Schizophrenia Overview and Treatment
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Questions and Answers

Which of the following is NOT considered a positive symptom of schizophrenia?

  • Avolition (correct)
  • Speech poverty
  • Hallucinations
  • Delusions
  • Which of the following is NOT a characteristic of negative symptoms of schizophrenia?

  • Difficulty maintaining goal-directed behavior
  • Avolition
  • Delusions of grandeur (correct)
  • Speech poverty
  • Schizophrenia is typically diagnosed in individuals between the ages of 15 and 35.

    True (A)

    What are the two main types of symptoms associated with schizophrenia?

    <p>Positive and negative symptoms</p> Signup and view all the answers

    Inter-rater reliability refers to the consistency of a clinician's diagnosis over time.

    <p>False (B)</p> Signup and view all the answers

    __________ are false beliefs that seem real to the individual suffering from schizophrenia, but are not true in reality.

    <p>Delusions</p> Signup and view all the answers

    _____ bias is an issue affecting the reliability of diagnosis, potentially leading to over-diagnosis of schizophrenia in certain ethnic groups.

    <p>Cultural</p> Signup and view all the answers

    Match the following symptoms of schizophrenia with their corresponding category:

    <p>Hallucinations = Positive Avolition = Negative Delusions = Positive Speech poverty = Negative</p> Signup and view all the answers

    Describe the concept of speech poverty as a negative symptom of schizophrenia.

    <p>Speech poverty refers to a significant reduction in the quantity or quality of speech, which may include reduced fluency, simplified language, and delayed verbal responses.</p> Signup and view all the answers

    Match the following concepts with their definitions:

    <p>Avolition = Difficulty initiating and maintaining goal-directed behavior Speech poverty = Significant reduction in quantity or quality of speech Delusions of grandeur = Exaggerated beliefs about one's importance or abilities Test-retest reliability = Consistency of diagnosis made by the same clinician on separate occasions Inter-rater reliability = Consistency of diagnosis between different clinicians for the same patient</p> Signup and view all the answers

    What is the difference between hallucinations and delusions?

    <p>Hallucinations are false perceptions of sensory stimuli, while delusions are false beliefs.</p> Signup and view all the answers

    Which of the following is NOT a factor that can contribute to cultural bias in schizophrenia diagnosis?

    <p>Use of standardized assessment tools across different cultures (A)</p> Signup and view all the answers

    Which of these is NOT a type of hallucination experienced by individuals with schizophrenia?

    <p>Somatic (B)</p> Signup and view all the answers

    Reliability in schizophrenia diagnosis refers to the accuracy of the diagnosis.

    <p>False (B)</p> Signup and view all the answers

    The dopamine hypothesis suggests that an excess of dopamine in certain brain regions is linked to schizophrenia.

    <p>True (A)</p> Signup and view all the answers

    Explain how cultural bias can affect the inter-rater reliability of schizophrenia diagnosis.

    <p>Cultural bias can affect inter-rater reliability because clinicians from different cultural backgrounds may interpret the same symptoms differently, potentially leading to inconsistent diagnoses.</p> Signup and view all the answers

    People of _____ descent are often over-diagnosed with schizophrenia, potentially due to cultural bias in diagnosis.

    <p>Afro-Caribbean</p> Signup and view all the answers

    Which of the following is a candidate gene associated with schizophrenia?

    <p>All of the above (D)</p> Signup and view all the answers

    The dopamine hypothesis suggests that schizophrenia is caused by an excess of dopamine activity in the brain.

    <p>True (A)</p> Signup and view all the answers

    What is the main difference between monozygotic (MZ) and dizygotic (DZ) twins in terms of genetic similarity?

    <p>MZ twins share 100% of their genes, while DZ twins share approximately 50%.</p> Signup and view all the answers

    The COMT gene controls an enzyme that breaks down ______.

    <p>dopamine</p> Signup and view all the answers

    Match the following terms with their correct definitions:

    <p>Concordance rate = The percentage of twin pairs in a study where both twins have the disorder Candidate gene = A gene that is thought to increase the risk of developing schizophrenia Polygenetic explanation = An explanation that suggests multiple genes contribute to the development of a disorder Meta-analysis = A statistical technique combining data from multiple studies to assess the overall effect</p> Signup and view all the answers

    Gottesman's (1991) review of over 40 twin studies indicated a higher concordance rate for DZ twins than for MZ twins, suggesting a strong genetic influence on schizophrenia.

    <p>False (B)</p> Signup and view all the answers

    Explain how a low activity variant of the COMT gene could contribute to symptoms of schizophrenia.

    <p>A low activity variant of the COMT gene would lead to reduced breakdown of dopamine, resulting in increased dopamine levels. Excess dopamine activity has been linked to hallucinations, a symptom often experienced by individuals with schizophrenia.</p> Signup and view all the answers

    Which of the following is NOT a potential limitation of twin studies in researching the genetic basis of schizophrenia?

    <p>Small sample sizes are frequently used (D)</p> Signup and view all the answers

    Flashcards

    Genetic Basis of Schizophrenia

    The theory that schizophrenia is inherited through faulty genes from parents.

    COMT Gene

    A candidate gene on chromosome 22 that affects dopamine breakdown in schizophrenia.

    Polygenic Explanation

    Schizophrenia arises from a complex interaction of multiple genes, not a single one.

    Twin Studies

    Research comparing concordance rates of schizophrenia in identical vs. non-identical twins.

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    Concordance Rate

    The percentage of twins sharing the same disorder, indicating genetic influence.

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    Gottesman (1991) Study

    A review showing 48% concordance for MZ and 17% for DZ twins in schizophrenia.

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    Joseph (2004) Meta-analysis

    Analysis questioning the genetic role in schizophrenia based on twin study data.

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    Excessive Dopamine

    Higher levels of dopamine linked to hallucinations in schizophrenia patients.

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    Delusions of Grandeur

    Beliefs about one's exaggerated abilities or importance, like being famous.

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    Negative Symptoms of Schizophrenia

    Reduction in normal functioning, including avolition and speech poverty.

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    Speech Poverty

    Significant reduction in the amount or quality of spoken words.

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    Avolition

    Difficulty in starting and maintaining goal-directed behavior.

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    Test-Retest Reliability

    Consistency of a diagnosis when assessed at different times.

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    Inter-Rater Reliability

    Agreement between different clinicians diagnosing the same patient.

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    Culture Bias

    Differential treatment or diagnosis of ethnic groups based on cultural norms.

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    Impact of Culture Bias

    Culture bias affects the reliability of diagnosis and classification of schizophrenia.

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    Schizophrenia

    A mental disorder affecting thought and perception, affecting 1% of the population.

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    Positive symptoms

    Symptoms that add to normal functioning, such as hallucinations and delusions.

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    Hallucinations

    Unusual perceptions unique to the individual, not sensed by others.

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    Delusions

    Irrational beliefs that feel real but are false.

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    Paranoid delusions

    Type of delusion involving the belief of being persecuted or followed.

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    Symptoms variability

    Symptoms can differ greatly in type and severity among individuals.

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    Study Notes

    Schizophrenia Specification

    • Classification of schizophrenia includes positive and negative symptoms
    • Positive symptoms: hallucinations (unusual perceptions), delusions (false beliefs)
    • Negative symptoms: avolition (lack of motivation), speech poverty
    • Reliability and validity in schizophrenia diagnosis: considers comorbidity, culture bias, gender bias, and symptom overlap
    • Biological explanations of schizophrenia encompass a range of factors, particularly genetic predispositions, which suggest that hereditary factors play a crucial role in an individual's likelihood of developing the disorder. Studies have indicated that individuals with a family history of schizophrenia are at higher risk. Additionally, neural correlates, such as the dopamine hypothesis, propose that abnormal dopamine activity in certain brain pathways may be closely linked to the manifestation of various symptoms, including hallucinations and delusions. Other neurotransmitters, like glutamate and serotonin, are also considered influential in understanding the biological underpinnings of this complex mental illness.
    • Psychological explanations: dysfunctional family, cognitive explanations (dysfunctional thought processing)
    • Drug therapy: typical and atypical antipsychotics
    • Cognitive behaviour therapy (CBT) and family therapy are used in the treatment of schizophrenia
    • Importance of an interactionist approach (diathesis-stress model) in explaining and treating schizophrenia.

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    Description

    This quiz covers the classification of schizophrenia, including positive and negative symptoms, diagnostic reliability, and treatment options. It explores biological and psychological explanations, as well as therapeutic approaches like drug therapy and cognitive-behavioral therapy. Test your knowledge on the complexities of schizophrenia.

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