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Schizophrenia Cellular-level Abnormalities Quiz

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Schizophrenia Cellular-level Abnormalities Quiz

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Questions and Answers

What cellular-level issue is related to schizophrenia?

Enhanced synaptic arborization

Cortical thinning (correct)

Neurogenesis in the hippocampus

Increased neural connectivity

What distinguishes the development of schizophrenia from Alzheimer's disease?

Both diseases exhibit symptoms in early childhood

Alzheimer's affects the temporal lobe while schizophrenia does not

Schizophrenia does not involve cortical loss and neural death (correct)

Both diseases involve similar patterns of cortical thinning

What developmental process may explain the onset of schizophrenia during late adolescence?

Synaptic overgrowth leading to increased neural connectivity

Brain undergoes profound changes including synaptic pruning (correct)

Decrease in synaptic pruning during late adolescence

Stagnation of neural development in late adolescence

What model proposes a cause for over-pruning in the development of schizophrenic brains?

Model B - Over-pruning occurs due to a steeper slope of pruning due to unknown developmental factors Signup and view all the answers

What is strongly associated with gray matter loss in schizophrenia?

Pro-inflammatory cytokines in the CSF Signup and view all the answers

What structural difference is observed in the brains of prodromal adolescents who later develop schizophrenia?

Rapid loss of gray matter in the PFC Signup and view all the answers

What is a possible cause of the disconnected nature of the schizophrenic brain?

Over-pruning Signup and view all the answers

What is a key difference between Alzheimer's and schizophrenia in terms of neural changes?

Schizophrenia has no neural death, only loss of neuropil Signup and view all the answers

What environmental factor is mentioned as a risk factor for schizophrenia?

Mom getting the flu while pregnant Signup and view all the answers

What is implicated in both positive and negative symptoms of schizophrenia?

Disruptions in dopamine and glutamate systems Signup and view all the answers