Salicylate Toxicity and Reye's Syndrome Quiz
18 Questions
3 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which of the following is NOT an effect of opioids on the body?

  • Urinary retention
  • Increased gastrointestinal motility (correct)
  • Cardiovascular vasodilation
  • Increased biliary sphincter tone and pressure
  • What is the main mechanism behind opioid tolerance?

  • Up-regulation of opioid receptors
  • Down-regulation of opioid receptors (correct)
  • Enhancement of opioid metabolism
  • Inhibition of neurotransmitter release
  • Which of the following is a symptom of opioid toxicity known as toxidrome?

  • Constipation
  • Euphoria
  • Pinpoint pupils (correct)
  • Miosis
  • What is a characteristic feature of physical dependence on opioids?

    <p>Withdrawal symptoms upon abrupt discontinuation</p> Signup and view all the answers

    Among the CNS effects of opioids, which one is responsible for the feeling of 'euphoria'?

    <p>Sedation</p> Signup and view all the answers

    Which of the following statements regarding opioid tolerance is true?

    <p>Moderate agonists do not exhibit cross-tolerance with full agonists</p> Signup and view all the answers

    Which condition is associated with the early sign of salicylate toxicity known as salicylism tinnitus?

    <p>Hypoprothrombinemia</p> Signup and view all the answers

    What is the first-line treatment for salicylate toxicity?

    <p>IV sodium bicarbonate administration</p> Signup and view all the answers

    Which NSAID is known for being the first NSAID for parenteral use?

    <p>Ketorolac (Toradol)</p> Signup and view all the answers

    What is a common adverse effect associated with the use of salicylates over a long duration?

    <p>Hepatic failure</p> Signup and view all the answers

    Reye's syndrome is commonly associated with the use of aspirin in children recovering from which viral infection?

    <p>Influenza (flu)</p> Signup and view all the answers

    Which medication should be used for short-term management of moderate pain states due to its hematologic toxicity limitation?

    <p>Ketorolac (Toradol)</p> Signup and view all the answers

    What is the major pathway of metabolism for Acetaminophen (APAP)?

    <p>Sulfation and Glucuronidation</p> Signup and view all the answers

    Which selective Cox-2 inhibitor was withdrawn from the market due to cardiovascular risks?

    <p>Rofecoxib</p> Signup and view all the answers

    What is the main advantage of Selective Cox-2 inhibitors over Non-Selective Cox inhibitors?

    <p>Lesser risk for NSAID-induced PUD</p> Signup and view all the answers

    Which NSAID category includes Etodolac and what is its brand name?

    <p>Oxicam Derivatives - Lodine</p> Signup and view all the answers

    Which NSAID category does Piroxicam belong to and what is its brand name?

    <p>Oxicam Derivatives - Feldene</p> Signup and view all the answers

    What is the major toxic metabolite of Acetaminophen (APAP)?

    <p>N-Acetyl Para Benzoquinone Imine</p> Signup and view all the answers

    More Like This

    Medication Dosage Guidelines Quiz
    48 questions
    Aspirin Absorption and Excretion
    15 questions
    Use Quizgecko on...
    Browser
    Browser