20 Questions
Which mechanism of drug absorption does not involve a carrier and is not saturable?
Passive diffusion
What is the driving force for passive diffusion of a drug?
Concentration gradient
Which type of drugs can readily move across most biologic membranes due to solubility in the membrane lipid bilayers?
Lipid-soluble drugs
Which process allows the passage of drugs into the interior of cells without requiring energy?
Facilitated diffusion
What is the half-life of oral morphine?
2 to 4 hours
What are the advantages of the sublingual and buccal routes of drug administration?
Ease of administration, rapid absorption, bypass of harsh GI environment, avoidance of first-pass metabolism
When are extended-release tablets needed for oral morphine administration?
When only two doses are needed
Why is the parenteral route of drug administration used for certain drugs?
Poor absorption from the GI tract, instability in the GI tract, unconscious patients
Which route of drug administration is effective for patients with respiratory disorders like asthma?
Oral Inhalation and Nasal Preparations
When local, rapid effects are needed in the central nervous system, which route of drug administration is necessary?
Intrathecal
Which route of administration is used when a local effect of the drug is desired?
Topical
How does the transdermal route of administration achieve systemic effects?
By applying drugs to the skin via a transdermal patch
Which route of administration allows for the most control over the amount of drug delivered to the body?
Intravenous (IV)
Which parenteral route of administration is ideal for drugs that are not absorbed orally?
Intravenous (IV)
Which type of preparations are absorbed slowly when administered intramuscularly?
Depot preparations
What are the major parenteral routes of drug administration?
Intravenous (IV), intramuscular, subcutaneous, and intradermal
What is the advantage of intravenous (IV) injection over other routes of administration?
Rapid effect and maximum control over drug delivery
Which type of drugs are suitable for intravenous (IV) delivery?
Neuromuscular blockers like rocuronium
What characterizes drugs administered intramuscularly (IM)?
Rapid absorption in nonaqueous vehicles
Which route of parenteral administration provides the most control over the actual dose of drug delivered to the body?
Intravenous (IV)
This quiz covers the administration of drugs through inhalation, specifically focusing on gases and aerosols. It discusses the effectiveness and convenience of this route for patients with respiratory disorders such as asthma and chronic obstructive pulmonary disease.
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