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10 Questions

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Control of Follicular Function S746

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Questions and Answers

Which hormone induces antrum formation and stimulates granulosa cell proliferation during the follicular phase of the ovarian cycle?

FSH (correct)

Estrogen

Androgen

What is the role of LH and FSH in estrogen synthesis and secretion by the follicle?

They promote androgen production in granulosa cells

They stimulate thecal cells to produce androgens

They convert thecal androgens into estrogens in granulosa cells (correct)

They inhibit the production of androgens and estrogens

What is the function of thecal cells in the ovarian cycle?

To produce androgens (correct)

To produce estrogens

To stimulate granulosa cell proliferation

To induce antrum formation

What is the role of estrogen in inhibiting the hypothalamus and anterior pituitary through negative feedback?

To suppress the production of FSH and LH Signup and view all the answers

What does estrogen directly inhibit in the gonadotropes?

FSH secretion Signup and view all the answers

What is the primary factor that determines the rate of estrogen secretion during the follicular phase?

The circulating level of LH Signup and view all the answers

What is the function of rising moderate levels of estrogen during the follicular phase?

To inhibit GnRH secretion and suppress the release of FSH and LH from the anterior pituitary Signup and view all the answers

Which cells in the ovary contain aromatase to convert androgens into estrogens?

Granulosa cells Signup and view all the answers

What is the function of FSH in the ovarian cycle?

To stimulate granulosa cell proliferation Signup and view all the answers

What is the relationship between LH and androgen production in thecal cells during the follicular phase?

LH promotes androgen production in thecal cells Signup and view all the answers

Study Notes

The follicular phase of the ovarian cycle requires hormonal support for follicular development and estrogen secretion.
FSH induces antrum formation and both FSH and estrogen stimulate granulosa cell proliferation.
LH and FSH are required for estrogen synthesis and secretion by the follicle.
Thecal cells produce androgens while granulosa cells contain aromatase to convert androgens into estrogens.
LH stimulates androgen production in thecal cells while FSH promotes conversion of thecal androgens into estrogens in granulosa cells.
The rate of estrogen secretion primarily depends on the circulating level of LH.
Secreted estrogen inhibits the hypothalamus and anterior pituitary through negative feedback.
Estrogen directly inhibits FSH secretion by the gonadotropes.
Estrogen contributes to antral fluid and stimulates further granulosa cell proliferation.
Rising moderate levels of estrogen inhibit GnRH secretion, suppressing GnRH-prompted release of FSH and LH from the anterior pituitary.

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