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What is the primary use of carvedilol?
What is the primary use of carvedilol?
What class of medication does carvedilol belong to?
What class of medication does carvedilol belong to?
Which side effect is commonly associated with carvedilol?
Which side effect is commonly associated with carvedilol?
What is the common dosage form for carvedilol?
What is the common dosage form for carvedilol?
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How does carvedilol help reduce blood pressure?
How does carvedilol help reduce blood pressure?
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What is a common indication for the use of selective β1 antagonists like Bisoprolol?
What is a common indication for the use of selective β1 antagonists like Bisoprolol?
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Which of the following is a known side effect of Bisoprolol?
Which of the following is a known side effect of Bisoprolol?
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What is the mechanism of action of Bisoprolol?
What is the mechanism of action of Bisoprolol?
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What is the typical dosage form of Bisoprolol?
What is the typical dosage form of Bisoprolol?
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Which of the following drugs is also a selective β1 antagonist along with Bisoprolol?
Which of the following drugs is also a selective β1 antagonist along with Bisoprolol?
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Study Notes
Selective β1 Antagonists
- Bisoprolol is a selective β1 antagonist used primarily in hypertensive patients with impaired pulmonary function and for chronic stable angina.
- Brand names include Concor cor and Cardex, with the scientific name being Bisoprol.
- Common side effects involve headaches, extreme fatigue, slow heart rate, nausea, and dizziness.
- The drug is available in tablet form with a typical dose of 2.5 mg.
- Other selective β1 antagonists include Atenolol and Nebivolol.
Carvedilol
- Carvedilol treats hypertension and heart failure, functioning as a non-selective beta-blocker that also blocks alpha receptors, promoting peripheral vasodilation to lower blood pressure.
- Beneficial for stable chronic heart failure patients.
- It is classified as an antagonist of both α and β adrenoceptors, with the brand name Carvidol.
- Available in tablet form with a standard dosage of 12.5 mg.
- Side effects may include orthostatic hypotension and dizziness.
Propranolol
- Propranolol, marketed as Inderal, is a non-selective β-adrenergic blocker.
- Indicated for hypertension, angina pectoris, myocardial infarction, migraine, and hyperthyroidism.
- Side effects include bronchoconstriction, arrhythmias, sexual impairment, and various CNS effects like depression and dizziness.
- Available in tablet form, with a typical dose of 40 mg.
- It blocks both β1 and β2 receptors with equal affinity and has sustained-release formulations for once-daily dosing.
Additional Selective β1 Antagonists
- Other selective β1 antagonists are Atenolol, Nebivolol, and Metoprolol.
- Brand and formulation details:
- Betaloc ZOK: Metoprolol succinate, 50 mg, controlled-release tablets.
- Nebilong: Nebivolol Hydrochloride, 5 mg.
- Nebilet: Nebivolol, 5 mg.
- Atenolol Tablets BP: 50 mg.
- Bisoprolol and extended-release metoprolol are used for chronic heart failure management.
- Nebivolol besides its β1 blocking action also stimulates nitric oxide release, causing vasodilation.
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Description
This quiz covers selective β1 antagonists, specifically Bisoprolol, including its indications, side effects, and mechanism of action. Understand its role in treating hypertension and angina, along with important dosage information. Test your knowledge on this essential cardiovascular medication.
