Saccharomyces Boulardii Overview

Questions and Answers

What is the brand name for saccharomyces boulardii?

Capsule

Probiotic

Florastor (correct)

Antifungal

What drug class does saccharomyces boulardii belong to?

Probiotic

What are the indications for saccharomyces boulardii?

GI colonization for treatment of diarrheal illnesses (antibiotic-associated diarrhea, celiac disease)

What dosage forms are available for saccharomyces boulardii?

Oral powder Signup and view all the answers

What is the dosing recommendation for saccharomyces boulardii?

250 mg po qd; may increase to 1 g po qd (in 2 div dose, 2 h after antibiotic dose for related diarrhea) Signup and view all the answers

Is renal dosing adjustment necessary for saccharomyces boulardii?

False Signup and view all the answers

What are the contraindications for saccharomyces boulardii?

Hypersensitivity, yeast allergy Signup and view all the answers

What drug interactions does saccharomyces boulardii have?

Antifungals Signup and view all the answers

What are common ADRs (adverse drug reactions) for saccharomyces boulardii?

Constipation, abdominal discomfort, bloating, nausea, thirst Signup and view all the answers

What are serious ADRs for saccharomyces boulardii?

None Signup and view all the answers

What are the monitoring parameters for saccharomyces boulardii?

Improvement in symptoms of abdominal discomfort and/or diarrhea Signup and view all the answers

What counseling points are important for saccharomyces boulardii?

Gas and bloating are common adverse effects at the start of treatment but generally diminish over several days of treatment. For antibiotic-associated diarrhea, start within 3 days of using antibiotics and continue for 3 days afterward. Product should be taken bid 2 hours after an antibiotic dose to prevent loss of potency. Product should be stored in its original packaging at room temperature to prevent loss of potency; do not use if broken or unsealed. Capsules may be opened and sprinkled into drinks or onto food (e.g., applesauce, yogurt, pudding). May be taken with or without food, but do not mix with carbonated, alcoholic, or hot beverages. Signup and view all the answers

Study Notes

Saccharomyces Boulardii Overview

Brand name: Florastor
Drug class: Probiotic

Indications and Dosage

Indicated for GI colonization to treat diarrheal illnesses, including:
- Antibiotic-associated diarrhea
- Celiac disease
Common dosage forms: Capsules, oral powder
Standard dosing:
- 250 mg orally, once daily
- Can be increased to 1 g orally, once daily (divided dose, taken 2 hours after antibiotic for related diarrhea)

Renal and Contraindications

Renal dosing adjustments: Not required
Contraindications include:
- Hypersensitivity
- Yeast allergy

Drug Interactions

Notable interactions with antifungal medications

Adverse Drug Reactions (ADRs)

Common ADRs:
- Constipation
- Abdominal discomfort
- Bloating
- Nausea
- Thirst
Serious ADRs: None reported

Monitoring and Counseling

Monitor for improvement in symptoms of abdominal discomfort and diarrhea.
Probiotics are typically well tolerated after initial days of therapy.
Counseling points:
- Gas and bloating may occur initially but typically subside within days.
- For antibiotic-associated diarrhea, start within 3 days of antibiotics and continue for 3 days after.
- Take product twice daily, 2 hours post-antibiotic dose to maintain potency.
- Store in original packaging at room temperature; do not use if broken or unsealed.
- Capsules can be opened and sprinkled on food or drinks (e.g., applesauce, yogurt).
- Can be taken with or without food, but avoid mixing with carbonated, alcoholic, or hot beverages.

Description

This quiz provides a comprehensive overview of Saccharomyces Boulardii, a probiotic used for treating diarrheal illnesses. It covers indications, dosing guidelines, contraindications, drug interactions, and common adverse reactions. Ideal for medical students and healthcare professionals looking to enhance their understanding of probiotic therapies.