedback?
What is the role of estrogen in inhibiting the hypothalamus and anterior pituitary through negative feedback?
What does estrogen directly inhibit in the gonadotropes?
What does estrogen directly inhibit in the gonadotropes?
What is the primary factor that determines the rate of estrogen secretion during the follicular phase?
What is the primary factor that determines the rate of estrogen secretion during the follicular phase?
What is the function of rising moderate levels of estrogen during the follicular phase?
What is the function of rising moderate levels of estrogen during the follicular phase?
Which cells in the ovary contain aromatase to convert androgens into estrogens?
Which cells in the ovary contain aromatase to convert androgens into estrogens?
What is the function of FSH in the ovarian cycle?
What is the function of FSH in the ovarian cycle?
What is the relationship between LH and androgen production in thecal cells during the follicular phase?
What is the relationship between LH and androgen production in thecal cells during the follicular phase?
Study Notes
- The follicular phase of the ovarian cycle requires hormonal support for follicular development and estrogen secretion.
- FSH induces antrum formation and both FSH and estrogen stimulate granulosa cell proliferation.
- LH and FSH are required for estrogen synthesis and secretion by the follicle.
- Thecal cells produce androgens while granulosa cells contain aromatase to convert androgens into estrogens.
- LH stimulates androgen production in thecal cells while FSH promotes conversion of thecal androgens into estrogens in granulosa cells.
- The rate of estrogen secretion primarily depends on the circulating level of LH.
- Secreted estrogen inhibits the hypothalamus and anterior pituitary through negative feedback.
- Estrogen directly inhibits FSH secretion by the gonadotropes.
- Estrogen contributes to antral fluid and stimulates further granulosa cell proliferation.
- Rising moderate levels of estrogen inhibit GnRH secretion, suppressing GnRH-prompted release of FSH and LH from the anterior pituitary.
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