Questions and Answers
What is the trade name for bisoprolol?
Which of the following classifications does bisoprolol belong to?
What are the indications for bisoprolol?
Management of hypertension.
What is the action of bisoprolol?
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In which conditions is bisoprolol contraindicated?
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Which of the following is a caution for using bisoprolol?
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What are some adverse effects of bisoprolol?
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Which drug interactions may occur with bisoprolol?
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What is the recommended dosage for bisoprolol?
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What should be monitored during bisoprolol therapy?
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What lab test considerations exist for bisoprolol?
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What patient teaching is essential for bisoprolol?
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Study Notes
Trade Name
- Bisoprolol is available under the trade names Monocor and Zebeta.
Classification
- Bisoprolol is classified as an antihypertensive and a beta blocker.
Indications
- Primarily indicated for the management of hypertension.
Action
- Works by decreasing blood pressure and heart rate.
Contraindications
- Not recommended for patients with:
- Uncompensated Congestive Heart Failure (CHF)
- Pulmonary edema
- Cardiogenic shock
- Bradycardia or heart block
Cautions
- Use with caution in patients with:
- Renal and hepatic impairments
- Pulmonary diseases
- Diabetes mellitus (may mask hypoglycemia symptoms)
- Thyrotoxicosis
- History of severe allergic reactions
- Geriatric patients (increased sensitivity; initial dosage reduction recommended)
Adverse Effects
- Possible side effects include:
- Mental status changes, nervousness, nightmares
- Visual disturbances, nasal congestion
- Bronchospasm, wheezing
- Bradycardia, CHF, pulmonary edema
- Hypotension, peripheral vasoconstriction
- Gastrointestinal issues (constipation, diarrhea, N/V)
- Sexual dysfunction (erectile dysfunction, decreased libido)
- Diabetes-related issues (hyperglycemia, hypoglycemia)
- Joint and back pain
- Drug-induced lupus syndrome
Drug-Drug Interactions
- Potential interactions that may lead to:
- Additive myocardial depression with general anesthetics, IV phenytoin, verapamil
- Additive bradycardia with digoxin
- Additive hypotension with other antihypertensives, alcohol, nitrates
- Unopposed alpha-adrenergic stimulation with sympathomimetics (e.g., amphetamines, epinephrine)
- Altered effectiveness of insulin and oral hypoglycemic agents (dose adjustments may be needed)
- Reduced effectiveness of theophylline
- Decreased benefits of dopamine or dobutamine
- Caution advised within 14 days of MAO inhibitor therapy
Dosage
- Commonly prescribed dosage is:
- Oral: 5 mg once daily; may increase to 10 mg, with a range of 2.5-20 mg/day.
Assessment
- Regular monitoring needed for:
- Blood pressure, ECG, and pulse during dosage adjustments and periodically thereafter
- Intake and output ratios and daily weights
- Signs and symptoms of CHF
- Frequency of prescription refills to assess adherence
Lab Test Considerations
- Bisoprolol may affect lab results by:
- Increasing BUN, serum lipoprotein, potassium, triglyceride, and uric acid levels
- Elevating ANA titers
- Increasing blood glucose levels
Patient Education
- Importance of informing patients about bisoprolol's purpose.
- Advising patients to report any signs of bleeding immediately to a healthcare professional.
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Description
Test your knowledge on Bisoprolol with these flashcards. Explore its trade names, classifications, indications, actions, and contraindications in a quick and efficient format. Perfect for students and healthcare professionals alike.
