Podcast
Questions and Answers
Which molecules mediate the initial step of low-affinity adhesion of circulating leukocytes to endothelial cells?
Which molecules mediate the initial step of low-affinity adhesion of circulating leukocytes to endothelial cells?
- Cadherins
- Selectins (correct)
- Immunoglobulins
- Integrins
What type of molecules are the extracellular domains of selectins similar to?
What type of molecules are the extracellular domains of selectins similar to?
- C-type lectins (correct)
- Enzymes
- Cytokines
- Glycoproteins
Which selectin is stored in cytoplasmic granules of endothelial cells and rapidly redistributed to the surface in response to various triggers?
Which selectin is stored in cytoplasmic granules of endothelial cells and rapidly redistributed to the surface in response to various triggers?
- E-selectin
- L-selectin
- V-selectin
- P-selectin (correct)
Which cytokines induce the synthesis and expression of E-selectin on the endothelial cell surface?
Which cytokines induce the synthesis and expression of E-selectin on the endothelial cell surface?
What type of molecules are selectins and their ligands?
What type of molecules are selectins and their ligands?
Which molecule binds carbohydrate structures in a calcium-dependent manner?
Which molecule binds carbohydrate structures in a calcium-dependent manner?
What is the function of selectins?
What is the function of selectins?
Which molecule is stored in cytoplasmic granules of endothelial cells and rapidly redistributed to the surface in response to various triggers?
Which molecule is stored in cytoplasmic granules of endothelial cells and rapidly redistributed to the surface in response to various triggers?
What induces the synthesis and expression of E-selectin on the endothelial cell surface?
What induces the synthesis and expression of E-selectin on the endothelial cell surface?
What are selectins similar to in terms of their extracellular domains?
What are selectins similar to in terms of their extracellular domains?
Which type of adhesion do selectins mediate between circulating leukocytes and endothelial cells?
Which type of adhesion do selectins mediate between circulating leukocytes and endothelial cells?
What is the primary function of P-selectin?
What is the primary function of P-selectin?
What triggers the rapid redistribution of P-selectin from cytoplasmic granules to the surface of endothelial cells?
What triggers the rapid redistribution of P-selectin from cytoplasmic granules to the surface of endothelial cells?
Which molecule induces the synthesis and expression of E-selectin on the endothelial cell surface?
Which molecule induces the synthesis and expression of E-selectin on the endothelial cell surface?
Which type of adhesion do selectins mediate between circulating leukocytes and endothelial cells?
Which type of adhesion do selectins mediate between circulating leukocytes and endothelial cells?
What is the primary function of P-selectin?
What is the primary function of P-selectin?
What type of molecules are the extracellular domains of selectins similar to?
What type of molecules are the extracellular domains of selectins similar to?
What triggers the synthesis and expression of E-selectin on the endothelial cell surface within 1 to 2 hours?
What triggers the synthesis and expression of E-selectin on the endothelial cell surface within 1 to 2 hours?
