Routes of Drug Administration Quiz

What is the most frequent route for drug administration?

Which of the following is NOT a dosage form taken by the oral route?

What is a major disadvantage of the oral route of drug administration?

What are the three main parenteral routes of drug administration?

Which route is used mainly when a patient is vomiting or unconscious?

What is a major advantage of the intravenous (IV) route for drug administration?

What type of injection administers the drug deep into the skeletal muscle for immediate effect?

Which of the following is a disadvantage of using the intravenous route?

What is the primary difference between topical and transdermal routes?

What is a significant characteristic of the respiratory route for drug delivery?

Routes of Drug Administration

Most common route is oral, but can be used for local effects in the GI tract
Rectal route is used for local action when oral administration is not possible due to vomiting or unconsciousness
Parenteral route refers to any administration method that is not oral, including subcutaneous, intramuscular, and intravenous
Topical administration is used for local action on the skin and examples include ointments, creams, pastes, and gels.
Transdermal route is used for systemic action and is applied topically to the skin.
Respiratory route is used to deliver drugs through the lungs in a gaseous or aerosol mist, with smaller particles reaching deeper into the lungs
Ophthalmic route is a subtype of topical used for local action in the eye, requiring sterile and isotonic dosage forms
Sublingual administration places the drug under the tongue, taking advantage of the rich blood supply for fast absorption

Prodrugs

Prodrugs are compounds that require enzymatic biochemical processes to produce the active drug
They can be used to modify drug absorption, increase solubility, and improve stability
Olsalazine is an example of a prodrug that is cleaved by azo reductase enzyme in the GIT to form the active drug 5-aminosalicylic acid.

Factors Affecting Drug Dosage

Drug dose is the lowest amount needed to achieve therapeutic effects without safety concerns
Factors that influence dose include age, body weight, and body surface area
Neonates require dose adjustments due to immature liver and renal function
Heavier individuals typically require a higher dose than leaner individuals
Taller individuals require a higher dose than shorter individuals

Test your knowledge on the various routes of drug administration, including oral, rectal, and parenteral methods. Understand how each route affects drug delivery and its applications in different medical scenarios. Challenge yourself with questions on topical, transdermal, and respiratory routes as well.