12 Questions
Which of the following factors is NOT mentioned as influencing drug choice when susceptibility data is absent?
Patient's diet
What is the most likely causative organism for gram-positive cocci in the spinal fluid of a newborn infant?
Streptococcus agalactiae
What is the key difference between bacteriostatic and bactericidal drugs as described in the text?
Bacteriostatic drugs stop the growth of bacteria, while bactericidal drugs kill bacteria.
What is the key difference between minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) as described in the text?
MIC is the lowest concentration that prevents visible growth, while MBC is the lowest concentration that results in a 99.9% decline in colony count.
Which of the following statements about gram-positive cocci in the spinal fluid of a 40-year-old patient is correct?
They are most likely to be Streptococcus pneumoniae, which is frequently resistant to penicillin G.
Why are bactericidal drugs often the drugs of choice in seriously ill and immunocompromised patients according to the text?
Bactericidal drugs have a more aggressive antimicrobial action, which is beneficial for seriously ill and immunocompromised patients.
What is the primary reason antimicrobial drugs are effective in treating infections?
Their selective toxicity, which allows them to target the microorganism while being tolerated by the host
Which of the following is NOT a factor considered when selecting an appropriate antimicrobial agent?
The color of the patient's skin
What is the purpose of empiric therapy in the treatment of infections?
To provide immediate treatment before the infecting organism is identified
Which techniques are commonly used to identify the infecting organism?
Direct microscopic visualization and cultivation/identification
What is the primary advantage of identifying the infecting organism before initiating antimicrobial therapy?
It allows for the selection of the most effective antimicrobial agent
Which statement best describes the concept of selective toxicity in antimicrobial drugs?
The drug is more toxic to the microorganism than to the host, within a certain concentration range
Learn about the effectiveness of antimicrobial drugs in treating infections due to their selective toxicity. Explore how the concentration of the drug needs to be carefully controlled to target the microorganism while being tolerated by the host. Understand the factors involved in selecting the most appropriate antimicrobial agent.
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