Podcast
Questions and Answers
What is the definition of a polyp?
What is the definition of a polyp?
- A growth projecting from mucus membrane (correct)
- A benign tumor in the large intestine
- A connective tissue core surrounded by smooth muscle fibers
- A neoplasm formed from monoclonal cells
What type of polyp has the potential for malignant transformation?
What type of polyp has the potential for malignant transformation?
- Inflammatory polyps
- Adenomatous polyps (correct)
- Hamartomatous polyps
- Hyperplastic polyps
What is the main characteristic of hyperplastic polyps?
What is the main characteristic of hyperplastic polyps?
- They have smooth muscle fibers in the connective tissue core
- They show dense inflammatory cells in the connective tissue core
- They are formed of connective tissue core surrounded by epithelium from 3 surfaces
- They show hyperplastic colonic glands (correct)
What is the gender distribution of large intestinal adenocarcinoma?
What is the gender distribution of large intestinal adenocarcinoma?
What age group is most commonly affected by large intestinal adenocarcinoma?
What age group is most commonly affected by large intestinal adenocarcinoma?
Which genetic syndrome is associated with a high risk for large intestinal adenocarcinoma?
Which genetic syndrome is associated with a high risk for large intestinal adenocarcinoma?
Which gene is implicated in familial polyposis coli syndrome?
Which gene is implicated in familial polyposis coli syndrome?
What is the minimum number of polyps necessary for the diagnosis of familial polyposis coli syndrome?
What is the minimum number of polyps necessary for the diagnosis of familial polyposis coli syndrome?
In the adenoma carcinoma model, what is the first mutation that initiates the defect?
In the adenoma carcinoma model, what is the first mutation that initiates the defect?
Which site is the commonest for large intestinal adenocarcinoma?
Which site is the commonest for large intestinal adenocarcinoma?
What is the depth of invasion for a T3 stage large intestinal adenocarcinoma?
What is the depth of invasion for a T3 stage large intestinal adenocarcinoma?
What is the primary mode of spread for large intestinal adenocarcinoma to the liver and lungs?
What is the primary mode of spread for large intestinal adenocarcinoma to the liver and lungs?
Which term describes the microscopic appearance of malignant glands surrounded by desmoplasia in large intestinal adenocarcinoma?
Which term describes the microscopic appearance of malignant glands surrounded by desmoplasia in large intestinal adenocarcinoma?
In which type of large intestinal adenocarcinoma does the defect start with a mutation in the mismatch repair gene?
In which type of large intestinal adenocarcinoma does the defect start with a mutation in the mismatch repair gene?
What is the characteristic feature of cells in large intestinal adenocarcinoma indicative of malignancy?
What is the characteristic feature of cells in large intestinal adenocarcinoma indicative of malignancy?
What grading factor depends on the percentage of glandular formations in large intestinal adenocarcinoma?
What grading factor depends on the percentage of glandular formations in large intestinal adenocarcinoma?
