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Serotonin Physiology Quiz

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Questions and Answers

What is the primary mechanism of action of Lysergic acid diethylamide (LSD) in peripheral tissues?

Antagonist action at serotonin receptors

Inhibition of prolactin secretion

Potent 5-HT2 blocker (correct)

Agonist action at dopamine receptors

Which type of receptors are agonized by some ergot alkaloids in the pituitary?

Serotonin receptors

Adrenergic receptors

Dopamine receptors (correct)

Cholinergic receptors

What is the primary use of ergotamine in the treatment of migraine?

Pain relief

Prophylaxis

Vasoconstriction

Acute attack treatment (correct)

Why are triptan derivatives preferred over ergots in the treatment of migraine?

Triptans have lower toxicity Signup and view all the answers

What is the primary effect of ergonovine and ergotamine in the treatment of obstetric bleeding?

Powerful and long-lasting contraction Signup and view all the answers

Why must ergonovine and ergotamine not be given before delivery of the placenta?

They may interfere with placental delivery Signup and view all the answers

What is the effect of some ergot alkaloids on prolactin secretion?

Inhibition of prolactin secretion Signup and view all the answers

What is the primary mechanism of action of semisynthetic ergot derivatives, such as bromocriptine and pergolide?

Dopamine receptor agonism Signup and view all the answers

What is the effect of LSD on dopamine receptors in the CNS?

Agonism Signup and view all the answers

What is the primary difference between ergotamine and dihydroergotamine?

Ergotamine is used in acute attacks, while dihydroergotamine is used in prophylaxis Signup and view all the answers