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Questions and Answers
What is the primary mechanism of action of Lysergic acid diethylamide (LSD) in peripheral tissues?
What is the primary mechanism of action of Lysergic acid diethylamide (LSD) in peripheral tissues?
- Antagonist action at serotonin receptors
- Inhibition of prolactin secretion
- Potent 5-HT2 blocker (correct)
- Agonist action at dopamine receptors
Which type of receptors are agonized by some ergot alkaloids in the pituitary?
Which type of receptors are agonized by some ergot alkaloids in the pituitary?
- Serotonin receptors
- Adrenergic receptors
- Dopamine receptors (correct)
- Cholinergic receptors
What is the primary use of ergotamine in the treatment of migraine?
What is the primary use of ergotamine in the treatment of migraine?
- Pain relief
- Prophylaxis
- Vasoconstriction
- Acute attack treatment (correct)
Why are triptan derivatives preferred over ergots in the treatment of migraine?
Why are triptan derivatives preferred over ergots in the treatment of migraine?
What is the primary effect of ergonovine and ergotamine in the treatment of obstetric bleeding?
What is the primary effect of ergonovine and ergotamine in the treatment of obstetric bleeding?
Why must ergonovine and ergotamine not be given before delivery of the placenta?
Why must ergonovine and ergotamine not be given before delivery of the placenta?
What is the effect of some ergot alkaloids on prolactin secretion?
What is the effect of some ergot alkaloids on prolactin secretion?
What is the primary mechanism of action of semisynthetic ergot derivatives, such as bromocriptine and pergolide?
What is the primary mechanism of action of semisynthetic ergot derivatives, such as bromocriptine and pergolide?
What is the effect of LSD on dopamine receptors in the CNS?
What is the effect of LSD on dopamine receptors in the CNS?
What is the primary difference between ergotamine and dihydroergotamine?
What is the primary difference between ergotamine and dihydroergotamine?
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