Podcast
Questions and Answers
What is the mainstay treatment for severe stages of sarcoidosis?
What is the mainstay treatment for severe stages of sarcoidosis?
Which clinical feature is most commonly associated with systemic subtypes of JIA?
Which clinical feature is most commonly associated with systemic subtypes of JIA?
What is required for a diagnosis of JIA in pediatric patients?
What is required for a diagnosis of JIA in pediatric patients?
Which medication is considered the cornerstone of medical management for JIA?
Which medication is considered the cornerstone of medical management for JIA?
Signup and view all the answers
What potential growth abnormality can occur as a result of JIA?
What potential growth abnormality can occur as a result of JIA?
Signup and view all the answers
What is a common adverse effect of long-term high-dose corticosteroid use?
What is a common adverse effect of long-term high-dose corticosteroid use?
Signup and view all the answers
Which symptom is least likely to be a characteristic feature of JIA?
Which symptom is least likely to be a characteristic feature of JIA?
Signup and view all the answers
Which treatment option is recommended to manage pain and stiffness associated with oligoarthritis in JIA?
Which treatment option is recommended to manage pain and stiffness associated with oligoarthritis in JIA?
Signup and view all the answers
What is a characteristic hematologic abnormality commonly associated with lupus?
What is a characteristic hematologic abnormality commonly associated with lupus?
Signup and view all the answers
Which laboratory test result is particularly indicative of systemic inflammation during a lupus exacerbation?
Which laboratory test result is particularly indicative of systemic inflammation during a lupus exacerbation?
Signup and view all the answers
What role does the ANA test play in the diagnosis of systemic lupus erythematosus?
What role does the ANA test play in the diagnosis of systemic lupus erythematosus?
Signup and view all the answers
Which pharmacologic agent is considered the mainstay of treatment for lupus?
Which pharmacologic agent is considered the mainstay of treatment for lupus?
Signup and view all the answers
Which dietary recommendation is advised for lupus patients at risk of cardiovascular issues?
Which dietary recommendation is advised for lupus patients at risk of cardiovascular issues?
Signup and view all the answers
What is a significant risk associated with lupus patients undergoing dental procedures?
What is a significant risk associated with lupus patients undergoing dental procedures?
Signup and view all the answers
Which of the following is not a common manifestation of lupus?
Which of the following is not a common manifestation of lupus?
Signup and view all the answers
What condition involves inflammation and damage to blood vessel walls, leading to tissue necrosis?
What condition involves inflammation and damage to blood vessel walls, leading to tissue necrosis?
Signup and view all the answers
Which of the following is NOT a characteristic symptom of Giant Cell Arteritis (GCA)?
Which of the following is NOT a characteristic symptom of Giant Cell Arteritis (GCA)?
Signup and view all the answers
What is the primary goal of treatment for Giant Cell Arteritis?
What is the primary goal of treatment for Giant Cell Arteritis?
Signup and view all the answers
Which of the following criteria does NOT help in the diagnosis of Giant Cell Arteritis?
Which of the following criteria does NOT help in the diagnosis of Giant Cell Arteritis?
Signup and view all the answers
Which vascular phenomenon is characterized by pain, pallor, cyanosis, and redness in fingers due to vasospasm?
Which vascular phenomenon is characterized by pain, pallor, cyanosis, and redness in fingers due to vasospasm?
Signup and view all the answers
What is a common complication associated with Giant Cell Arteritis?
What is a common complication associated with Giant Cell Arteritis?
Signup and view all the answers
What is the average duration of high dose prednisone therapy for Giant Cell Arteritis?
What is the average duration of high dose prednisone therapy for Giant Cell Arteritis?
Signup and view all the answers
Raynaud Phenomenon can be classified into two types. Which of the following is a characteristic of secondary Raynaud?
Raynaud Phenomenon can be classified into two types. Which of the following is a characteristic of secondary Raynaud?
Signup and view all the answers
Which mechanism is generally believed to trigger the episodes of Raynaud Phenomenon?
Which mechanism is generally believed to trigger the episodes of Raynaud Phenomenon?
Signup and view all the answers
What is a common initial symptom of rheumatoid arthritis?
What is a common initial symptom of rheumatoid arthritis?
Signup and view all the answers
Which of the following deformities is commonly seen in later stages of rheumatoid arthritis?
Which of the following deformities is commonly seen in later stages of rheumatoid arthritis?
Signup and view all the answers
Which of the following is NOT a criterion for diagnosing rheumatoid arthritis?
Which of the following is NOT a criterion for diagnosing rheumatoid arthritis?
Signup and view all the answers
What specific sign might be palpated during a physical exam of a joint affected by rheumatoid arthritis?
What specific sign might be palpated during a physical exam of a joint affected by rheumatoid arthritis?
Signup and view all the answers
Which joint group is least likely to be affected by rheumatoid arthritis?
Which joint group is least likely to be affected by rheumatoid arthritis?
Signup and view all the answers
How long does morning stiffness last in individuals with rheumatoid arthritis?
How long does morning stiffness last in individuals with rheumatoid arthritis?
Signup and view all the answers
What type of swelling is most characteristic of rheumatoid arthritis?
What type of swelling is most characteristic of rheumatoid arthritis?
Signup and view all the answers
Which of the following is a hallmark feature of rheumatoid arthritis in the hands?
Which of the following is a hallmark feature of rheumatoid arthritis in the hands?
Signup and view all the answers
Which of the following symptoms is NOT typically associated with Polymyalgia Rheumatica?
Which of the following symptoms is NOT typically associated with Polymyalgia Rheumatica?
Signup and view all the answers
What is the typical demographic presentation for Polymyalgia Rheumatica?
What is the typical demographic presentation for Polymyalgia Rheumatica?
Signup and view all the answers
Which diagnostic finding is commonly associated with Giant Cell Arteritis?
Which diagnostic finding is commonly associated with Giant Cell Arteritis?
Signup and view all the answers
What is the first-line treatment for Polymyalgia Rheumatica?
What is the first-line treatment for Polymyalgia Rheumatica?
Signup and view all the answers
Which of the following conditions should be excluded before diagnosing Polymyalgia Rheumatica?
Which of the following conditions should be excluded before diagnosing Polymyalgia Rheumatica?
Signup and view all the answers
What is a classic symptom of Giant Cell Arteritis?
What is a classic symptom of Giant Cell Arteritis?
Signup and view all the answers
Which test result is expected to be normal in a patient diagnosed with Polymyalgia Rheumatica?
Which test result is expected to be normal in a patient diagnosed with Polymyalgia Rheumatica?
Signup and view all the answers
What is a known environmental factor believed to influence the prevalence of Polymyalgia Rheumatica?
What is a known environmental factor believed to influence the prevalence of Polymyalgia Rheumatica?
Signup and view all the answers
Which of the following features are included in the Cushingoid appearance?
Which of the following features are included in the Cushingoid appearance?
Signup and view all the answers
What is a common central nervous system side effect associated with certain medications?
What is a common central nervous system side effect associated with certain medications?
Signup and view all the answers
Which risk factors are classified as being in the moderate risk category for gastrointestinal toxicity?
Which risk factors are classified as being in the moderate risk category for gastrointestinal toxicity?
Signup and view all the answers
What are the potential consequences of raised blood pressure related to certain medications?
What are the potential consequences of raised blood pressure related to certain medications?
Signup and view all the answers
Identify the first-line biologic therapy for treating rheumatoid arthritis (RA).
Identify the first-line biologic therapy for treating rheumatoid arthritis (RA).
Signup and view all the answers
What are the reported side effects of methotrexate as a treatment?
What are the reported side effects of methotrexate as a treatment?
Signup and view all the answers
When should caution be taken with NSAID use in relation to gastrointestinal health?
When should caution be taken with NSAID use in relation to gastrointestinal health?
Signup and view all the answers
Which of the following is NOT a potential effect of glucose metabolism disruption?
Which of the following is NOT a potential effect of glucose metabolism disruption?
Signup and view all the answers
Study Notes
Seronegative Spondyloarthropathies (SPA)
- Spondylarthritis encompasses disorders with similar clinical features.
- Common disorders include: Psoriatic Arthritis, Enteropathic Spondyloarthropathies, Ankylosing Spondylitis, and Reactive Arthritis.
- Clinical features of SPA often include inflammatory back pain (more than 3 months), sacroiliitis (inflammation of the sacroiliac joints), peripheral joint inflammation, and sometimes eye or skin inflammation (associated with psoriasis). Bowel inflammation may also be present.
Ankylosing Spondylitis (AS)
- The most common seronegative spondyloarthropathy.
- Typically begins in the 20s or 30s.
- A chronic systemic inflammatory disease affecting the sacroiliac joints, intervertebral disc spaces, and peripheral joints.
Patients with Chronic Back Pain and Progressive Spinal Stiffness
- Patients with SPA often experience chronic back pain that progresses to spinal stiffness and disability.
- Genetics, most commonly HLA-B27, is a major predisposing gene.
- Inflammation in and around joints causes granulation tissue formation, leading to joint fusion.
Inflammatory Response
- Inflammation affects not only joints but also the eyes, lungs, heart, kidneys, and peripheral nervous system.
Clinical Presentation of Reactive Arthritis (Reiter Syndrome)
- Arthritis that follows after or during other infection elsewhere in the body (e.g., gut/genitourinary infections).
- Symptoms begin within one to four weeks of the infection.
- Characteristic symptoms include eye involvement (conjunctivitis), urethritis, and arthritis.
- Symptoms typically resolve within one year.
Psoriatic Arthritis
- Chronic inflammatory arthritis associated with psoriasis.
- Presents as worse symptoms in the morning.
- Presents with joint involvement (often asymmetric), with spondylitis possible.
- Other features like nail and skin changes (characteristic of psoriasis) typically present.
Polymyalgia Rheumatica and Giant Cell Arteritis (PMR/CGA)
- Characterized by diffuse aching and stiffness, typically in the shoulder and pelvic girdle.
- Affects older adults, mostly women.
- Onset is abrupt.
- Morning stiffness is a common symptom, but not necessarily a defining symptom, though its absence excludes PMR.
- Low-grade fever is often present.
Vasculitis
- A group of disorders involving inflammation and damage to blood vessels, causing tissue necrosis.
- Broad categories of vasculitis include large vessel (e.g., giant cell arteritis), medium vessel (e.g., polyarteritis nodosa, takayasu arteritis) and small vessel vasculitis.
- Some vasculitides are more common in certain age groups or associated with specific conditions.
Sjogren's Syndrome
- Characterized by dry eyes (keratoconjunctivitis sicca), and dry mouth (xerostomia).
- A chronic autoimmune disease.
- Caused by dysfunction of the exocrine glands (producing saliva, tears, etc.)
- Patients often present with dry eyes and mouth.
Fibromyalgia
- Chronic widespread pain.
- Often characterized by widespread pain, fatigue, numbness, and tingling.
- Diagnosis is based on symptoms and physical examination, including tender points.
Sarcoidosis
- A multisystem granulomatous disease of unknown cause.
- Characterized by inflammatory lesions and is typically diagnosed based on clinical presentation and imaging plus biopsy.
- Various organ systems may be involved.
- May cause scarring and reduced lung function.
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Related Documents
Description
This quiz covers the essential features and disorders associated with seronegative spondyloarthropathies, including Ankylosing Spondylitis and its clinical characteristics. You will explore the impact of these conditions on patients, particularly focusing on chronic back pain and spinal stiffness. Test your understanding of the common disorders and symptoms linked to this group of diseases.
